Sandblasting, a conventional technique which is used for paint or scale removing, deburring, and glass decorating, has recently been developed into a powder blasting technique for brittle materials capable of producing micro-structures larger than 100 lm. This article describes an investigation of the effects of the impact angle of particles, the scanning times, and the standoff distance on the surface roughness, the weight-loss rate of samples with no mask, and the wall profile and overetching of samples with different mask patterns in powder blasting of soda-lime glass. The parameters are the various impact angles between 50 and 90°, the scanning times of a nozzle up to 40, and the standoff distances between 70 and 100 mm. The widths of the mask pattern are 0.2 mm, 0.5 mm, and 1 mm. The powder used is Al2O3 sharp particles, WA#600. The mass flow rate of powder during the erosion test is constant at 175 g/min and the blasting pressure of the powder is 0.2 Mpa. After a series of necessary experiments are performed, the results are investigated and analysed. As a result, a fundamental basis is established that can be applied to powder blasting to produce micro-mechanical parts of glass.