Relationship between adherence to anti-diabetic medication and depression among patients with diabetes mellitus in three selected Chinese hospitals

Abstract

Purpose: To determine the relationship between adherence to anti-diabetic medication and depression among patients with diabetes mellitus in three hospitals in Chinese.Methods: This research utilized a quantitative and descriptive design, and included 200 diabetic patients who fulfilled the inclusion criteria for recruitment through a convenient sampling technique. The study applied Beck’s depression inventory II scale for assessment of depression, and a questionnaire for adherence to anti-diabetic medication.Results: A total of 64 (32 %) participants had diabetes for 6 to 10 years. There was a high level of adherence to anti-diabetic medication in 96 patients (48 %); 74 participants (37 %) had moderate adherence to anti-diabetic medication, while 30 patients (15 %) had low adherence. A majority of the patients (181, 90.5 %) had no depression. Six (6) patients (3 %) had mild mood disturbance, 2 patients (1 %) had borderline clinical depression, while 11patients (5.5 %) experienced moderate depression.Adherence to anti-diabetic medication was not associated with depression (p = 0.068). However, depression was associated with age ˃ 50 years (p = 0.041), female sex (p = 0.043), long duration of illness (> 5-years) (p = 0.048), and presence of one or more comorbidities (p = 0.049).Conclusion: There was no association between adherence to anti-diabetic medication and depression among diabetic patients.
 Keywords: Adherence to anti-diabetic medication, Beck’s depression inventory II, Depression, Diabetes mellitus

Effect and safety of combined Gegen Qinlian decoction/metformin in the treatment of diabetes mellitus in patients, and its influence on serum C peptide and glycosylated hemoglobin

“…Patients with diabetes mellitus (DM) present with abnormal blood glucose and long-term organ damage, leading to cardiovascular diseases and increasing the disease-associated burden [1][2][3]. Therefore, early diagnosis and treatment should be carried out to strictly control the occurrence of DM.…”

25-Hydroxyvitamin D: A potential marker of the incidence of osteoporosis and sarcopenia in diabetic mellitus patients

“…Normal levels of insulin have an inhibitory effect on protein catabolism in skeletal muscle. Clinical practice shows that most elderly patients with DM are in a state of skeletal muscle dystrophy, which may be related to abnormally elevated blood glucose levels, declining muscle strength, muscle mass, and muscle function [3]. The incidence of sarcopenia in DM patients over 60 years old is about 3 times as high as that in non-DM patients, suggesting a close relationship between DM and the development of sarcopenia [4].…”

Effect of low molecular weight heparin and ulinastatin as a combined therapy on soluble myeloid cell expression and intestinal mucosal function in patients with severe pancreatitis

“…Normal levels of insulin have an inhibitory effect on protein catabolism in skeletal muscle. Clinical practice shows that most elderly patients with DM are in a state of skeletal muscle dystrophy, which may be related to abnormally elevated blood glucose levels, declining muscle strength, muscle mass, and muscle function [3]. The incidence of sarcopenia in DM patients over 60 years old is about 3 times as high as that in non-DM patients, suggesting a close relationship between DM and the development of sarcopenia [4].…”