Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis

Javanbakht, Mohammad Hassan; Keshavarz, Seyed Ali; Djalali, Mahmoud; Siassi, Fereydoun; Eshraghian, Mohammad Reza; Firooz, Alireza; Hassan, Sk. Sarif; Ehsani, Amir Hooshang; Chamari, Maryam; Mirshafiey, Abbas

doi:10.3109/09546630903578566

Cited by 140 publications

(132 citation statements)

References 24 publications

Supporting

Mentioning

120

Contrasting

Unclassified

Order By: Relevance

“…Two studies [29,30] enrolled pediatric patients who had a history of AD, and both studies showed that eczema area and severity index (EASI) was decreased after calcidiol supplementation. Similar findings were shown by the others [9,22,27,28] but with using the SCORAD.…”

Section: Groupsupporting

confidence: 91%

“…This could be of particular value as it overcomes the compliance problem that is commonly faced while using phototherapy [24], and has a higher safety profile when the side effects of phototherapy [25], or even topical steroids [26] are considered. The use of oral calcidiol in the management of AD has been proven before to be successful [9,22,[27][28][29][30]. Two studies [29,30] enrolled pediatric patients who had a history of AD, and both studies showed that eczema area and severity index (EASI) was decreased after calcidiol supplementation.…”

Section: Groupmentioning

confidence: 99%

See 1 more Smart Citation

Estimation of Calcidiol Level in Serum of Atopic Dermatitis Patients before and after NB-UVB Phototherapy in Comparison to Oral Vitamin D Therapy

Youssef¹,

Dorgham²,

Hegazy³

et al. 2017

J Clin Exp Dermatol Res

View full text Add to dashboard Cite

show abstract

Section: Groupsupporting

confidence: 91%

Section: Groupmentioning

confidence: 99%

Estimation of Calcidiol Level in Serum of Atopic Dermatitis Patients before and after NB-UVB Phototherapy in Comparison to Oral Vitamin D Therapy

Youssef¹,

Dorgham²,

Hegazy³

et al. 2017

J Clin Exp Dermatol Res

View full text Add to dashboard Cite

show abstract

“…This was attributed to chronic OS in AD that may provoke distribution of vitamin E into the target tissue. In human patients with AD, receiving vitamin E, significant improvement of clinical parameters with decrease of serum IgE levels have been shown in placebo-controlled studies (Tsoureli-Nikita et al 2002;Javanbakht et al 2011).…”

Section: Introductionmentioning

confidence: 99%

Plasma and skin vitamin E concentrations in canine atopic dermatitis

Kapun¹,

Salobir

Levart

et al. 2013

Veterinary Quarterly

View full text Add to dashboard Cite

Background: Altered homeostasis of vitamin E has been demonstrated in human atopic dermatitis. Data on plasma and skin vitamin E concentrations in canine atopic dermatitis (CAD) are not available. Objective: To determine vitamin E concentrations in plasma and skin of atopic dogs. Animals and Methods: Vitamin E concentrations in plasma and full-thickness skin biopsies of 15 atopic dogs were related to CAD extent and severity index (CADESI-03) scores and compared to the equivalent concentrations in 17 healthy dogs. Statistically significant differences of measured parameters between the two groups were determined by the nonparametric Mann Whitney U test and correlations between CADESI-03 scores and vitamin E concentrations were evaluated by the Spearman rank test. A value of P < 0.05 was considered significant. Results: Plasma concentrations of vitamin E were significantly lower in atopic dogs than in healthy dogs, with median values of 29.8 and 52.9 mmol/L, respectively. Skin vitamin E values did not differ significantly between patients and healthy controls. The median concentration of skin vitamin E in atopic dogs was higher than that in healthy dogs. No significant correlations were found between CADESI-03 score and plasma vitamin E or skin vitamin E concentrations. Conclusions: Significantly lower plasma vitamin E concentrations in atopic dogs than in healthy controls indicate altered homeostasis of vitamin E in CAD. Clinical importance: Further investigation into vitamin E supplementation in CAD is warranted.

show abstract

“…12 Previous studies have shown that vitamin D can be given as a protective therapy to reduce the severity of AD. 10,19,20 The American Academy of Pediatrics (AAP) recommends giving 400 IU of vitamin D as a supplement to newborns to prevent vitamin D deficiency. 5 In conclusion, there is a moderate correlation between serum 25-hydroxyvitamin-D level and SCORAD index in children with atopic dermatitis.…”

Section: Resultsmentioning

confidence: 99%

Serum 25-hydroxyvitamin-D level and atopic dermatitis severity in children

Munawwarah¹,

Evalina²,

Sofyani³

2018

View full text Add to dashboard Cite

Background Vitamin D plays an important role in the immune system. It inhibits B-lymphocyte proliferation and modulates the humoral response to suppress IgE production. Studies on the relationship between serum 25-hydroxyvitamin-D level and the severity of atopic dermatitis in several countries have had varying results. Objective To assess for a possible correlation between serum 25-hydroxyvitamin-D level and atopic dermatitis severity in children. Methods A cross-sectional study was conducted in 26 children with atopic dermatitis from September to December 2015. We evaluated the severity of disease using the Scoring of Atopic Dermatitis

show abstract

Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis

Abstract: This study supports the contributing and beneficial effects of vitamins D and E in the treatment of atopic dermatitis.

Cited by 140 publications

References 24 publications

Estimation of Calcidiol Level in Serum of Atopic Dermatitis Patients before and after NB-UVB Phototherapy in Comparison to Oral Vitamin D Therapy

Estimation of Calcidiol Level in Serum of Atopic Dermatitis Patients before and after NB-UVB Phototherapy in Comparison to Oral Vitamin D Therapy

Plasma and skin vitamin E concentrations in canine atopic dermatitis

Serum 25-hydroxyvitamin-D level and atopic dermatitis severity in children

Contact Info

Product

Resources

About