Recent advances in biopolymeric composite materials: Future sustainability of bone-implant

Oladapo, Bankole I.; Zahedi, S. Abolfazl; Ismail, Sikiru Oluwarotimi; Olawade, David B.

doi:10.1016/j.rser.2021.111505

Cited by 53 publications

(23 citation statements)

References 151 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Hence, the applications of BTE focus on the restoration of the native bone’s functionality by augmenting its regeneration rate with the aid of cells, osteogenic factors, or biomaterials. The perfect solution in improving bone recovery is represented by developing a biomaterial with good biological activity and mechanical properties that can maintain tissue functions [ 2 , 3 ].…”

Section: Introductionmentioning

confidence: 99%

Novel Trends into the Development of Natural Hydroxyapatite-Based Polymeric Composites for Bone Tissue Engineering

et al. 2022

View full text Add to dashboard Cite

In recent years, the number of people needing bone replacements for the treatment of defects caused by chronic diseases or accidents has continuously increased. To solve these problems, tissue engineering has gained significant attention in the biomedical field, by focusing on the development of suitable materials that improve osseointegration and biologic activity. In this direction, the development of an ideal material that provides good osseointegration, increased antimicrobial activity and preserves good mechanical properties has been the main challenge. Currently, bone tissue engineering focuses on the development of materials with tailorable properties, by combining polymers and ceramics to meet the necessary complex requirements. This study presents the main polymers applied in tissue engineering, considering their advantages and drawbacks. Considering the potential disadvantages of polymers, improving the applicability of the material and the combination with a ceramic material is the optimum pathway to increase the mechanical stability and mineralization process. Thus, ceramic materials obtained from natural sources (e.g., hydroxyapatite) are preferred to improve bioactivity, due to their similarity to the native hydroxyapatite found in the composition of human bone.

show abstract

Section: Introductionmentioning

confidence: 99%

Novel Trends into the Development of Natural Hydroxyapatite-Based Polymeric Composites for Bone Tissue Engineering

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Biomechanical properties, such as shear stress, deformation, and tensile or compressive stress, must match with natural healthy tissue or bone structure properties. Ideal scaffolds are produced with a well-regulated pore structure and can reproduce the shape of the implants [6][7][8][9]. Research studies have indicated that anisotropic porous structures with a combination of small and large pores in various shapes are advantageous for cell growth and can improve cell proliferation over time [7,10,11].…”

Section: Introductionmentioning

confidence: 99%

Mechanical Behaviour Evaluation of Porous Scaffold for Tissue-Engineering Applications Using Finite Element Analysis

et al. 2022

View full text Add to dashboard Cite

In recent years, finite element analysis (FEA) models of different porous scaffold shapes consisting of various materials have been developed to predict the mechanical behaviour of the scaffolds and to address the initial goals of 3D printing. Although mechanical properties of polymeric porous scaffolds are determined through FEA, studies on the polymer nanocomposite porous scaffolds are limited. In this paper, FEA with the integration of material designer and representative volume elements (RVE) was carried out on a 3D scaffold model to determine the mechanical properties of boron nitride nanotubes (BNNTs)-reinforced gelatin (G) and alginate (A) hydrogel. The maximum stress regions were predicted by FEA stress distribution. Furthermore, the analysed material model and the boundary conditions showed minor deviation (4%) compared to experimental results. It was noted that the stress regions are detected at the zone close to the pore areas. These results indicated that the model used in this work could be beneficial in FEA studies on 3D-printed porous structures for tissue engineering applications.

show abstract

“…Improving the bioactivity of PEEK composites for implants while maintaining their mechanical bioactive qualities has been a difficult task in recent years. 21 Tantalum and its complexes are biocompatible and wear resistant, making them excellent filler particles. [22][23][24][25] The capacity of borated tantalum (TaB 2 ) to increase tribological characteristics and enhance wound healing in bone tissue has been demonstrated.…”

Section: Introductionmentioning

confidence: 99%

“…The mechanical properties of PEEK were adversely affected by these bioactive chemicals. Improving the bioactivity of PEEK composites for implants while maintaining their mechanical bioactive qualities has been a difficult task in recent years 21 . Tantalum and its complexes are biocompatible and wear resistant, making them excellent filler particles 22–25 .…”

Section: Introductionmentioning

confidence: 99%

Evaluation of tribological and biological properties of TaB₂/PEEK composite coatings prepared by electrodeposition

Huang

Cao

et al. 2022

J of Applied Polymer Sci

View full text Add to dashboard Cite

It is well-known that a lower wear rate, favorable mechanical properties, and limited inflammatory response are critical factors in determining the long-term service of orthopedic implants. In this study, we prepare TaB 2 /PEEK coatings by electrophoretic deposition (EPD) of borated tantalum (TaB 2 ) and polyether-etherketone (PEEK) particles on a pure titanium plate (TA2). Nanoindenter, reciprocating ball-on-disc tester, and in vitro biological experiments were used to investigate the effects of TaB 2 particles on the mechanical properties, tribological properties, and biological properties of composite coatings. The results demonstrate that a small amount of TaB 2 particles were equally dispersed in the PEEK matrix, and the mechanical properties are improved, resulting in better tribological properties of the coating. In particular, the wear rate of P-TB-3 coating in the simulated body fluid (SBF) was 72% lower than that of the PEEK coating, with a friction coefficient (COF) of 0.164 and a wear rate of 1.45 Â 10 À6 mm 3 ÁN À1 m À1 , respectively. Furthermore, the P-TB-3 surface boosted Raw264.7 macrophage adherence and proliferation, with a potential to promote Raw264.7 macrophage transition to the M2 phenotype. These results suggest that the P-TB-3 coating prepared by EPD is considered as a promising implant replacement material.

show abstract

Recent advances in biopolymeric composite materials: Future sustainability of bone-implant

Cited by 53 publications

References 151 publications

Novel Trends into the Development of Natural Hydroxyapatite-Based Polymeric Composites for Bone Tissue Engineering

Novel Trends into the Development of Natural Hydroxyapatite-Based Polymeric Composites for Bone Tissue Engineering

Mechanical Behaviour Evaluation of Porous Scaffold for Tissue-Engineering Applications Using Finite Element Analysis

Evaluation of tribological and biological properties of TaB₂/PEEK composite coatings prepared by electrodeposition

Contact Info

Product

Resources

About

Recent advances in biopolymeric composite materials: Future sustainability of bone-implant

Cited by 53 publications

References 151 publications

Novel Trends into the Development of Natural Hydroxyapatite-Based Polymeric Composites for Bone Tissue Engineering

Novel Trends into the Development of Natural Hydroxyapatite-Based Polymeric Composites for Bone Tissue Engineering

Mechanical Behaviour Evaluation of Porous Scaffold for Tissue-Engineering Applications Using Finite Element Analysis

Evaluation of tribological and biological properties of TaB2/PEEK composite coatings prepared by electrodeposition

Contact Info

Product

Resources

About

Evaluation of tribological and biological properties of TaB₂/PEEK composite coatings prepared by electrodeposition