2022
DOI: 10.1161/cir.0000000000001089
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State of the Science: The Relevance of Symptoms in Cardiovascular Disease and Research: A Scientific Statement From the American Heart Association

Abstract: Symptoms of cardiovascular disease drive health care use and are a major contributor to quality of life. Symptoms are of fundamental significance not only to the diagnosis of cardiovascular disease and appraisal of response to medical therapy but also directly to patients’ daily lives. The primary purpose of this scientific statement is to present the state of the science and relevance of symptoms associated with cardiovascular disease. Symptoms as patient-reported outcomes are reviewed in terms of the genesis… Show more

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Cited by 37 publications
(25 citation statements)
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“…A key finding in this study was that patients hospitalised for HF experienced a high burden of symptoms, particularly depression. Additionally, consistent with previous studies carried out among hospitalised patients, breathlessness and fatigue were the symptoms with the highest prevalence and severity [ 16 , 17 , 18 ]. Mental health problems, pain, and decreased well-being had high percentages and were much more prevalent than symptoms considered to be typical, such as oedema and breathlessness.…”
Section: Discussionsupporting
confidence: 90%
“…A key finding in this study was that patients hospitalised for HF experienced a high burden of symptoms, particularly depression. Additionally, consistent with previous studies carried out among hospitalised patients, breathlessness and fatigue were the symptoms with the highest prevalence and severity [ 16 , 17 , 18 ]. Mental health problems, pain, and decreased well-being had high percentages and were much more prevalent than symptoms considered to be typical, such as oedema and breathlessness.…”
Section: Discussionsupporting
confidence: 90%
“…The ratio by E-SNT was critical (IR = 0.850), whereas the ratio by E-SM was unnecessary (IR = 0.563). In the second round, the four indicators rated as supplemental did not make a consensus among respondents (ranks 37,38,39,40). More than 60% considered monitor effects of stimulants as unnecessary (Table 6).…”
Section: Self-management: Cardiac Diseasementioning
confidence: 99%
“…The understanding natural course of cardiac disease may be hard for patients because of difficult pathology; however, knowing signs, symptoms, and disease process is helpful to adherent treatments and medication. 38 Among 45 self-management indicators, monitors effects of stimulants and Uses diary to monitor symptoms over time ranked the lowest, and they were rated as unnecessary by a few respondents in both rounds. They may have thought that these two indicators are redundant because there are some indicators for symptom and medication management.…”
Section: Indicatorsmentioning
confidence: 99%
“…Given that some acute stroke symptoms including fatigue, anxiety and dizziness may overlap with other cardiovascular and general medical conditions 38 it is important to identify patients who are experiencing stroke 'mimics', and to avoid unnecessary and expensive investigations and inappropriate long-term prevention treatments. Patients presenting with stroke symptoms may ultimately be diagnosed with other conditions such as migraine headache, vertigo, metabolic disturbances, brain tumours, or presyncope/syncope.…”
Section: Section 4: Emergency Department Evaluationmentioning
confidence: 99%