Recidivas e recorrências de carcinomas basocelulares da face

Basal cell carcinoma is the most common skin cancer in the world. The aim of this study was to evaluate the surgical margin of basal cell carcinoma and correlate this with its histologic subtype. A retrospective analysis of pathology laboratory records from 1990 to 2000 was performed and the following data was collected: age, sex, race, anatomical location, histological type, and state of the excision margins in 1,428 histopathological reports of basal cell carcinoma. Ages ranged from 6 to 99 years, with an average of 57. There was a slight predominance of lesions in white women patients, and the most common histological subtype was the nodular, followed by the superficial. The most common locations were in the head and neck, with highest prevalence appeared in the nose. Surgical margins revealed a lateral involvement of 20.14% and a deep involvement of 12.47%. The fibrosing basal cell carcinoma is the histological type that most often presented positive surgical margins.

Section: Discussionmentioning

confidence: 99%

Evaluation of surgical margins according to the histological type of basal cell carcinoma

Godoy

Neta

Leão

et al. 2017

“…Basal cell carcinoma (BCC) is the most common malignancy among men, and its incidence is on the rise in several countries. 1 - 3 At Faculdade de Medicina de Botucatu-SP (Brazil) more than 900 patients are operated a year.…”

Section: Introductionmentioning

confidence: 99%

Nuclear morphometry and chromatin textural characteristics of basal cell carcinoma

Mendaçolli

Brianezi

Schmitt

et al. 2015

Self Cite

Histological subtypes of basal cell carcinoma have biological, evolutionary and distinct prognostic behavior. The analysis of characteristics of the nucleus can provide data on their cellular physiology and behavior. The authors of this study evaluated nuclear morphological parameters and textural patterns of chromatin from different subtypes of basal cell carcinoma: nodular (n=37), superficial (n=28) and sclerodermiform (n=28). The parameters were compared between neoplasms' subtypes and with unaffected adjacent basal epithelium. Nuclear area and diameter of sclerodermiform neoplasms were superior to the other subtypes. Chromatin's color intensity and fractal dimension were less intense in superficial subtypes. Nuclear roundness and chromatin's entropy presented lower values in tumors than in normal epithelium. There was significant correlation between morphological and textural variables of normal skin and tumors. Morphometric elements and textural chromatin's homogeneity of basal cell carcinomas may be related to evolutionary, biological and behavior particularities related to each histotype.

“…On the other hand, incomplete excisions are charged with changing the tumor structure, thus generating a more aggressive behavior. 7,8 Sartore et al reports that 5 to 50% of BCC are incompletely excised. 7,9 …”

Section: Introductionmentioning

confidence: 99%

High-frequency ultrasound associated with dermoscopy in pre-operative evaluation of basal cell carcinoma

Barcaui

Carvalho

Valiante

et al. 2014

The recent development of high-frequency ultrasound, associated with the improved sensitivity in color Doppler, enabled the identification of various skin structures and layers. In basal cell carcinoma, the 22 MHz frequency ultrasound permits the delimitation of tumor margins, while color Doppler, determines its vascularization. We present two cases in which the association of both exams allowed an in vivo analysis of the tumor's morphology, size, thickness and vascularization, thus contributing to a better pre-operative evaluation.