Ramosetron for Preventing Postoperative Nausea and Vomiting in Women Undergoing Gynecological Surgery

Fujii, Yoshitaka; Saitoh, Yuhji; Tanaka, Hiroyoshi; Toyooka, Hidenori

doi:10.1097/00000539-200002000-00043

Cited by 32 publications

(31 citation statements)

References 5 publications

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“…[13] Fujii Y e al studied the effect of Ramosetron for preventing postoperative nausea and vomiting in women undergoing gynaecological surgery and also compared Ramosetron and Granisetron for preventing postoperative nausea and vomiting after gynaecologic surgery and concluded that prophylactic therapy with Ramosetron is more effective than Granisetron for the long term prevention of PONV after major gynaecologic surgery. [28] Mild headache, constipation and dizziness have been reported as side effects with all three drugs as was also seen in our study but no serious side effects were seen.…”

Section: Discussionsupporting

confidence: 84%

A Comparative Study of Intravenous Ondansetron, Granisetron and Ramosetron for Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Caesarean Section

R¹,

Umesh²,

Rohan³

2017

jemds

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BACKGROUNDNausea and vomiting after regional anaesthesia for caesarean delivery are common occurrences. Despite of high incidence of PONV in caesarean section, there are limited studies to compare antiemetic drugs. This study compares intravenous ondansetron, granisetron, ramosetron in patients undergoing LSCS with respect to efficacy in preventing PONV. Study Design-Prospective, observational study.

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Section: Discussionsupporting

confidence: 84%

A Comparative Study of Intravenous Ondansetron, Granisetron and Ramosetron for Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Caesarean Section

R¹,

Umesh²,

Rohan³

2017

jemds

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“…It has also been shown to be effective for PONV prophylaxis in a dose of 0.3 mg given at the end of surgery (IIIA). 48 COMPARISON BETWEEN THE DIFFERENT 5-HT 3 …”

mentioning

confidence: 99%

Evidence-based management of postoperative nausea and vomiting: a review

Habib

Gan

2004

Can J Anesth/J Can Anesth

196

106

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P Pu ur rp po os se e: : To provide evidence-based guidelines for the prophylaxis and treatment of postoperative nausea and vomiting (PONV).S So ou ur rc ce e: : Literature from randomized controlled trials, systematic reviews, logistic regression analyses and expert opinion in the management of PONV.P Pr ri in nc ci ip pa al l f fi in nd di in ng gs s: : The etiology of PONV is multifactorial. Patient, anesthesia, and surgery related risk factors have been identified. Universal PONV prophylaxis is not cost-effective. Identification of patients at high-risk of PONV allows targeting prophylaxis to those who will benefit most from it. No prophylaxis is needed for patients at low risk for PONV. For patients at moderate risk for PONV, prophylaxis using a single antiemetic or a combination of two agents should be considered. Double and triple antiemetic combinations should be considered for patients at high risk for PONV. Furthermore, a multimodal approach should be adopted incorporating steps to keep the baseline risk of PONV low. The optimum cost-effective approach to the management of PONV will differ between an ambulatory centre and an inpatient hospital setting. For the treatment of established PONV in patients who failed prophylaxis, patients should not receive a repeat dose of the prophylactic antiemetic. Rather, a drug acting at a different receptor should be used. Beyond six hours after surgery, patients can be treated with any of the agents used for prophylaxis, except dexamethasone and transdermal scopolamine.C Co on nc cl lu us si io on n: : PONV are common after anesthesia and surgery. We provided evidence-based guidelines for the management of this problem based on the available literature. Objectif : Énoncer des lignes de conduite fondées sur des données probantes pour la prévention et le traitement des nausées et des vomissements postopératoires (NVPO). Source : Les publications d'essais contrôlés et randomisés, les études méthodiques, les analyses de régression logistique et l'opinion d'experts sur le traitement des NVPO. Constatations principales : L'origine des NVPO est multifactorielle. Les facteurs de risque reliés au patient, à l'anesthésie et au type de chirurgie sont connus. La prévention universelle des NVPO n'est pas rentable. L'identification des patients à haut risque de NVPO permet

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“…In addition, the manufacturer's recommended dose is 0.3 mg IV once a day. [21], [22] Therefore, Ramosetron at the 0.3 mg dose was chosen for our study.…”

Section: Discussionmentioning

confidence: 99%

A Comparative Study of Granisetron, Ramosetron and Palonosetron as Antiemetics in Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Surgeries

Yatoo¹,

Mahotra²,

Mehta³

et al. 2016

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Ramosetron for Preventing Postoperative Nausea and Vomiting in Women Undergoing Gynecological Surgery

Abstract: This randomized, double-blinded, placebo-controlled trial in 120 women found the effective dose of ramosetron for preventing postoperative nausea and vomiting after gynecological surgery to be 0.3 mg.

Cited by 32 publications

References 5 publications

A Comparative Study of Intravenous Ondansetron, Granisetron and Ramosetron for Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Caesarean Section

A Comparative Study of Intravenous Ondansetron, Granisetron and Ramosetron for Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Caesarean Section

Evidence-based management of postoperative nausea and vomiting: a review

A Comparative Study of Granisetron, Ramosetron and Palonosetron as Antiemetics in Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Surgeries

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