Radiation effects in life sciences

Sadrozinski, H. F-W.

doi:10.1016/j.nima.2003.08.109

Cited by 7 publications

(1 citation statement)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nuclear power plant leaks, terrorist attacks with so-called dirty bombs: one can easily imagine dire scenarios where one would quickly need to ascertain the exposure of a large population to ionising radiation, whose effect can be quite complex [16][17][18]. Up to now, the extent of the ionizing radiation exposure to individuals can be estimated by biological dosimetry methods based on, e.g., chromosome aberrations, lymphocyte depletions or cytogenetic analysis.…”

Section: Introductionmentioning

confidence: 99%

Multidimensional statistical analysis of PTR-MS breath samples: A test study on irradiation detection

Fedrigo

Hoeschen

Oeh

2010

International Journal of Mass Spectrometry

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Multidimensional statistical analysis of PTR-MS breath samples: A test study on irradiation detection

Fedrigo

Hoeschen

Oeh

2010

International Journal of Mass Spectrometry

View full text Add to dashboard Cite

Raman spectroscopic study of calf thymus DNA: an effect of proton‐ and γ‐irradiation

Synytsya

Alexa

Boer³

et al. 2007

J Raman Spectroscopy

View full text Add to dashboard Cite

Raman spectroscopy was applied to analyse structural changes in calf thymus double-stranded deoxyribonucleic acid (dsDNA) after proton-and g-irradiation (0.5, 5 and 50 Gy). Characteristic Raman bands of phosphodiester linkages, nucleic bases and deoxyribose moieties were sensitive to irradiation. A significant damage of the macromolecules was observed only at the highest dose (50 Gy) of both types of radiations. Spectral changes confirmed a radiation-induced alteration of the native structure of dsDNA. Nucleic bases, especially pyrimidines, were the most sensitive to radiation, while some alterations in the sugar-phosphate backbone were also detected. The differences in the dose-dependent effects of proton vs g-irradiation on studied biomolecule are discussed.

show abstract

Raman spectroscopic study of serum albumins: an effect of proton‐ and γ‐irradiation

Synytsya

Alexa

Boer³

et al. 2007

J Raman Spectroscopy

View full text Add to dashboard Cite

Raman spectroscopy was applied to analyse structural changes in serum albumins (bovine serum albumin, BSA; human serum albumin, HSA) following proton and g-irradiation (0.5, 5 and 50 Gy). Characteristic Raman bands of both polypeptide backbone and amino acid residues were sensitive to irradiation. Significant damage of HSA/BSA was observed only at the highest dose (50 Gy). Raman spectra confirmed radiation-induced denaturation, destruction of helical structures and aggregation of serum albumins. The differences in the dose-dependent effects of proton and g-radiation on studied proteins are discussed.

show abstract

Radiation effects in life sciences

Cited by 7 publications

References 20 publications

Multidimensional statistical analysis of PTR-MS breath samples: A test study on irradiation detection

Multidimensional statistical analysis of PTR-MS breath samples: A test study on irradiation detection

Raman spectroscopic study of calf thymus DNA: an effect of proton‐ and γ‐irradiation

Raman spectroscopic study of serum albumins: an effect of proton‐ and γ‐irradiation

Contact Info

Product

Resources

About