Analysis with liquid scintillation spectrometry of extracts from red oak (Quercus rubra L.) injected with 14C-l,2-dihydro-3, 6-pyridazinedione (Maleic hydrazide or MH) or 14C-butanedioic acid mono-(2,2-dimethylhydrazide) (daminozide) indicated that both growth inhibitors were distributed acropetally as well as basipetally over a 22 day period. Acropetal movement however, was slower with 14C-MH than with 14C-daminozide. Between 3 and 22 days after injection, about 20% of the 14C was lost from plants treated with 14C-daminozide. Ionexchange and thin-layer chromatographic techniques showed that daminozide did not form any detectable metabolites, while MH formed a conjugate with glucose. With both chemicals 12 to 15% of the radioactivity was present in the bound form after 22 days and exudation of 14C from the roots was not detected.