Regulation of fat metabolism during resistance exercise in sedentary lean and obese men

Ormsbee, Michael J.; Choi, Myung Dong; Medlin, Justin K.; Geyer, G; Trantham, Lauren H.; Dubis, Gabriel S.; Hickner, Robert C.

doi:10.1152/japplphysiol.91485.2008

Cited by 63 publications

(62 citation statements)

References 54 publications

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“…1), Ormsbee et al (43) recently reported that lean, but not obese, men had higher serum levels of iGH after a bout of RE consisting of 2 sets of 10 repetitions and a third set to muscular exhaustion employing a load equaling 85% of the individual's established 10 RM. Since neuromuscular recruitment during RE may be a factor influencing GH secretion (7) and since activation of even small muscle groups results in marked increases in GH release (29), we suggest that the exercise protocol used by Ormsbee et al was not sufficient to cause a GH response in the obese participants.…”

Section: Discussionmentioning

confidence: 99%

“…Blood samples were collected at six time points: preexercise, midexercise, immediately postexercise, and 50, 70, 110 min postexercise. Time points were chosen to correspond to differences identified in prior studies (43). The cannula was kept patent with a 10% heparin solution injection.…”

Section: Methodsmentioning

confidence: 99%

“…It is also well established that increased body fat and body mass index (BMI) suppress spontaneous and stimulated serum GH concentrations but that these pulsatile responses return to normal with reduction to normal levels of body weight (43,46). Normal GH response to physiological stimuli such as sleep and cardiovascular exercise appears to be impaired in obese individuals (44).…”

mentioning

confidence: 99%

“…In addition, in response to a cardiovascular exercise stimulus, it has been prolifically established that obese individuals' concentrations are blunted (17). However, only one prior study has examined immunoreactive GH (iGH; i.e., assays that use an antibody-based detection system) response to RE in obese individuals (43). It is important to point out that our understanding of the concentrations of GH variants stimulated by exercise has developed primarily through the use of immunoassays (enzyme immunoassay and RIA), which present an incomplete picture of the GH response to exercise (21).…”

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confidence: 99%

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Immunoreactive and bioactive growth hormone responses to resistance exercise in men who are lean or obese

Thomas

Kraemer

Kennett

et al. 2011

Journal of Applied Physiology

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The present study was designed to examine the effects of a highvolume, whole body acute resistance exercise (RE) protocol on immunoreactive GH (iGH), bioactive GH (bGH), and GH-binding protein (GHBP) in sedentary lean and obese men. Nine obese (mean Ϯ SD: 20.8 Ϯ 2.1 yr old, 177.0 Ϯ 4.1 cm height, 108.7 Ϯ 15.9 kg body mass, 37.6 Ϯ 5.29% body fat) and nine lean (20.1 Ϯ 2.1 yr old, 177.8 Ϯ 8.7 cm height, 71.7 Ϯ 5.8 kg body mass, 14.7 Ϯ 3.54% body fat) men completed an acute RE protocol (6 exercises, 3 sets of 10 repetitions at 85-95% of 10 repetitions maximum with 120-and 90-s rest periods), and blood samples were collected before, at the midpoint, and immediately after exercise and during recovery (ϩ50, ϩ70, and ϩ110). In contrast to prior studies, which examined acute responses to cardiovascular exercise protocols, groups did not differ in iGH response to the exercise stimulus. However, bGH concentrations overall were significantly lower in the obese than the lean participants (P Ͻ 0.001). Additionally, obese individuals had significantly higher GHBP concentrations (P Ͻ 0.001). Results suggest that obese and lean sedentary men performing a high-volume, whole body acute RE protocol demonstrate similar increases in iGH. Blunted bGH and elevated GHBP concentrations are indicative of altered GH activity associated with obesity. Prior research findings of blunted iGH response may be attributable to RE protocols not equated on relative intensity or volume. These results underscore the complexity of pituitary biology and its related mechanisms and may have implications for exercise prescription in the treatment of obesity.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Immunoreactive and bioactive growth hormone responses to resistance exercise in men who are lean or obese

Thomas

Kraemer

Kennett

et al. 2011

Journal of Applied Physiology

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“…Tradicionalmente, o LL tem sido identificado em diferentes tipos de exercícios, especialmente de características cíclicas 5 , e mais recentemente no exercício resistido (ER), com grande validade ecológica, por ser amplamente empregado na avaliação e prescrição do exercício no treinamento atlético e na reabilitação física 6 , visando benefícios cardiovasculares 7 , neuromusculares 8 e metabólicos 9 . No entanto, sua prescrição utiliza-se basicamente de métodos tradicionais para avaliação e acompanhamento da evolução no treinamento físico.…”

Section: Resumen Introducción: El Umbral Anaeróbico Se Identifica Comunclassified

Limiar Anaeróbio a Partir Da Pse Em Exercício Resistido Por Modelos Matemáticos

Arsa

Cambri

Silva

et al. 2016

Rev Bras Med Esporte

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reSUmoIntrodução: O limiar anaeróbio é comumente identificado em exercícios cíclicos, contudo, também pode ser determinado no exercício resistido (ER) por diferentes métodos, e assim, estimar a carga de trabalho relacionada ao estresse metabólico. No entanto, sua identificação a partir de outros métodos como o modelo matemático da DMáx e principalmente por variáveis mais acessíveis, como a percepção subjetiva de esforço (PSE), ainda não foi analisada. Objetivo: Comparar o limiar de lactato (LL) identificado pelo método de inspeção visual (LL IV ) com o método da DMáx aplicado nas respostas do lactato (LL DMáx ) e da PSE (PSE 12/13 e PSE DMáx ) durante exercício resistido incremental. Métodos: Dez praticantes de ER (24,8 ± 3,0 anos) foram submetidos ao teste de uma repetição máxima (1-RM) e a um teste incremental no leg-press, obtendo-se a PSE e o lactato em cada estágio. Resultados: Foi possível identificar o limiar anaeróbio por todos os métodos, entre 30% a 40% de 1-RM. As cargas absolutas, concentrações de lactato sanguíneo e PSE não foram diferentes entre os métodos empregados e apresentaram boa concordância entre si. Conclusão: É possível identificar o limiar anaeróbio tanto por inspeção visual quanto pelo modelo matemático de DMáx para o lactato e PSE, ampliando as possibilidades de determinação do limiar anaeróbio no exercício resistido por métodos de baixo custo e não invasivos.descritores: limiar anaeróbio; esforço físico; treinamento de resistência. ABSTRACT introduction: the anaerobic threshold is commonly identified in cyclic exercises, however it can also be identified on resistance exercise (re) by different methods, and thus can estimate the workload related to metabolic stress. however, its identification by other methods such as mathematical model of dmax and primarily by more accessible variables such as perceived exertion (Pe) has not yet been analyzed. objective: to compare the lactate threshold (lt) identified by visual inspection method (lt

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Full‐body resistance training promotes greater fat mass loss than a split‐body routine in well‐trained males: A randomized trial

Carneiro,

Nunes,

Souza

et al. 2024

European Journal of Sport Science

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While significant progress has been made in understanding the resistance training (RT) strategy for muscle hypertrophy increase, there remains limited knowledge about its impact on fat mass loss. This study aimed to investigate whether full‐body is superior to split‐body routine in promoting fat mass loss among well‐trained males. Twenty‐three participants were randomly assigned to 1 of 2 groups: full‐body (n = 11, training muscle groups 5 days per week) and split‐body (n = 12, training muscle groups 1 day per week). Both groups performed a weekly set volume‐matched condition (75 sets/week, 8–12 repetition maximum at 70%–80 % of 1RM) for 8 weeks, 5 days per week with differences only in the routine. Whole‐body and regional fat were assessed using DXA at the beginning and at the end of the study. Full‐body RT elicited greater losses compared to split‐body in whole‐body fat mass (−0.775 ± 1.120 kg vs. +0.317 ± 1.260 kg; p = 0.040), upper‐limb fat mass (−0.085 ± 0.118 kg vs. +0.066 ± 0.162 kg; p = 0.019), gynoid fat mass (−0.142 ± 0.230 kg vs. +0.123 ± 0.230 kg; p = 0.012), lower‐limb fat mass (−0.197 ± 0.204 kg vs. +0.055 ± 0.328 kg; p = 0.040), and a trend in interaction in android fat mass (−0.116 ± 0.153 kg vs. +0.026 ± 0.174 kg; p = 0.051), with large effects sizes (η2p ≥ 0.17). This study provides evidence that full‐body is more effective in reducing whole‐body and regional fat mass compared to split‐body routine in well‐trained males.

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Regulation of fat metabolism during resistance exercise in sedentary lean and obese men

Cited by 63 publications

References 54 publications

Immunoreactive and bioactive growth hormone responses to resistance exercise in men who are lean or obese

Immunoreactive and bioactive growth hormone responses to resistance exercise in men who are lean or obese

Limiar Anaeróbio a Partir Da Pse Em Exercício Resistido Por Modelos Matemáticos

Full‐body resistance training promotes greater fat mass loss than a split‐body routine in well‐trained males: A randomized trial

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