Radiotherapy of Benign Diseases—Scleredema Adultorum Buschke

Abstract

. Regardless of the possible mechanisms in pathogenesis and treatment of scleredema adultorum Buschke, the application of ionizing radiation is an important, effective and well-tolerated therapy option in the treatment of severe cases and may candidate as the first-line treatment of this disease.

Results of Postoperative 90Sr Radiotherapy of Keloids in View of Patients’ Subjective Assessment

“…Other unfavorable factors which were identified in previous studies, like keloid length, familial disposition and etiology (e.g., inflammation, burn), could not be confirmed by our data. Postoperative radiotherapy reliably resulted in alleviation or elimination of symptoms in the majority of patients [18,21,28,29,36,41].…”

Biologically Effective Doses of Postoperative Radiotherapy in the Prevention of Keloids

“…Keloids are formed by intrinsically normal polyclonal fibroblasts that are responding to an abnormal extracellular signal [11]. Keloids belong to the class of hyperproliferative diseases, just as pterygium of the eye, Dupuytren's disease, scleredema adultorum Buschke and Peyronie's disease [27,37,47]. Surgery alone of keloids results in recurrences in 50-80% of cases [4,13,44].…”

Scleredema diabeticorum – A case report

“…The results were similar to those of Yuksek et al who reported a case of scleredema that improved markedly with low-dose broad-band UVA plus colchicine treatment (Yuksek et al, 2010). Konemann et al in 2004 described the case of a 58-yearold patient with scleredema of the neck and upper trunk who was treated twice within 6 months by electron-beam radiation therapy. The authors concluded that regardless of the possible mechanisms in pathogenesis and treatment of scleredema adultorum Buschke, the application of ionizing radiation is an important, effective and well-tolerated therapy option in the treatment of severe cases and may be considered as the first-line treatment of this disease (Konemann et al, 2004).…”