Erythema multiforme associated with herpes labialis

Abstract

A 35-year-old woman presented to the emergency department with a recurrent rash on the backs of both hands related to what she described as a "fever blister" on her lower lip. In the previous 2 years, she had experienced more than 12 similar eruptions involving both her lip and hands. She was not taking any medications. On examination, the centre of the vesicle on the patient's lip was yellowish, and the backs of both hands showed red papules and some red plaques with necrotic centres, consistent with target lesions (Figure 1). We diagnosed erythema multiforme secondary to recur rent herpes labialis.Erythema multiforme is a self-limited hypersensitivity reaction involving both skin and mucous membranes. The most common condition

Effectiveness of Topical Steroids in Treating Herpes-Associated Erythema Multiforme and Review of Topical Steroids Erythema Multiforme and Review of Topical St

“…More than half of the patients did not have an identifiable cause for recurrent EM, and the frequency of a diagnosis of HSV associated with HAEM varies between studies. 13,14 When target lesions are not present, the diagnosis of EM is very difficult. For more severe cases of EM, supportive care and treatment with systemic steroids or other immunosuppressive agents are necessary.…”