Radio-guided sentinel lymph node identification by lymphoscintigraphy fused with an anatomical vector profile: clinical applications

Asabella, Artor Niccoli; Antonica, Filippo; Renna, Maria Antonia; Rubini, D.; Notaristefano, Antonio; Nicoletti, A; Rubini, Giuseppe

doi:10.1007/s12149-013-0758-9

Cited by 3 publications

(3 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The primary objective of this study was to determine its applicability using SLN imaging as an example rather than testing the clinical validity or the possible influence on therapeutic decisions. Several previous studies attempted to couple information about the SLN with anatomical information (3,5,18,24,28,32,34,37,38,40). The fh-SPECT system declipse ® SPECT used in the present study already allows such an approach, as it was originally developed for the intraoperative imaging of SLN, but not in combination with an ultrasound device.…”

Section: Discussionmentioning

confidence: 99%

“…In addition, SPECT/CT devices are expensive and not widely available (e. g. in our institution). Nicolli-Asabella et al used anatomical reference cards that were fused with lymphoscintigraphy images to enrich them with morphological information (24). A sonographic approach was followed by Sever et al who used periareolar intradermally injected ultrasound contrast agents (microbubbles) to image lymphatic drainage in breast cancer patients with ultrasound (28).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Real-time ultrasound and freehand-SPECT

Winkens¹,

Opfermann²,

Elsner³

et al. 2014

Nuklearmedizin

View full text Add to dashboard Cite

The fusion imaging concept combining SLN information with ultrasound images presented here proves to be feasible and technically successful. However, significant technical limitations were shown in fh-SPECT quality and fusion precision. Subject to technical optimisation of SPECT quality and co-registration, a meaningful contribution to the preoperative planning of lymph node therapy is imaginable. Thus, fundamentally a preoperative histological examination by fh-SPECT/US-guided biopsy is possible.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Real-time ultrasound and freehand-SPECT

Winkens¹,

Opfermann²,

Elsner³

et al. 2014

Nuklearmedizin

View full text Add to dashboard Cite

show abstract

“…Even though Adobe Photoshop is not specialist medical software, it is a professional image processing and graphics software package that assured the sizes of the two images were the same and that the images completely overlapped. Adobe Photoshop has been used in prior studies to fuse images to recognize the anatomical location of lesions, as well as to analyze cells and their immunologically marked intracellular constituents [ 21 , 22 ].…”

Section: Discussionmentioning

confidence: 99%

Visualization of Anatomic Variation of the Anterior Septal Vein on Susceptibility-Weighted Imaging

et al. 2016

View full text Add to dashboard Cite

Background and PurposeUnderstanding the anatomy of the anterior septal vein (ASV) is critical for minimally invasive procedures to the third ventricle and for assessing lesion size and venous drainage in the anterior cranial fossa. Accordingly, this study evaluated topographic anatomy and anatomic variation of the ASV using susceptibility-weighted imaging (SWI).MethodsSixty volunteers were examined using a 3.0T MR system. The diameter of the ASV and distance between bilateral septal points were measured. ASVs were divided into types 1 (only drains frontal lobe) and 2 (drains both frontal lobe and head of the caudate nucleus). We evaluated the ASV-internal cerebral vein (ICV) junction based on its positional relationship with the appearance of a venous angle or a false venous angle and the foramen of Monro. Fused SW and T1-weighted images were used to observe positional relationships between the course of the ASV and the surrounding brain structures.ResultsThe ASV and its small tributaries were clearly visualized in 120 hemispheres (100%). The average diameter of ASVs was 1.05±0.17 mm (range 0.9–1.6 mm). The average distance between bilateral septal points was 2.23±1.03 mm (range 1.3–6.6 mm). The ASV types 1 and 2 were in 77 (64.2%) and 43 (35.8%) hemispheres, respectively. In 83 (69.2%) hemispheres, the ASV-ICV junction was situated at the venous angle and the posterior margin of the foramen of Monro. In 37 (30.8%) hemispheres, the ASV-ICV junction was situated beyond the posterior margin of the foramen of Monro. The average distance between the posteriorly located ASV-ICV junction and the posterior margin of the foramen of Monro was 6.41±3.95 mm (range 2.4–15.9 mm).ConclusionUsing SWI, the topographic anatomy and anatomic variation of the ASV were clearly demonstrated. Preoperative assessment of anatomic variation of the ASV may be advantageous for minimally invasive neurosurgical procedures.

show abstract