Racial and Ethnic Differences in the Management of Atrial Fibrillation

Tamirisa, Kamala P.; Al‐Khatib, Sana M.; Mohanty, Sanghamitra; Han, Janet K.; Gupta, Dhiraj; Russo, Andrea M.; Al‐Ahmad, Amin; Gillis, Anne M.; Thomas, Kevin L.

doi:10.1016/j.cjco.2021.09.004

Cited by 21 publications

(18 citation statements)

References 106 publications

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“…Despite non-Hispanic Black individuals being at lower risk for development of AF, Black patients are burdened more with palpitations, dyspnea on exertion, exercise intolerance, dizziness, dyspnea at rest, and chest discomfort compared with White or Hispanic patients. 106,107…”

Section: Strokementioning

confidence: 99%

State of the Science: The Relevance of Symptoms in Cardiovascular Disease and Research: A Scientific Statement From the American Heart Association

Jurgens¹,

Lee²,

Aycock³

et al. 2022

Circulation

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Symptoms of cardiovascular disease drive health care use and are a major contributor to quality of life. Symptoms are of fundamental significance not only to the diagnosis of cardiovascular disease and appraisal of response to medical therapy but also directly to patients’ daily lives. The primary purpose of this scientific statement is to present the state of the science and relevance of symptoms associated with cardiovascular disease. Symptoms as patient-reported outcomes are reviewed in terms of the genesis, manifestation, and similarities or differences between diagnoses. Specifically, symptoms associated with acute coronary syndrome, heart failure, valvular disorders, stroke, rhythm disorders, and peripheral vascular disease are reviewed. Secondary aims include (1) describing symptom measurement methods in research and application in clinical practice and (2) describing the importance of cardiovascular disease symptoms in terms of clinical events and other patient-reported outcomes as applicable.

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Section: Strokementioning

confidence: 99%

State of the Science: The Relevance of Symptoms in Cardiovascular Disease and Research: A Scientific Statement From the American Heart Association

Jurgens¹,

Lee²,

Aycock³

et al. 2022

Circulation

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“…The QRS wave rhythm was absolutely irregular, showing uneven RR intervals and a normal QRS wave pattern. The diagnosis of paroxysmal atrial fibrillation was in accordance with the diagnostic criteria developed by the 2018 Chinese Medical Association Electrophysiology and Pacing Section, “Atrial fibrillation: current understanding and treatment recommendations – 2018” [ 2 ].…”

Section: Methodsmentioning

confidence: 99%

“…It has been estimated that 6–12 million people worldwide will have AF in the US by 2050 and 17.9 million people in Europe by 2060 [ 1 ]. Current epidemiological studies indicate that AF is more prevalent in White patients than in other racial and ethnic groups [ 2 ]. In the Multi-Ethnic Study of Atherosclerosis (MESA), after adjusting for age and sex, non-Hispanic blacks, Hispanics, and Chinese Americans had 49%, 46%, and 65% lower rates of AF, respectively, compared with non-Hispanic White patients.…”

Section: Introductionmentioning

confidence: 99%

Predictive Value of Red Blood Cell Distribution Width and Atrial Diameter in Paroxysmal Atrial Fibrillation: A Cross-Sectional Study

Lin

Dai

et al. 2022

Med Sci Monit

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Background Atrial fibrillation (AF) is the most common arrhythmia and is associated with deleterious consequences. In addition to worsening a patient’s quality of life, AF is associated with stroke, heart failure, and increased mortality. Red blood cell distribution width (RDW) has been associated with an increased risk of death and adverse cardiovascular outcomes, while left atrial enlargement has been linked to atrial fibrillation (AF). However, the relationship among RDW, atrial diameter (AD), and paroxysmal AF is uncertain. The aim of this study was to investigate the relationship among RDW, atrial diameter, and paroxysmal AF. Material/Methods A total of 22 patients with paroxysmal AF and 100 patients with non-AF were included in the study. The demographic variables and baseline clinical characteristics of both groups were analyzed. Results The demographics and comorbidities were comparable between the paroxysmal AF and control groups, except for BMI (body mass index). RDW, high-sensitivity C-reactive protein (hs-CRP) levels, NT-pro-BNP levels, MPV/PLT (mean platelet volume/total platelet count), LAD, RAD, and CHA2DS2-VASc score were higher in the paroxysmal AF group versus the control group ( P <0.05). Binary logistic regression analyses demonstrated that RDW (OR: 2.557, 95% CI: 1.481~4.414), Hs-CRP (OR: 1.445, 95% CI: 1.144~1.825), MPV/PLT (OR: 1.342, 95% CI: 1.047~1.720), LAD (OR: 1.068, 95% CI: 1.007~1.132), and CHA 2 DS 2 -VASc score (OR: 1.645, 95% CI: 1.042~2.597) were independent predictors for paroxysmal AF ( P <0.05, respectively). The ROC analysis showed that the area under the curve for LAD was 0.692, the area under the curve for RAD was 0.566, the area under the curve for RDW was 0.811, and the area under the curve for MPV/PLT was 0.671. Conclusions LAD, RDW, and MPV/PLT were associated with paroxysmal AF.

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“…Whites are at higher risk for AF despite a higher prevalence of known risk factors for AF documented among other racial and ethnic groups. 45 The lifetime risk of AF increases markedly after age 50 years in European men and after age 60 years in women. 46 A similar age-dependent difference in AF risk has also been reported in Black men compared to Black women.…”

Section: Afmentioning

confidence: 99%