Reliability and Validity of the Medical Outcomes Study Short Form-12 Version 2 (SF-12v2) in Adults with Non-Cancer Pain

Abstract

Limited evidence exists on how non-cancer pain (NCP) affects an individual’s health-related quality of life (HRQoL). This study aimed to validate the Medical Outcomes Study Short Form-12 Version 2 (SF-12v2), a generic measure of HRQoL, in a NCP cohort using the Medical Expenditure Panel Survey Longitudinal Files. The SF Mental Component Summary (MCS12) and SF Physical Component Summary (PCS12) were tested for reliability (internal consistency and test-retest reliability) and validity (construct: convergent and discriminant; criterion: concurrent and predictive). A total of 15,716 patients with NCP were included in the final analysis. The MCS12 and PCS12 demonstrated high internal consistency (Cronbach’s alpha and Mosier’s alpha > 0.8), and moderate and high test-retest reliability, respectively (MCS12 intraclass correlation coefficient (ICC): 0.64; PCS12 ICC: 0.73). Both scales were significantly associated with a number of chronic conditions (p < 0.05). The PCS12 was strongly correlated with perceived health (r = 0.52) but weakly correlated with perceived mental health (r = 0.25). The MCS12 was moderately correlated with perceived mental health (r = 0.42) and perceived health (r = 0.33). Increasing PCS12 and MCS12 scores were significantly associated with lower odds of reporting future physical and cognitive limitations (PCS12: OR = 0.90 95%CI: 0.89–0.90, MCS12: OR = 0.94 95%CI: 0.93–0.94). In summary, the SF-12v2 is a reliable and valid measure of HRQoL for patients with NCP.

Assessment of Reliability and Validity of SF-12v2 among a Diabetic Population

“…Other studies have evaluated the SF-12v2 in different disease populations [8][9][10][11] and found results similar to those reported by Ware et al [6] and Cheak-Zamora et al [7]. Effective use of the instrument in specific disease populations requires thorough psychometric evaluation, which the present studies lack.…”

Reliability and Validity of the Short-Form 12 Item Version 2 (SF−12v2) Health-Related Quality of Life Survey and Disutilities Associated with Relevant Conditions in the U.S. Older Adult Population

“…MCS and PCS were very poorly related with each other. These findings were as expected and similar to those found by previous studies that validated the SF−12v2 using Medical Expenditure Panel Survey data, albeit in different populations [16,18,19]. Thus, the questionnaire demonstrated sufficient convergent and discriminant ability.…”

“…The Medical Expenditure Panel Survey includes the SF−12v2 instrument [10]. Previous studies have used the SF−12v2 instrument to quantify health related quality of life in an older population [11][12][13][14][15] and although this instrument has been validated in other groups [16][17][18][19][20][21], there is a need to validate this instrument among older adults. This study aims to evaluate the psychometric properties of the SF−12v2 among older adults using data from the Medical Expenditure Panel Survey and classical testing methods.…”

Health‐Related Quality of Life among Chronic Opioid Users, Nonchronic Opioid Users, and Nonopioid Users with Chronic Noncancer Pain

“…Validation of the MCS12 in participants with noncancer pain showed a “dose related” decrease with increasing number of chronic conditions, which signifies increasing debility (Hayes et al. ).…”

“…The SF‐12v2 has recently been validated in a noncancer pain cohort in MEPS (Hayes et al. ). PCS12 and MCS12 are collected in round 2 and round 4.…”