Radioprotective activity of neutral polysaccharides isolated from the fruiting bodies of Hohenbuehelia serotina

Li, Xiaoyü; Wang, Lu; Wang, Zhenyu

doi:10.1016/j.ejmp.2015.02.004

Cited by 21 publications

(8 citation statements)

References 37 publications

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“…However, the N doped TiO 2 -carbon composites exhibit a wider and stronger absorption of visible light around 500 nm. As reported in the literature, N and Ti 3+ doping can improve the TiO 2 valence band edge that induces visible light absorption as a result. Compared to the pure TiO 2 (P25), it is observed that TiO 2 -C-N and TiO 2 -C-A obviously have better light absorption in both the UV light and visible light regions, attributed to the N/Ti 3+ doping and the existence of oxygen vacancy.…”

Section: Resultsmentioning

confidence: 59%

Dual Functional N-Doped TiO₂-Carbon Composite Fibers for Efficient Removal of Water Pollutants

Zhang

et al. 2018

ACS Sustainable Chem. Eng.

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3D hierarchically structured porous carbon composite short fibers were prepared by carbonizing in N 2 and activating in CO 2 microcellulose fibers originally tethered with nano-TiO 2 . The TiO 2 nanoparticles grew in situ on the cellulose surface and inside-out the body of cellulose during their original hydrolysis synthesis process assisted by microwave irradiation, creating sufficient adsorption sites of hydroxyl groups and exposing abundant interfaces after heat treatment. The obtained carbonized fibers displayed rapid adsorption of methylene blue, phenol, and Cr (VI) and exhibited high adsorption capacity, outperforming commercial activated carbon powders having 50% more surface area. Moreover, the composite effectively photocatalyzed the oxidation of phenol and the reduction of Cr (VI) under both UV− vis and visible light. The enhanced photocatalytic activity was believed to be due to (1) the doping of N atoms to the TiO 2 crystal lattice resulting from the formation of Ti 3+ and oxygen vacancies during the carbonization process and (2) the interfaces formed between TiO 2 and the carbon, which promotes charge transfer and inhibit electron−hole recombination. The dualfunctional TiO 2 -carbon composite fibers made by this simple approach with many naturally endowed properties can also be repeatedly used after regeneration, opening up a sustainable opportunity for their versatile applications for both water and air decontamination.

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Section: Resultsmentioning

confidence: 59%

Dual Functional N-Doped TiO₂-Carbon Composite Fibers for Efficient Removal of Water Pollutants

Zhang

et al. 2018

ACS Sustainable Chem. Eng.

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“…Because ionizing radiation damages cells by creating an imbalance in their prooxidant to antioxidant ratio, it was of interest to find out if antioxidative polysaccharides might protect against radiation-induced adverse effects. This seems to be the case as illustrated by the following observations: (a) Joseph, et al [ 239 ] found that a polysaccharide-protein complex from Phellinus rimosus mushrooms administered intraperitoneally to mice exposed to γ-radiation resulted in enhanced levels of antioxidants in liver and brain tissues and in an increased survival of the animals; (b) A related study by Li, et al [ 240 ] found that a polysaccharide from Hohenbuehelia serotina mushrooms induced an increase in the quantity of bone marrow, reduced the rates of chromosome aberrations and micronuclei in bone marrow, and blocked the apoptotic pathway of splenocytes in mice exposed to γ-radiation; and (c) A β-glucan from the mushroom Ganoderma lucidum extended the survival of mice exposed to a lethal dose of γ-radiation after 30 days by 66% post-irradiation compared to 83% observed with the anti-radiation drug amifostine [ 241 ].…”

Section: Additional Health Benefitsmentioning

confidence: 99%

Mushroom Polysaccharides: Chemistry and Antiobesity, Antidiabetes, Anticancer, and Antibiotic Properties in Cells, Rodents, and Humans

Friedman

2016

Foods

265

150

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More than 2000 species of edible and/or medicinal mushrooms have been identified to date, many of which are widely consumed, stimulating much research on their health-promoting properties. These properties are associated with bioactive compounds produced by the mushrooms, including polysaccharides. Although β-glucans (homopolysaccharides) are believed to be the major bioactive polysaccharides of mushrooms, other types of mushroom polysaccharides (heteropolysaccharides) also possess biological properties. Here we survey the chemistry of such health-promoting polysaccharides and their reported antiobesity and antidiabetic properties as well as selected anticarcinogenic, antimicrobial, and antiviral effects that demonstrate their multiple health-promoting potential. The associated antioxidative, anti-inflammatory, and immunomodulating activities in fat cells, rodents, and humans are also discussed. The mechanisms of action involve the gut microbiota, meaning the polysaccharides act as prebiotics in the digestive system. Also covered here are the nutritional, functional food, clinical, and epidemiological studies designed to assess the health-promoting properties of polysaccharides, individually and as blended mixtures, against obesity, diabetes, cancer, and infectious diseases, and suggestions for further research. The collated information and suggested research needs might guide further studies needed for a better understanding of the health-promoting properties of mushroom polysaccharides and enhance their use to help prevent and treat human chronic diseases.

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“…In addition, NHSP can change the organ index. The neutral polysaccharides from Hohenbuehelia serotina can prevent apoptosis of splenocytes ( Li et al, 2015 ). The spleen can activate T-lymphocytes and B-lymphocytes and play an important role in the body’s immune response.…”

Section: Discussionmentioning

confidence: 99%

Neutral Polysaccharides From Hohenbuehelia serotina With Hypoglycemic Effects in a Type 2 Diabetic Mouse Model

Liu

Wang

et al. 2022

Front. Pharmacol.

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Neutral polysaccharides (NHSPs) from the mushroom Hohenbueheliaserotina were purified by D301/D152 resin ion-exchange chromatography and DEAE-cellulose anion exchange chromatography. The weight-average molecular weight (MW) and number-average molecular weight (Mn) of NHSP were 1,821 and 820.55 kDa, respectively. A monosaccharide component analysis showed that NHSP was composed of glucose, galactose, and mannose in molar ratio 2.6:2.1:1.0. FT-IR and NMR (1H and HSQC) spectroscopic analyses revealed that NHSP contained mainly 1,3-linked β-D-glucose, 1,4-linked β-D-glucose, 1,6-linked β-D-mannose, 1,6-linked α-D-mannose, and 1,6-linked β-D-galactose. The thermogravimetric analysis (TGA) showed that NHSP has good thermal stability below 250°C. NHSP notably reduced the blood glucose level (hypoglycemic effect) at dose 200 mg/kg for 21 days in a type 2 diabetic mouse model. NHSP reduced the liver index significantly, suggesting that it may help prevent hepatic steatosis or hepatomegaly.

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Radioprotective activity of neutral polysaccharides isolated from the fruiting bodies of Hohenbuehelia serotina

Cited by 21 publications

References 37 publications

Dual Functional N-Doped TiO₂-Carbon Composite Fibers for Efficient Removal of Water Pollutants

Dual Functional N-Doped TiO₂-Carbon Composite Fibers for Efficient Removal of Water Pollutants

Mushroom Polysaccharides: Chemistry and Antiobesity, Antidiabetes, Anticancer, and Antibiotic Properties in Cells, Rodents, and Humans

Neutral Polysaccharides From Hohenbuehelia serotina With Hypoglycemic Effects in a Type 2 Diabetic Mouse Model

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Radioprotective activity of neutral polysaccharides isolated from the fruiting bodies of Hohenbuehelia serotina

Cited by 21 publications

References 37 publications

Dual Functional N-Doped TiO2-Carbon Composite Fibers for Efficient Removal of Water Pollutants

Dual Functional N-Doped TiO2-Carbon Composite Fibers for Efficient Removal of Water Pollutants

Mushroom Polysaccharides: Chemistry and Antiobesity, Antidiabetes, Anticancer, and Antibiotic Properties in Cells, Rodents, and Humans

Neutral Polysaccharides From Hohenbuehelia serotina With Hypoglycemic Effects in a Type 2 Diabetic Mouse Model

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Product

Resources

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Dual Functional N-Doped TiO₂-Carbon Composite Fibers for Efficient Removal of Water Pollutants

Dual Functional N-Doped TiO₂-Carbon Composite Fibers for Efficient Removal of Water Pollutants