Quantitative determination of acrivastine and pseudoephedrine hydrochloride in pharmaceutical formulation by high performance liquid chromatography and derivative spectrophotometry

Quantification of antihistamine acrivastine in plasma by solid-phase extraction and high-performance liquid chromatography

“…These included derivative spectrophotometry [8], high-performance liquid chromatography with ultraviolet detection (HPLC-UV) [9], gas chromatography with mass spectrometric detection (GC-MS) [10,11], radioimmunoassay [12], and electrochemical measurement [13]. We have recently reported an HPLC-UV method to simultaneously analyze acrivastine and pseudoephedrine hydrochloride in Semprex ® -D capsules [14].…”

Comparison of HPLC and multivariate regression methods for hydrocortisone and lidocaine analysis of pharmaceutical preparations

“…LID can be determined by derivative spectrophotometry associated with fluorometholone in commercial products [11], by reverse-phase HPLC with its metabolites and other related compounds [12,13] and by means of capillary zone electrophoresis (CZE) with its metabolites in plasma [14].…”

Simultaneous analysis of the H1-antihistamine acrivastine and the decongestant pseudoephedrine hydrochloride by high-performance liquid chromatography

“…Methods used for acrivastine include gas chromatography-mass spectrometry [6] and radioimmunoassay [7], while methods used for pseudoephedrine hydrochloride are titrimetry [8], spectrophotometry [9] and high-performance liquid chromatography (HPLC) [8,10,11]. In the only study in which acrivastine and pseudoephedrine hydrochloride were simultaneously detected in a pharmaceutical formulation, HPLC and derivative spectrophotometry were used [12]. The HPLC method required a high flow rate of 3 mL/min, yet the retention time for acrivastine was still relatively long at approximately 6.5 min.…”