Regional transport, source apportionment and health impact of PM10 bound polycyclic aromatic hydrocarbons in Singapore's atmosphere

Urbančok, Dejan; Payne, Anthony John Ramsay J. R.; Webster, Richard D.

doi:10.1016/j.envpol.2017.07.086

Cited by 62 publications

(35 citation statements)

References 73 publications

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“…Several studies have investigated the effects of oral arsenic exposure on health [2,3]. In recent years, many cities in China have been exposed to a continuous haze that directly affects human health and travel safety [4,5]. The main pollutant present in this haze is fine particulate matter (PM 2.5 ), and analysis of the composition of PM 2.5 identified that arsenic is one of the major pollutants [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Hematotoxicity of intratracheally instilled arsenic trioxide in rats

Su¹,

Sun²,

Wang³

et al. 2018

Infection International

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The study aimed to investigate the correlation between concentration of inhaled arsenic trioxide and dynamic changes in hematotoxicity in rats. Wistar rats were randomly divided into four study groups that were treated with saline (control) or arsenic trioxide at a low (0.1 mg/mL), medium (1 mg/mL), or high (10 mg/mL) dose by intratracheal instillation. Blood samples were collected for analysis at 6, 12, 24, 48, and 72 h after exposure. Compared with the control group, intratracheal instillation of arsenic trioxide affected hematopoietic differentiation in rats, leading to blood cell changes that were related to observation time and concentration.

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Section: Introductionmentioning

confidence: 99%

Hematotoxicity of intratracheally instilled arsenic trioxide in rats

Su¹,

Sun²,

Wang³

et al. 2018

Infection International

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“…The PSI reflects the most abundant pollutant found in the atmosphere during a haze episode which is PM 10 , and much of PM 10 comprises PM 2.5 . 35,48 The concentration of PM 10 is also consistently low with little variations in the absence of haze, but increased significantly during episodes of transboundary haze; 49 consequently, the results of this study largely reflected the effect of PM.…”

Section: Discussionmentioning

confidence: 59%

Impact of Air Pollution and Trans-Boundary Haze on Nation-Wide Emergency Department Visits and Hospital Admissions in Singapore

Chan

Ding

et al. 2020

Ann Acad Med Singap

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Introduction: Air pollution is associated with adverse health outcomes. However, its impact on emergency health services is less well understood. We investigated the impact of air pollution on nation-wide emergency department (ED) visits and hospital admissions to public hospitals in Singapore. Materials and Methods: Anonymised administrative and clinical data of all ED visits to public hospitals in Singapore from January 2010 to December 2015 were retrieved and analysed. Primary and secondary outcomes were defined as ED visits and hospital admissions, respectively. Conditional Poisson regression was used to model the effect of Pollutant Standards Index (PSI) on each outcome. Both outcomes were stratified according to subgroups defined a priori based on age, diagnosis, gender, patient acuity and time of day. Results: There were 5,791,945 ED visits, of which 1,552,187 resulted in hospital admissions. No significant association between PSI and total ED visits (Relative risk [RR], 1.002; 99.2% confidence interval [CI], 0.995–1.008; P = 0.509) or hospital admissions (RR, 1.005; 99.2% CI, 0.996–1.014; P = 0.112) was found. However, for every 30-unit increase in PSI, significant increases in ED visits (RR, 1.023; 99.2% CI, 1.011–1.036; P = 1.24 × 10˗6) and hospital admissions (RR, 1.027; 99.2% CI, 1.010–1.043; P = 2.02 × 10˗5) for respiratory conditions were found. Conclusion: Increased PSI was not associated with increase in total ED visits and hospital admissions, but was associated with increased ED visits and hospital admissions for respiratory conditions in Singapore. Key words: Epidemiology, Healthcare utilisation, PSI, Public health, Time series

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“…Cancer risk from PAHs exposure can be calculated by the inhalation cancer risk (ICR) [32]. The values in this study was 1.0×10 -4 , indicated high potential health risk [43][44]. It implied that, 10 of 100,000 people may be at risk of developing cancer if they exposed to these pollutants for 70 years.…”

Section: ) Health Risk Assessment Of Pahsmentioning

confidence: 72%

Characterization of PM2.5–bound Polycyclic Aromatic Hydrocarbons in Chiang Mai, Thailand during Biomass Open Burning Period of 2016

Thepnuan

Chantara

2020

App. Envi. Res.

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Polycyclic aromatic hydrocarbons (PAHs) bounded to ambient fine particles (PM2.5) were determined for enabling health risk assessment and source identification of ambient aerosols. Daily PM2.5 samples (24 h) were collected on quartz fiber filters by using a low volume air sampler (16.7 L min-1) during smoke haze period (March–April 2016) in Chiang Mai, Thailand. An average concentration of PM2.5 (n=54) was 65.3±17.6 μg m-3. The samples were extracted with dichloromethane using ultrasonication prior to PAHs analysis by GC-MS. Average concentrations of 16-PAHs, non-carcinogenic (nc) PAHs and carcinogenic (c) PAHs were 10.23±2.49, 5.48±1.70 and 4.75±1.43 ng m-3, respectively. Ratio values of cPAHs/ncPAHs ranged from 0.44 to 1.98. Strong correlation (r= 0.76) between PM2.5 and cPAHs concentration was observed. Toxicity equivalent concentrations (TEQ) of PAHs was 1.13±0.34 ng m-3. The value of inhalation cancer risk (ICR) for exposure of ambient PAHs calculated from TEQ value was 1.0×10-4 indicating high risk for long term exposure. Diagnostic ratios (DRs) of various pairs of PAHs revealed that biomass burning is a major source during smoke haze period.

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Regional transport, source apportionment and health impact of PM10 bound polycyclic aromatic hydrocarbons in Singapore's atmosphere

Cited by 62 publications

References 73 publications

Hematotoxicity of intratracheally instilled arsenic trioxide in rats

Hematotoxicity of intratracheally instilled arsenic trioxide in rats

Impact of Air Pollution and Trans-Boundary Haze on Nation-Wide Emergency Department Visits and Hospital Admissions in Singapore

Characterization of PM2.5–bound Polycyclic Aromatic Hydrocarbons in Chiang Mai, Thailand during Biomass Open Burning Period of 2016

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