Relationship between human rib mechanical properties and cortical bone density measured by high-resolution quantitative computed tomography

Zhu, Yumin; Fang, Yuan; Bermond, François; Bruyère-Garnier, Karine; Ellouz, Rafaa; Rongièras, Frédéric; Mitton, David

doi:10.1080/10255842.2013.815888

Cited by 5 publications

(10 citation statements)

References 5 publications

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“…Today, quantitative computed tomography is the only clinical modality that could provide a non-invasive estimation of rib mechanical properties based on rib density measurements. This approach relies on the hypothesis that the relationship between bone mineral density (assessed using quantitative computed tomography) and modulus of elasticity, which has been determined for vertebral cancellous bone (Kopperdahl et al 2002) and femoral cortical bone (Duchemin et al 2008)) can be determined for the ribs (Zhu et al 2013). One drawback of this approach is the radiation dose of this imaging modality.…”

Section: Introductionmentioning

confidence: 99%

Non-destructive assessment of human ribs mechanical properties using quantitative ultrasound

Mitton

Minonzio

Talmant

et al. 2014

Journal of Biomechanics

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Advanced finite element models of the thorax have been developed to study, for example, the effects of car crashes. While there is a need for material properties to parameterize such models, specific properties are largely missing. Non-destructive techniques applicable in vivo would, therefore, be of interest to support further development of thorax models. The only non-destructive technique available today to derive rib bone properties would be based on quantitative computed tomography that measures bone mineral density. However, this approach is limited by the radiation dose. Bidirectional ultrasound axial transmission was developed on long bones ex vivo and used to assess in vivo health status of the radius. However, it is currently unknown if the ribs are good candidates for such a measurement. Therefore, the goal of this study is to evaluate the relationship between ex vivo ultrasonic measurements (axial transmission) and the mechanical properties of human ribs to determine if the mechanical properties of the ribs can be quantified non-destructively. The results show statistically significant relationships between the ultrasonic measurements and mechanical properties of the ribs. These results are promising with respect to a non-destructive and non-ionizing assessment of rib mechanical properties. This ex vivo study is a first step toward in vivo studies to derive subject-specific rib properties.

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Section: Introductionmentioning

confidence: 99%

Non-destructive assessment of human ribs mechanical properties using quantitative ultrasound

Mitton

Minonzio

Talmant

et al. 2014

Journal of Biomechanics

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“…The proposed methodology is based on the fact that BMD was shown to be a good predictor of elasticity for human cortical bones, assessed by either clinical QCT [ 22 ] or HR-pQCT [ 31 ]. HR-pQCT can provide high-quality images with clear cortical edges, resulting in accurate BMD measurements.…”

Section: Discussionmentioning

confidence: 99%

“…The elasticity ( E ) of the child rib cortical bones was estimated based on the regression presented in [ 31 ] on the adult rib (cortical bone) and recalled below:

where BMD HR was measured by HR-pQCT and reported in mg HA/cm 3 and the elasticity was assessed using three-point bending tests and an inverse approach [ 13 ]. The data for these adult ribs are given in Table 2 .…”

Section: Methodsmentioning

confidence: 99%

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In Vivo Assessment of Elasticity of Child Rib Cortical Bone Using Quantitative Computed Tomography

Zhu

Bermond

Garanderie

et al. 2017

Applied Bionics and Biomechanics

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Elasticity of the child rib cortical bone is poorly known due to the difficulties in obtaining specimens to perform conventional tests. It was shown on the femoral cortical bone that elasticity is strongly correlated with density for both children and adults through a unique relationship. Thus, it is assumed that the relationships between the elasticity and density of adult rib cortical bones could be expanded to include that of children. This study estimated in vivo the elasticity of the child rib cortical bone using quantitative computed tomography (QCT). Twenty-eight children (from 1 to 18 y.o.) were considered. Calibrated QCT images were prescribed for various thoracic pathologies. The Hounsfield units were converted to bone mineral density (BMD). A relationship between the BMD and the elasticity of the rib cortical bone was applied to estimate the elasticity of children's ribs in vivo. The estimated elasticity increases with growth (7.1 ± 2.5 GPa at 1 y.o. up to 11.6 ± 1.9 GPa at 18 y.o.). This data is in agreement with the few previous values obtained using direct measurements. This methodology paves the way for in vivo assessment of the elasticity of the child cortical bone based on calibrated QCT images.

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“…Thus, the appearance of precipitation phases in the austenite of SS316L should be limited. Zhu et al reported that the density of the human rib is 0.736 g/cm 3 [14]. The Young's modulus of the rib under flexural condition is 2.79 to 7.44 GPa [1].…”

Section: Introductionmentioning

confidence: 99%

Selective Laser Melting of Stainless Steel 316L with Face-Centered-Cubic-Based Lattice Structures to Produce Rib Implants

2021

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Selective laser melting has a great potential to manufacture biocompatible metal alloy scaffolds or implants with a regulated porosity structure. This study uses five face-centered cubic (FCC) lattice structures, including FCC, FCC-Z, S-FCC, S-FCC-Z, and FCC-XYZ. Specimens with different lattice structures are fabricated using two laser energy densities, 71 J/mm3 and 125 J/mm3. Density, tensile, compressive and flexural test results exhibit the effect of laser parameters and lattice structure geometries on mechanical properties. The higher laser energy density of 125 J/mm3 results in higher properties such as density, strength, and Young’s modulus than the laser energy density of 71 J/mm3. The S-FCC lattice has the lowest density among all lattices. The mechanical tests result show specimen with FCC-XYZ lattice structures fabricated using a laser energy density of 125 J/mm3 meet the tensile properties requirement for human ribs. This structure also meets the requirement in flexural strength performance, but its stiffness is over that of human ribs. The compression test results of lattices are still incomparable due to unavailable compression data of the human ribs. In short, The FCC-XYZ lattice design fabricated by the 125 J/mm3 laser energy density parameter can be used to manufacture customized rib implants.

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Relationship between human rib mechanical properties and cortical bone density measured by high-resolution quantitative computed tomography

Cited by 5 publications

References 5 publications

Non-destructive assessment of human ribs mechanical properties using quantitative ultrasound

Non-destructive assessment of human ribs mechanical properties using quantitative ultrasound

In Vivo Assessment of Elasticity of Child Rib Cortical Bone Using Quantitative Computed Tomography

Selective Laser Melting of Stainless Steel 316L with Face-Centered-Cubic-Based Lattice Structures to Produce Rib Implants

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