Recent increase in measles in children and teenagers in Switzerland

Richard, Jean‐Luc; Zimmermann, H

doi:10.2807/esw.07.23.02237-en

Cited by 6 publications

(6 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Outbreaks were repeatedly reported from different Swiss regions but since 1986 not from the municipality of Grabs. Thus naturally occurring boosters, increasing the antibody levels, are not very likely (Paget et al, 2000;Richard and Zimmermann, 2003).…”

Section: Discussionmentioning

confidence: 98%

Vaccinated students with negative enzyme immunoassay results show positive measles virus-specific antibody levels by immunofluorescence and plaque neutralisation tests

Tischer

Gassner²,

Richard

et al. 2007

Journal of Clinical Virology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 98%

Vaccinated students with negative enzyme immunoassay results show positive measles virus-specific antibody levels by immunofluorescence and plaque neutralisation tests

Tischer

Gassner²,

Richard

et al. 2007

Journal of Clinical Virology

View full text Add to dashboard Cite

“…Nevertheless, because of its limited coverage SSSN detected the beginning of outbreaks later in comparison to MNS (or not at all). Moreover, and although the reporting delay was shortened in the MNS during the 2003 epidemic as a result of the FOPH communication efforts [9,29], it was usually too long to plan effective interventions.…”

Section: Discussionmentioning

confidence: 99%

A 5-year comparison of performance of sentinel and mandatory notification surveillance systems for measles in Switzerland

2007

View full text Add to dashboard Cite

A sensitive, specific and timely surveillance is necessary to monitor progress towards measles elimination. We evaluated the performance of sentinel and mandatory-based surveillance systems for measles in Switzerland during a 5-year period by comparing 145 sentinel and 740 mandatory notified cases. The higher proportion of physicians who reported at least one case per year in the sentinel system suggests underreporting in the recently introduced mandatory surveillance for measles. Accordingly, the latter reported 2-36-fold lower estimates for incidence rates than the sentinel surveillance. However, these estimates were only 0.6-12-fold lower when we considered confirmed cases alone, which indicates a higher specificity of the mandatory surveillance system. In contrast, the sentinel network, which covers 3.5% of all outpatient consultations, detected only weakly and late a major national measles epidemic in 2003 and completely missed 2 of 10 cantonal outbreaks. Despite its better timeliness and greater sensitivity in case detection, the sentinel system, in the current situation of low incidence, is insufficient to perform measles control and to monitor progress towards elimination.

show abstract

“…The MMR‐vaccine coverage found in this study was relatively low for mumps and rubella. Recent outbreaks of MMR in Switzerland are a consequence of the insufficient and patchy vaccination coverage, observed despite the implementation of routine immunization with one dose in 1976 and with two doses in 1996 (26–28).…”

Section: Discussionmentioning

confidence: 99%

Influence of MMR‐vaccinations and diseases on atopic sensitization and allergic symptoms in Swiss schoolchildren

Roost

Gassner²,

Grize

et al. 2004

Pediatric Allergy Immunology

View full text Add to dashboard Cite

The prevalence of asthma and allergic disease has increased in many countries. It has been proposed that vaccinations may contribute to the development of allergic disease by reducing clinical infections in infancy or through the direct IgE-inducing effects of the vaccines. Evidence for a potential role of immunizations in the development of allergic disease is scarce. Therefore the objective was to study the associations between vaccinations against measles, mumps and rubella (MMR), natural infections of these diseases and atopic sensitization to indoor and outdoor allergens and allergic symptoms in schoolchildren. The cross-sectional study including 1537 8(th) grade school children aged 13-15 years living in 10 communities across Switzerland was organized in the framework of an environmental health surveillance program within the School Health Services (Swiss Surveillance Program of Childhood Asthma and Allergies with respect to Air Pollution and Climate, SCARPOL). Main outcome measures were asthma and sneezing during pollen season assessed by parental questionnaires and atopic sensitization determined by IgE concentrations to various allergens. It was found that parents' reported history of measles or mumps was associated with a stronger immune response than two or more vaccinations against the respective infection (measles: geometric mean IgG titers (GMT) lU/ml (95% Cl) 2.8 (2.0-3.9) vs. 1.2 (1.0-1.4), mumps: GMT PE/ml (95% Cl) 16.3 (13.9-19.1) vs. 8.5 (6.1-11.7). With respect to atopic sensitization similar associations for exposure by natural MMR-infections or MMR-vaccinations were found: measles: OR (95% Cl) 1.02 (0.53-1.96) vs. 1.22 (0.69-2.16), mumps: 0.59 (0.38-0.93) vs. 0.79 (0.49-1.27), rubella: 0.93 (0.61-1.43) vs. 0.95 (0.66-1.37), respectively. Inverse relationships were found between the risk of asthma and a positive disease history or vaccination of measles 0.36 (0.14-0.91) vs. 0.45 (0.21-0.98) or a positive serum titer against measles 0.65 (0.35-1.20). From the present study can be concluded that exposure by MMR-vaccinations or natural MMR-infections in childhood does not increase the risk of sensitization to common allergens as well as to allergic respiratory diseases. MMR-vaccinations or natural MMR-infections are therefore an unlikely factor contributing to the increase in atopic disease in developed countries.

show abstract

Recent increase in measles in children and teenagers in Switzerland

Abstract: A total of 387 clinical measles cases have been notified to the Swiss Federal Office of Public Health (SFOPH) in the last two months, a large increase compared to recent years.

Cited by 6 publications

References 0 publications

Vaccinated students with negative enzyme immunoassay results show positive measles virus-specific antibody levels by immunofluorescence and plaque neutralisation tests

Vaccinated students with negative enzyme immunoassay results show positive measles virus-specific antibody levels by immunofluorescence and plaque neutralisation tests

A 5-year comparison of performance of sentinel and mandatory notification surveillance systems for measles in Switzerland

Influence of MMR‐vaccinations and diseases on atopic sensitization and allergic symptoms in Swiss schoolchildren

Contact Info

Product

Resources

About