Recent Changes in the Spatial Pattern of Prostate Cancer in the U.S.

UV, latitude, and spatial trends in prostate cancer mortality: All sunlight is not the same (United States)

“…During the time periods covered by our analyses, the Northeast and Midwest regions (''Rust Belt'') experienced substantial population losses to the South and West (''Sun Belt'') [42]. Assuming that the major protective effects of UV exposure occur sometime prior to migration (as indicated by the NHANES analysis by John et al [43], below), the effect of these migrations would be to dilute the observed correlations between prostate cancer mortality and UV exposure Rogerson et al [44] reported a higher than expected increase in prostate cancer mortality in south-central states from 1990 to 1998, a finding that might be influenced by Sun Belt migration. However, a recent geographical study indicates that the protective effect of sunlight on prostate cancer mortality persists even after controlling for migration [45].…”

Race-specific geography of prostate cancer incidence

“…Genetic susceptibility, as well as age, dietary practices, physical activity, agrochemical exposures, infectious diseases, and socioeconomic status (SES) have been suggested as risk factors for disease[2] and/or disease detection [3-6]. …”

Prostate cancer mortality and birth or adult residence in the southern United States

“…Reports document birth in the southern region of the US predicts mortality from cardiovascular disease, stroke, dementia, and Alzheimer disease independently of residence in the South in adulthood, among both blacks and whites [9][10][11]. Although several studies have assessed the influence of adult residence on prostate cancer mortality [12][13][14][15][16], few studies have investigated the possible influence of place of birth on prostate cancer mortality within the US [3,17].…”