Recurrent erythema multiforme: Clinical characteristics, etiologic associations, and treatment in a series of 48 patients at Mayo Clinic, 2000 to 2007

Erythema and Acute Pain in the Hands

“…Itching, burning, swelling, pain, and post-inflammatory hyperpigmentation [2] are also described as part of the sequelae of EM. Recurrent EM (greater than six times per year) and persistent [1,5,6] EM have been described. EM is a clinical diagnosis for which there is no lab test.…”

“…Symptomatic treatment using antihistamines and topical steroids is warranted [2]. Treatment with antibiotics and possibly hospital admission are recommended if the underlying source is Mycoplasma pneumoniae infection [1,2,6]. A brief description EM as well as the other answer choices can be found in Table 1.…”

Clinical characteristics and causes of erythema exsudativum multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis

“…A legtöbb publikáció szerint az EEM eseteiben enyhe férfi túlsúly figyelhetô meg (kivéve a recidiváló megjelenést, ott enyhe nôi dominanciáról számoltak be) (2,7,11). Eredményeink szerint a betegek kétharmada (68,9%) nô volt.…”

“…A recidiváló EEM hátterében legtöbbször HSV áll, még nagyobb arányban, mint a nem ismétlôdô eseteknél, 61-100%-ban ez a vírus felelôs az ismétlôdô esetekért (11). Ennek megfelelô eredményt lehetett az általunk vizsgált betegcsoportnál is megfigyelni, a betegek 61,9%-nál HSV fertôzés provokálta a tüneteket.…”

Erythema multiforme associated with herpes labialis

“…1 Other known associations with recurrent erythema mul ti forme include complex aphthosis, bacterial infection (e.g., Mycoplasma pneumonia), ad verse drug reactions and menstruation. 1,2 The lesions of recurrent erythema multiforme typically resolve in 1-2 weeks and are selflimited. When associated with herpes simplex virus, the duration of episodes can vary in the same patient and are directly related to intralesional expression of viral genes.…”