The aim of this study was to isolate and identify Candida species from the oral cavity of denture wearers with denture-related stomatitis who were attended at the University Federal of Pará (Belém City, Pará State, Brazil). A total of 36 denture wearers with denture-related stomatitis were included, and type I (50%), type II (33%) and type III (17%) stomatitis were observed. Candida spp. were isolated from 89% of the cases and included five different Candida species. C. albicans was the most frequently recovered species (78% of the cases), followed by C. famata and C. tropicalis. We observed a significant association between Candida species isolation and unsatisfactory denture condition (p = 0.0017). Our results demonstrated the highly frequency of Candida species isolation in denture wearers with denture-related stomatitis and showed the relationship between these species and poor denture maintenance.

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Introduction:The aim of this study was to investigate the effects of Rosmarinus offi cinalis essential oil on germ tube formation by Candida albicans isolated from denture wearers. Methods: Ten C. albicans isolates recovered from denture wearers were tested using 10% fetal bovine serum with or without 4% R. offi cinalis essential oil. Results: The essential oil from R. offi cinalis completely inhibited germ tube formation in the investigated C. albicans isolates. Conclusions: The results demonstrate that the essential oil of R. offi cinalis modulates C. albicans pathogenicity through its primary virulence factor (i.e., germ tube formation was suppressed).

ResumoObjetivo: O objetivo deste estudo foi avaliar a relação entre fatores funcionais e qualitativos no desenvolvimento da estomatite protética (EP) (de acordo com a classificação de Newton) em usuários de dentadura acrílica residentes no norte do Brasil. Material e método: Um total de 99 pacientes, que usavam dentadura superior de resina acrílica parcial ou total, foi incluído neste estudo. Os participantes preencheram um formulário de dados epidemiológicos, que incluiu gênero, idade, fatores locais (hábitos de higiene, retirar a dentadura ao dormir, uso de colutório, condição atual da dentadura, idade da dentadura) e fatores funcionais (dimensão vertical de repouso, dimensão vertical de oclusão, oclusão, retenção, estabilidade estática e dinâmica). Para detectar leveduras, amostras foram coletadas da superfície interna da dentadura e da mucosa palatal em contato com esta. Posteriormente, as amostras foram cultivadas em ágar Sabouraud dextrose, observando-se características macro e microscópicas. Resultado: No presente estudo, não foi encontrada relação significante entre gênero e início da doença. Baseada na classificação de Newton, 36,3% dos pacientes apresentaram EP e 89,0% foram colonizados por leveduras; destes indivíduos, 50% tiveram lesões tipo I, 33,3% tiveram lesões tipo II e 16,6% tiveram lesões tipo III. Todos os fatores locais e qualitativos, exceto o uso de colutório, foram clinicamente relevantes para o desenvolvimento da doença. Conclusão: Estomatite protética em usuários de dentadura do norte do Brasil foi multifatorial, associando fatores locais, funcionais e microbiológicos.Descritores: Dentaduras; estomatite; higiene bucal; Candida. AbstractObjective: The aim of this study was to evaluate the relationship among functional and qualitative factors in the development of denture stomatitis (DS) (according to Newton's classification) in acrylic-based denture wearers residents from northern Brazil. Material and method: A total of 99 patients who wore partial or total acrylic resin-based upper dentures were included in this study. The subjects completed an epidemiological data form that includes the patient's gender, age, local factors (hygiene habits, remove denture to sleep, use of mouthwash, present condition of the denture, age of the denture) and functional factors (vertical dimension at rest, vertical dimension of occlusion, occlusion, retention, and static and dynamic stability). To detect yeasts, samples were collected from the inner surface of the dentures and from the palatal mucosa in contact with it. Subsequently, the samples were cultured on Sabouraud dextrose agar, observing macro and microscopic characteristics. Result: In the present study, we did not find any significant relationship between the gender and disease onset. Based on the Newton classification, 36.3% of the patients presented with DS and 89.0% were colonized by yeasts; of these subjects, 50% had type I lesions, 33.3% had type II lesions, and 16.6% had type III lesions. All of the qualitative and local factors, except th...

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O objetivo deste estudo foi isolar e identificar espécies de Candida da cavidade oral de usuários com estomatite relacionada à dentadura, atendidos na Universidade Federal do Pará (Cidade de Belém, Pará, Brasil). Foram incluídos 36 usuários de protese com estomatite relacionada à prótese, e foram observadas estomatite tipo I (50%), tipo II (33%) e tipo III (17%). Candida spp. foram isolados em 89% dos casos e incluíram cinco espécies diferentes de Candida. C. albicans, frequentemente recuperada (78% dos casos), seguida por C. famata e C. tropicalis. Observamos uma associação significativa entre o isolamento da espécie Candidas e a condição insatisfatória da prótese (p = 0,0017). Nossos resultados demonstraram a alta frequência de isolamento de espécies de Candida em usuários de próteses com estomatite relacionada à prótese e mostraram a relação entre essas espécies e má manutenção da prótese.

Obstructive sleep apnea (OSA) is a sleep-related respiratory condition that causes episodes of reduced breathing or complete stops, in addition to triggering other major health complications such as cardiovascular problems, stroke, fatigue and drowsiness. Usual treatments are performed with continuous positive airway pressure (CPAP) devices and mandibular advancement devices (MADs). The study presents a case report of a male patient, 57 years old, 84kg diagnosed with OSA, in which treatment with MADs made and adjusted in the patient is presented, so that beneficial results could be collected and confirmed. Observing that after 1 month of treatment with MADs there was an improvement in the percentage of sleep, as well as a reduction in AHI, in addition to greater oxygenation, absence of nucturia and reduction of snoring for some sporadic moments.

The effect of Rosmarinus officinalis essential oil on germ tube formation in Candida dubliniensis recovered from denture users O efeito do óleo essencial de Rosmarinus officinalis sobre a formação do tubo germinativo em Candida dubliniensis isolada de usuários de dentadura El efecto del aceite esencial de Rosmarinus officinalis sobre la formación del tubo germinativo en Candida dubliniensis aislada de usuarios de dentadura