Relationship of fatigue and exercise capacity with emotional and physical state in patients with coronary artery disease admitted for rehabilitation program

Fatigue in Patients With Coronary Artery Disease

“…Exercise capacity in patients with CAD is strongly associated with clinical CAD severity markers such as New York Heart Association (NYHA) functional class and demographic factors such as sex, but not with psychologic factors (5). A recent study performed in 240 patients with heart failure reported that, after adjusting for other variables, reduced exercise capacity remained correlated with lower concentrations of free T 3 in patients with severe cardiac impairment (21).…”

“…Instead, fatigue was associated with a variety of negative psychosocial factors such as depression, anxiety, sleep disorders, and type D personality (3,4,5), which are prevalent in patients with CAD and are associated with reduced quality of life and adverse outcomes (6,7).…”

Diagnostic accuracy of self-rating scales for screening of depression in coronary artery disease patients

“…Elevated depressive symptoms are even more prevalent in CAD patients [2,3]. Negative sequelae of depression in CAD patients include increased rates of recurrent ischemic events and death [1], increased probability of negative treatment outcomes [4], worse quality of life [5] and a higher level of fatigue [6].…”

Psychological vulnerability, ventricular tachyarrhythmias and mortality in implantable cardioverter defibrillator patients: is there a link?

“…Evidence suggests that patients with depression also tend to forget or skip their medication more often after adjustment for potential confounding variables, including age, ethnicity, education, social support and measures of cardiac disease severity [69], thereby increasing the risk of arrhythmias and mortality. Similarly, depression has found to be a strong determinant of all dimensions of subjective fatigue in patients with coronary artery disease [70], which may influence patient motivation to engage in exercise [70]. The lack of exercise may also result from anticipatory anxiety, with ICD patients having a restricted lifestyle because of the fear of a shock [71].…”