Recurrent herpes simplex infections: laser therapy as a potential tool for long-term successful treatment

Abstract

Herpes simplex virus types 1 and 2 are the main infectious agents associated with oral and genital ulcerations. These infections are now widely recognized as sexually transmitted diseases. Among treatment options, low-level laser therapy (LLLT) has shown promising clinical results as a longer-lasting suppression therapy. Two clinical cases are described with recurrent labial herpes for which LLLT was used. Following treatment, both patients remained symptom free during the 17-month clinical follow-up period. Keywords: Low-level laser therapy. Herpes simplex type 1. Herpes simplex type 2. RESUMOOs vírus do herpes simplex tipos 1 e 2 são os principais agentes infecciosos associados às ulcerações orais e vaginais. Estas infecções são amplamente reconhecidas como doenças sexualmente transmissíveis. Entre as opções de tratamento, o laser de baixa intensidade (LBI) mostrou resultados promissores como terapia de supressão de longa duração. Descrevemos dois casos clínicos com herpes labial recorrentes nos quais o LBI foi utilizado que permaneceram assintomáticos durante 17 meses de controle clínico. Palavras-chaves: Laser de baixa intensidade. Herpes simplex tipo 1. Herpes simplex tipo 2.

Applications of Low Level Laser Therapy

“…There were no significant side effects and herpetic lesions healed faster. Carvalho-Ferreira et al [13] described two patients with herpetic infection who were treated five times with laser (660 nm wavelength, 30J/cm² of continuous mode and power density of 100mW which was applied for 8 seconds). Remission occurred after five days without reoccurrences during the next 17 months in both patients.…”

Infecções por herpes vírus tipos 1/2: avaliação de vídeos on line

“…7 It is understood that sun exposure, sleep quality associated with stress, depression and/or sadness, as well as deficient feeding, can be factors that decrease the resistance of the immune system, which can trigger the activation of HSV-1 and consequently , to promote the development of lesions associated with it. 8 Although there are many measures to prevent HSV, educational and counseling measures are still fundamental. It is estimated that a reduction of about 50% in HSV-2 is associated with the simple use of a barrier method, such as the male condom.…”

“…Stress, sleep pattern and sun exposure were also factors associated with the development of lesions, as well as in other studies, since, besides being included in prevention, they are triggers for the development of infection. 8 There is little information on nutritional information (15.8%), although good nutrition can be considered an important factor in the prevention of infection. 8 In the study, there was a considerable increase in videos posted on HSV-1 and HSV-2, probably due to the greater number of accesses to the virtual media and/or platforms, as well as health promotion and education events with the dissemination of new possibilities for obtaining information and raising awareness through the Internet.…”

“…8 There is little information on nutritional information (15.8%), although good nutrition can be considered an important factor in the prevention of infection. 8 In the study, there was a considerable increase in videos posted on HSV-1 and HSV-2, probably due to the greater number of accesses to the virtual media and/or platforms, as well as health promotion and education events with the dissemination of new possibilities for obtaining information and raising awareness through the Internet. It is of the utmost importance, as the subject matter is related to public health, to understand how information is transmitted and to follow the advances in communication, since the media has a fundamental role in this process, generating benefits to the population with interdisciplinary information in health, and can influence the public in a negative or positive way.…”

Estudo clínico, bioquímico e histológico do efeito da terapia fotodinâmica na mucosite oral induzida por 5-Fluorouracil em hamsters

“…Já a emissão da luz vermelha é mais utilizada quando as estruturas a serem alcançadas são mais superficiais, como epitélio e lâmina própria de tecido conjuntivo. Essa luz é bastante empregada para casos em que o objetivo principal é a reparação tecidual (Kreisler et al, 2001;Simões et al, 2009b), como herpes simples (Simões et al, 2009b;Ferreira et al, 2011;MuñozSanchez et al, 2012) e ulcerações em geral (de Melo Rambo et al, 2014;Kilík et al, 2014).…”