Reliability of FNAC as a diagnostic tool in lymphadenopathy

Abstract

INTRODUCTIONFine needle aspiration cytology in the evaluation lymph node lesions is a simple important diagnostic tool. 1 FNAC is a first line investigation modality for the evaluation of cervical lymphadenopathies. 2Lymphadenopathy is one of the commonest clinical presentations of patients attending outpatients' departments of most hospitals. The etiology of lymphadenopathy varies from reactive hyperplasia, granulomatous lesions, lymphoma and metastatic diseases.FNAC has been advocated as a useful method in comparison to more expensive surgical excision biopsy in developing countries with limited resources. 3 The use of fine needle aspiration cytology in the investigation of lymphadenopathy has become an acceptable and widely practiced safe simple rapid and minimally invasive technique. 4 The present study was undertaken to assess ABSTRACT Background: Fine needle aspiration cytology is a first line investigation modality for the evaluation of cervical lymphadenopathies. Cervical lymphadenopathy is one of the most common clinical presentations affecting all age groups. Fine needle aspiration cytology is a first line investigation modality for the evaluation of cervical lymphadenopathies. Cervical lymphadenopathy is one of the most common clinical presentations affecting all age groups. Methods: This study was carried out in the Department of Pathology of Government Medical CollegeThiruvananthapuram over a two year. Out of 1020 aspirations 122 cases where identified and included in the study. All the diagnosis obtained by fine needle aspiration cytology was correlated with histopathology. Results:The age of the patients ranged from seven years to seventy-eight years in which 44% were males and 56% were females. Incidence of non-neoplastic lymph node lesions was common during 2 to 4 decades. Incidence of neoplastic lymph node lesions was common during 4 to 6th decade. Reactive change and Tuberculosis were seen more common in females whereas Non-Hodgkin's lymphoma and metastatic tumors were more common in males. The overall accuracy of lymph node lesions in our study was found to be 90.98%, sensitivity 84 % and specificity 95.8%. Conclusions: Our study concluded that FNAC is simple, quick, minimally invasive technique to diagnose lymphadenopathy. The overall accuracy of lymph node lesions in our study was found to be 90.98%, sensitivity 84% and specificity 95.8%. Findings in this study are comparable and consistent with studies conducted elsewhere. The limitations of FNAC are that only positive results have clinical significance. The limitations have to be taken into account while interpreting the smears and skill has to be gained by constant practice.

Observational study on FNAC evaluation of peripheral lymph node swellings

“…The knowledge of the spectrum of lymphadenopathy in a particular area is important for making a definitive diagnosis [1]. Various researchers have described the pattern of diseases diagnosed on the basis of FNAC of peripheral lymph nodes in different parts of the country [6][7][8][9][10][11][12][13].Very few studies regarding this have been done in this area. Hence, this study was conducted.…”