Reassessing the presence of Candida albicans in denture-related stomatitis

Effect of sodium bicarbonate on Candida albicans adherence to thermally activated acrylic resin

“…[9][10][11][12] However, simple attitudes such as the removal of the denture during the night and its correct hygiene with the daily usage of disinfecting solutions are mentioned in the literature as effective in the prevention and treatment of denture stomatitis. 4,[13][14][15] Thus, many studies have been performed with the objective of evaluating the efficiency of different disinfecting solutions in the control of Candida genus yeasts, searching for a disinfecting solution that would present excellent antimicrobial activity without harming the patient's health or causing alterations in the physical-structural characteristics of dentures. [16][17][18][19][20] Within this context, the objective of the present study was to evaluate the effect of sodium bicarbonate in the adherence of Candida albicans to thermally activated acrylic resin, comparing it to other disinfecting solutions already mentioned and tested in the literature.…”

“…1,2 This phenomenon, in association with factors such as trauma, diet, poor hygiene or predisposing systemic conditions (xerostomia, hormonal alterations and immunodepression caused by diabetes mellitus or HIV infection), may lead complete denture users to develop a condition known as denture stomatitis. [3][4][5][6][7] This condition is clinically characterized by a discrete focal inflammation on the palatum, which can evolve to an intense erythema in all area covered by the denture and, in some cases, to papillary hyperplasia. 6 According to Daniluk et al 5 (2006), Candida genus yeasts can be isolated from the human oral cavity in 64.9% of patients with denture stomatitis, being Candida albicans the most prevalent species (78.4%).…”

Relationship among local and functional factors in the development of denture stomatitis in denture wearers in northern Brazil

“…Dağistan et al 6 described DS as an inflammatory process that primarily involves the palatal mucosa (PM) when it is fully or partially covered by dentures, affecting 60-100% of acrylic denture users. Barbeau et al 7 noted that the etiology of DS is multifactorial and includes advanced age, decline in the defense mechanisms of the immune system, systemic diseases, smoking, the use of dentures while sleeping, poor oral hygiene resulting in the accumulation of plaque on the denture, poorly fitting dentures, and functional factors related to the occlusion. Pattanaik et al 1 reported that DS may be triggered by an allergy to residual resin monomers and is always associated with yeast from the genus Candida, particularly Candida albicans, which is a dimorphic fungus that has two major forms: a yeast form (commensal) and a hyphal form (pathogenic).…”

Detecção da expressão dos genes HWP1, ALS1 e ALS3 de C.albicans, por meio de RT-PCR em tempo real, após desinfecção química e por microonda, de resina acrílica para confecção de dentaduras

“…Em 1936, esta patologia foi relacionada à infecção por Candida sp. (BARBEAU et al, 2003) e esta relação tem se confirmado em vários outros trabalhos (BUDTZ-JORGENSEN, 1970; CEBALLOS; GONZALEZ-MOLES; URQUIA, 1990;FOTOS;HELLSTEIN, 1992;OLSEN, 1974).…”

“…Embora estudos correntes indiquem que a EP esteja geralmente associada com a presença do fungo C. albicans na saliva, na mucosa bucal e/ou na superfície interna da prótese removível WALKER, 1987;BARBEAU et al, 2003;CAMPOS et al, 2008;CUMMING et al, 1990;DAR-ODEH;SHEHABI, 2003;EMAMI et al, 2007;FARAH;ASHMAN;CHALLACOMBE, 2000;FIGUEIRAL et al, 2007;IACOPINO;WATHEN, 1992;KULAK;ARIKAN;KAZAZOGLU, 1997;PIRES et al, 2002;RAMAGE et al, 2004;WEBB et al, 1998;WILSON, 1998;ZISSIS;YANNIKAKIS;HARRISON, 2006), outros fatores também podem predispor seu desenvolvimento como os relacionados ao uso da prótese, à microbiota e às condições sistêmicas do hospedeiro.…”