Relationship between lung function results in the first year of life and respiratory morbidity in early childhood in patients born prematurely

Giffin, F.; Greenough, Anne; Yüksel, B.

doi:10.1002/ppul.1950180505

Cited by 16 publications

(26 citation statements)

References 14 publications

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“…Diminished lung function at that age in premature infants is predictive of ongoing respiratory morbidity. 6 It is therefore important to determine whether these male infants are at increased risk of such morbidity during the preschool years. Values are mean (SD) or mean (95% confidence interval).…”

Section: Discussionmentioning

confidence: 99%

Respiratory function of very prematurely born infants at follow up: influence of sex

Thomas

2005

Archives of Disease in Childhood - Fetal and Neonatal Edition

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Section: Discussionmentioning

confidence: 99%

Respiratory function of very prematurely born infants at follow up: influence of sex

Thomas

2005

Archives of Disease in Childhood - Fetal and Neonatal Edition

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“…Giffin et al 23 observaram que a resistência aérea elevada (≥ 50cmH 2 O/L/s) com um ano de idade foi associada a maior risco de sintomas respiratórios como tosse e/ou sibilos no primeiro, segundo e terceiro anos de vida dos prematuros. Em oposição a esses resultados, a alteração da resistência pulmonar nas crianças acompanhadas na nossa coorte não teve associação com a morbidade respiratória (RT = 0,9; IC95%: 0,7-1,4).…”

Section: Prova De Função Pulmonar Alteradaunclassified

“…Contudo, alteração na complacência pulmonar próximo à alta do berçário aumentou em 60% a taxa de incidência de morbidade respiratória entre 12 e 36 meses, quando comparadas às crianças que apresentaram complacência normal (IC95%: 1,1-2,2). A metodologia empregada por Giffin et al 23 foi diferente da por nós empregada, o que dificulta comparações.…”

Section: Prova De Função Pulmonar Alteradaunclassified

“…Giffin et al 23 observaram 88 crianças prematuras com peso médio ao nascer de 1.248g, acompanhadas até três anos de idade. As crianças foram consideradas sintomáticas quando apresentaram sibilos e/ou tosse por mais de três dias por semana por um período de quatro semanas ou se apresentassem sibilos e/ou tosse por pelo menos três dias após infecção do trato respiratório superior.…”

Section: Sibilos Recorrentesunclassified

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Fatores associados à morbidade respiratória entre 12 e 36 meses de vida de crianças nascidas de muito baixo peso oriundas de uma UTI neonatal pública

et al. 2009

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O objetivo do estudo foi estimar a morbidade respiratória entre 12 e 36 meses em crianças prematuras e identificar os fatores associados. A população compreendeu 84 crianças de uma coorte de prematuros de muito baixo peso. O desfecho foi a taxa de incidência de morbidade respiratória. A associação entre as variáveis independentes e morbidade respiratória foi verificada por modelo linear generalizado. Entre 12 e 24 meses, 56,3% das crianças apresentaram morbidade respiratória. Entre 24 e 36 meses, 38,1% das crianças foram acometidas. As variáveis associadas à morbidade respiratória foram: displasia broncopulmonar (RT = 1,9; IC95%: 1,2-2,9), complacência pulmonar alterada (RT = 1,6; IC95%: 1,1-2,2), pneumonia neonatal (RT = 2,8; IC95%: 2,0-4,0), persistência do canal arterial (RT = 1,6; IC95%: 1,1-2,4) e morbidade respiratória no primeiro ano de vida (RT = 1,8; IC95%: 1,3-2,6). A incidência de morbidade respiratória entre 12 e 36 meses se manteve elevada neste grupo de crianças de alto risco, o que reforça a necessidade de acompanhamento e de intervenções efetivas na prevenção do adoecimento e na melhora da qualidade de vida destas crianças e suas famílias.

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“…Children with a low birthweight are at risk of having narrow airways and/or early respiratory symptoms [56,[84][85][86][87][88], and of developing allergic sensitization or wheeze in early childhood [70,76,78,89,90]. Studies conducted in China, where few women smoke, suggest that the effects of exposure to ETS in infancy are different from those of maternal smoking during pregnancy [54,55].…”

Section: Environmental Tobacco Smokementioning

confidence: 99%

Prevention of asthma

Peat¹

1996

European Respiratory Journal

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Environmental factors which have changed in the last decade or so appear to be largely responsible for the increase in the prevalence of asthma in affluent countries. It should, therefore, be possible to design interventions to reverse these recent trends and reduce the incidence of asthma. Primary preventive strategies have the potential not only to reduce acquisition of sensitization to common allergens and the risk that symptoms will develop subsequently, but also to reduce morbidity in those who already have persistent disease. There is accumulating epidemiological evidence that a dietary exess of sodium and omega-6 fatty acids, a dietary deficiency of antioxidant vitamins and omega-3 fatty acids, reduced rates of breastfeeding and exposure to allergens and environmental tobacco smoke are all involved in the aetiology of asthma. The modification of these factors has the potential to reduce the incidence and thus the prevalence of this disease. Environmental intervention should be particularly effective in children who have inherited or acquired characteristics which put them at high risk of developing asthma. With the evidence now available, it seems reasonable to assume that interventions which are based on our current knowledge of risk factors could achieve a 50% reduction in the prevalence of asthma in the next generation of children. Eur Respir J., 1996; 9, 1545-1555 Environmental factors which have changed in the last two decades appear to be largely responsible for an increased prevalence of asthma in affluent countries [1][2][3][4][5][6]. This implies that it is possible to design interventions to reverse these trends and reduce the incidence of asthma. Primary preventive strategies have the potential to reduce rates of acquisition of sensitization to common allergens and the risk that symptoms will subsequently develop and also to reduce morbidity in those who already have persistent disease. This review examines the evidence that there are avoidable factors which, if modified, have the potential to reduce the incidence and, thus, the prevalence of asthma. Reducing the prevalence of asthmaApplied epidemiological studies can provide a systematic approach to reducing the prevalence of asthma. As many as 25% of children in affluent countries now report that they have wheezed in the last year [7][8][9][10], although only half this number have an asthmatic illness which has clinical importance. Data from studies which have measured the burden and distribution of asthma and which have quantified the aetiological factors can be used to estimate the fraction of illness that is attributable to modifiable risk factors [11], but different types of studies will be needed in the future to estimate the effectiveness and the economic implications of preventive interventions.

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Relationship between lung function results in the first year of life and respiratory morbidity in early childhood in patients born prematurely

Cited by 16 publications

References 14 publications

Respiratory function of very prematurely born infants at follow up: influence of sex

Respiratory function of very prematurely born infants at follow up: influence of sex

Fatores associados à morbidade respiratória entre 12 e 36 meses de vida de crianças nascidas de muito baixo peso oriundas de uma UTI neonatal pública

Prevention of asthma

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