Radiographic presentation of pulmonary tuberculosis in severely immunosuppressed HIV-seropositive patients

Asimos, Andrew W; Ehrhardt, Jason

doi:10.1016/s0735-6757(96)90049-2

Cited by 17 publications

(9 citation statements)

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“…This lower frequency of cavitation has also been documented in other immunocompromised patients, such as HIV-positive subjects with associated TB [28]. One recent study revealed that cavitation was a predictor of smear positivity in patients with pulmonary TB [29].…”

Section: Discussionsupporting

confidence: 53%

The Impact of Age on the Demographic, Clinical, Radiographic Characteristics and Treatment Outcomes of Pulmonary Tuberculosis Patients in Taiwan

et al. 2008

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Section: Discussionsupporting

confidence: 53%

The Impact of Age on the Demographic, Clinical, Radiographic Characteristics and Treatment Outcomes of Pulmonary Tuberculosis Patients in Taiwan

et al. 2008

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“…It has also been shown that these atypical presentations occur more frequently in patients with advanced immunosuppression [7][8][9]. As a result and particularly due to lack of cavitations, HIV-infected patients have a reduced mycobacterial count.…”

Section: Discussionmentioning

confidence: 99%

“…In high TB prevalence areas such as Ethiopia, where M. tuberculosis infection frequently precedes HIV infection, a significant proportion of patients with active TB presents earlier in the course of HIV infection with upper lobe fibro-cavitary lesions typical of reactivation TB and intact tuberculin reactivity. This is in contrast to places where the prevalence of M. tuberculosis infection before HIV infection is low and atypical presentations of TB are more frequent [7][8][9][10]. Negative sputum smears for AFB occur more commonly in HIV-positive patients with advanced immunosuppression.…”

Section: Introductionmentioning

confidence: 94%

The Relationship between Disease Pattern and Disease Burden by Chest Radiography, M. tuberculosis Load, and HIV Status in Patients with Pulmonary Tuberculosis in Addis Ababa

et al. 2004

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CXR findings in the setting of an underlying HIV infection tend to be more atypical and could present as either normal or with minimal involvement. In general, HIV-positive patients had lower colony count of M. tuberculosis than HIV-negative patients. Of particular interest is the finding of a large number of normal chest X-rays in HIV-infected patients. With the rising incidence of both tuberculosis and HIV infection in Ethiopia, the finding of a normal chest X-ray and a negative smear poses a challenge for the diagnosis of pulmonary tuberculosis.

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“…Asimos с соавт. (1996) подчеркивается, что рентгенологические критерии диагностики туберкулеза легких у лиц без ВИЧ-инфекции не подходят для постановки диагноза у лиц с ВИЧ-инфекцией [5].…”

Section: вичunclassified

Criteria of Modern Tuberculosis Diagnostics in Hiv-Infection Patients

Пантелеев¹,

Nikulina²,

Dracheva³

et al. 2016

Med. sov.

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ВВЕДЕНИЕОбщепринятое представление о своевременном, или раннем, выявлении туберкулеза основано на малых сроках выявления процесса от начала его развития, характеристи-ках изменений в пораженном органе, диагностике форм туберкулезного процесса ограниченной распространенно-сти в легочной ткани, отсутствии деструктивных изменений. К таковым традиционно относят очаговый, ограниченный инфильтративный и диссеминированный туберкулез лег-ких, туберкулезный плеврит. С бактериологической точки зрения к своевременно выявленным формам туберкулеза причисляют случаи туберкулеза без бактериовыделения. Важным критерием своевременности выявления туберку-леза является диагностика этого заболевания на бессим-птомном этапе при выполнении профилактических осмо-тров или при клиническом минимуме обследования.В условиях разрастающейся эпидемии туберкулеза у пациентов с ВИЧ-инфекцией важной диагностической проблемой является вопрос не только о быстрой и точ-ной диагностике, но и о возможности раннего выявле-ния, опорных критериях своевременной диагностики этого заболевания, развивающегося в условиях иммуно-супрессии.В диагностике туберкулеза на поздних стадиях ВИЧ-инфекции существует несколько трудностей. С одной стороны, это нетипичность проявлений заболевания, часто затрудняющая быструю диагностику. С другой сто-роны, остропрогрессирующий характер туберкулеза, требующий быстрой постановки диагноза. При этом задержка в диагностике туберкулеза в начале лечения существенно повышает смертность больных с ВИЧ-инфекцией.По данным большинства авторов, туберкулез у боль-ных ВИЧ-инфекцией выявляется при обращении [1]. Так, С.Ю. Красноборова (2008) In the overwhelming majority of cases (81.7%) tuberculosis was diagnosed when the patient sought medical aid. It was established than 71.7% of patients underwent the chest X-ray in less than a year before tuberculosis diagnosis and a half of them -in less than 6 month, which allows speaking about the low informative value of the chest X-ray for HIV patients even with the interval two times per year. It was established that the most frequent form of early tuberculosis diagnostics is tuberculosis of intrathoracic lymphatic nodes that should be considered as a criteria of timeliness of tuberculosis identification in HIV persons.

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Radiographic presentation of pulmonary tuberculosis in severely immunosuppressed HIV-seropositive patients

Cited by 17 publications

References 10 publications

The Impact of Age on the Demographic, Clinical, Radiographic Characteristics and Treatment Outcomes of Pulmonary Tuberculosis Patients in Taiwan

The Impact of Age on the Demographic, Clinical, Radiographic Characteristics and Treatment Outcomes of Pulmonary Tuberculosis Patients in Taiwan

The Relationship between Disease Pattern and Disease Burden by Chest Radiography, M. tuberculosis Load, and HIV Status in Patients with Pulmonary Tuberculosis in Addis Ababa

Criteria of Modern Tuberculosis Diagnostics in Hiv-Infection Patients

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