Regulation of spermatogonia

Zhou, Qing; Griswold, Michael D.

doi:10.3824/stembook.1.7.1

Cited by 7 publications

(16 citation statements)

References 87 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One study [23] got 2 points; 8 studies [16, 19, 20, 24, 28, 30, 34, 35] got 3 points; 11 studies [18, 21, 22, 25–27, 29, 32, 33, 36, 37] got 4 points; one study [15] got 5 points; 3 studies [17, 31, 38] got 6 points; one study [14] got 7 points (Table 1). The average score was 4.00.…”

Section: Resultsmentioning

confidence: 99%

“…Eight studies were online Master's thesis or Ph.D. thesis and not formally published. Seven unpublished Master's theses were from Zhou 2008, Xue 2012, Wang 2013, Wang 2015, Min 2015, Qin 2016, and Zhang 2011 [18, 19, 22, 25, 32, 36, 37]. One unpublished Ph.D. thesis was from Liu 2011 [23].…”

Section: Resultsmentioning

confidence: 99%

“…One study described the sample size calculation [14]. Eleven studies reported compliance with animal welfare regulations [14–18, 25, 31, 32, 36–38]. Fifteen studies mentioned statement of potential conflict of interests [14, 15, 17–19, 22–25, 31, 32, 35–38].…”

Section: Resultsmentioning

confidence: 99%

“…Nineteen out of the 25 studies utilized permanent MCAO models, and the remaining six studies [14, 21–23, 25, 26] were temporary MCAO models in which ischemic time varied from 1 to 2 hours. Fifteen studies utilized a dose gradient of catalpol: six studies [23, 27–30, 35] administrated 15, 30, and 60 mg kg −1 intragastrically, four studies [18, 24, 25, 31] used 1, 5, and 10 mg kg −1 intraperitoneally, two studies [21, 22] used 1 and 5 mg kg −1 intraperitoneally, one study [32] used 1, 3, and 5 mg kg −1 intraperitoneally, one study [36] used 5 and 10 mg kg −1 intraperitoneally, and one study [18] used 1.42, 7, and 14.2 mg kg −1 intraperitoneally. Twenty-three studies administrated catalpol after stroke; one study administrated catalpol before stroke [14]; and two studies administrated catalpol before and after stroke [18, 25].…”

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Neuroprotection of Catalpol for Experimental Acute Focal Ischemic Stroke: Preclinical Evidence and Possible Mechanisms of Antioxidation, Anti‐Inflammation, and Antiapoptosis

Zheng

Yang

Chen

et al. 2017

Oxidative Medicine and Cellular Longevity

View full text Add to dashboard Cite

Neuroprotection is defined as using a therapy that affects the brain tissue in the still-viable ischemic penumbra to salvage or delay the infarction. Catalpol, the main active principle of the root of Radix Rehmanniae, was reported to have pleiotropic neuroprotective effects in neurodegenerative diseases including ischemic stroke. Here, we evaluated the neuroprotective effects of catalpol in experimental acute ischemic stroke. Studies on catalpol in animal models of acute ischemic stroke were identified from 6 databases. Twenty-five studies involving 805 animals were included. Twelve comparisons showed significant effects of catalpol on decreasing infarct size according to 2,3,5-triphenyltetrazolium chloride staining compared with the control (P < 0.05). One study reported significant effect of catalpol on reducing infarct size according to magnetic resonance imaging scan compared with the control (P < 0.05). Meta-analysis of these studies indicated that catalpol significantly improved the neurological function score according to Zea Longa score, Bederson score, balance beam-walking test, adhesive removal test, bar-grasping score, and corner test compared with the control (P < 0.05). In conclusion, catalpol exerted neuroprotective effects for experimental acute focal ischemic stroke, largely through reducing oxidative reactions, inhibiting apoptosis, and repressing inflammatory reactions and autophagy. However, these apparently positive findings should be interpreted with caution because of the methodological flaws.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Neuroprotection of Catalpol for Experimental Acute Focal Ischemic Stroke: Preclinical Evidence and Possible Mechanisms of Antioxidation, Anti‐Inflammation, and Antiapoptosis

Zheng

Yang

Chen

et al. 2017

Oxidative Medicine and Cellular Longevity

View full text Add to dashboard Cite

show abstract

“…Such a new observation system should stimulate understanding of dynamic feature of male meiosis in Drosophila. As a series of cellular events such as cell division, growth, elongation and differentiation in spermatogenesis is considerably conserved between Drosophila and mammals (Zhou and Griswold, 2008), we expect that Drosophila data would also bring us valuable information to help better understanding of mammalian spermatogenesis.…”

Section: Future Researchesmentioning

confidence: 99%