Quantitative Detection of Trace Level Cloxacillin in Food Samples Using Magnetic Molecularly Imprinted Polymer Extraction and Surface-Enhanced Raman Spectroscopy Nanopillars

Ashley, Jon; Wu, Kaiyu; Hansen, Mikkel Fougt; Schmidt, Michael; Boisen, Anja; Sun, Yi

doi:10.1021/acs.analchem.7b02725

Cited by 76 publications

(47 citation statements)

References 31 publications

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“…However, a weak signal corresponding to γ-Fe 3 O 4 particles were observed and it was almost negligible as compared to Fe 3 O 4 , because of the oxidation of Fe 3 O 4 during the coprecipitation and silanization. The results are almost same to those reported research[44,45].…”

supporting

confidence: 92%

Preparation of stoichiometric molecularly imprinted polymer coatings on magnetic particles for the selective extraction of auramine O from water

Yang

Muhammad

Yigaimu

et al. 2018

J of Separation Science

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A novel magnetic molecularly imprinted polymer for the selective recognition of auramine O was rationally designed via screening from a library of nonimprinted polymers. A stoichiometric ratio of functional monomer (itaconic acid) and template molecule (auramine O) was found to be 1.5. Meanwhile, the synthesized SiO @Fe O was modified by 0.5 mol/L hydrochloric acid to facilitate the preparation of magnetic molecularly imprinted polymer particles. Adsorption experiments showed that the magnetic polymer particles exhibited good selectivity, recoveries, and enrichment performance. The stoichiometric imprinted polymers have been employed for the selective preconcentration of auramine O from lake water sample. The high specificity of the stoichiometric imprinted polymers was proven in the extraction of mixture solution of auramine O, auramine O hydrochloride, and chrysoidine, and the recoveries ranged between 99.66 and 108.75% (RSD 2.6-3.7%, n = 3) for lake water. These results suggest that this method is effective and can be successfully applied to the analysis of auramine O in environmental water samples.

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supporting

confidence: 92%

Preparation of stoichiometric molecularly imprinted polymer coatings on magnetic particles for the selective extraction of auramine O from water

Yang

Muhammad

Yigaimu

et al. 2018

J of Separation Science

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“…For instance, Kamra et al presented a SERS‐MIP sensor for detection of nicotine . Ashley et al combined magnetic molecularly imprinted polymer with surface‐enhanced Raman spectroscopy detection for quantitative analysis of cloxacillin in pig serum . Although some studies on SERS‐MIPs have been carried out, there are few studies on SERS‐MIP sensors with metal‐nonmetal composites as the substrates.…”

Section: Introductionmentioning

confidence: 99%

Preparation of a high‐performance magnetic molecularly imprinted sensor for SERS detection of cyfluthrin in river

Wang

et al. 2019

J Raman Spectroscopy

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A novel magnetic molecularly imprinted sensor (Fe 3 O 4 /GO/Ag-MIPs) was successfully synthesized. Combining with the technique of surface-enhanced Raman scattering (SERS), it could be applied to detect cyfluthrin (LC). Herein, GO and Ag particles were anchored on the surface of the Fe 3 O 4 @SiO 2 to obtain the composite (Fe 3 O 4 /GO/Ag), which was prepared as a SERS substrate. Then, the Fe 3 O 4 /GO/Ag-MIPs (FGA-MIPs) prepared by precipitation polymerization was evaluated as the SERS imprinted sensor for selective detection of LC from aqueous medium. The morphology and structural properties of FGA-MIPs were characterized by a series of modern analysis measurements. The results proved that FGA-MIPs possessed wonderful magnetic separation, sensitive SERS detection, and selectivity. Under optimal conditions, it exhibited a good linear relationship (R 2 = 0.9926) between the Raman shift (at 1,004 cm −1 ) and the concentration of LC among 10 −3 -10 −8 mol/L, and the limit of detection was 10 −8 mol/L. Meanwhile, the selective experiment indicated that this material owned specific selectivity to the template molecules. Thus, the result of this experiment demonstrated that the FGA-MIPs was a highly sensitive and selective sensor material in the field of LC detection, and it provided a new approach to other residual pyrethroid detection in the environment water.

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“…In a different strategy, Ashley et al [183] combined the separation properties of magnetic molecularly imprinted polymer (MMIP)-based sample pretreatment with SERS detection for quantitative analysis of cloxacillin in pig serum. Magnetic FeO x nanospheres were synthesized and coated with mesoporous silica and metacryloxy propyl trimethoxyl silane to allow the polymerization of the MIP layer directly attached to the silica surface.…”

Section: Surface-enhanced Raman Spectroscopymentioning

confidence: 99%

Optical Biosensors for Label-Free Detection of Small Molecules

Peltomaa

Glahn-Martínez

Benito‐Peña

et al. 2018

Sensors

154

111

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Label-free optical biosensors are an intriguing option for the analyses of many analytes, as they offer several advantages such as high sensitivity, direct and real-time measurement in addition to multiplexing capabilities. However, development of label-free optical biosensors for small molecules can be challenging as most of them are not naturally chromogenic or fluorescent, and in some cases, the sensor response is related to the size of the analyte. To overcome some of the limitations associated with the analysis of biologically, pharmacologically, or environmentally relevant compounds of low molecular weight, recent advances in the field have improved the detection of these analytes using outstanding methodology, instrumentation, recognition elements, or immobilization strategies. In this review, we aim to introduce some of the latest developments in the field of label-free optical biosensors with the focus on applications with novel innovations to overcome the challenges related to small molecule detection. Optical label-free methods with different transduction schemes, including evanescent wave and optical fiber sensors, surface plasmon resonance, surface-enhanced Raman spectroscopy, and interferometry, using various biorecognition elements, such as antibodies, aptamers, enzymes, and bioinspired molecularly imprinted polymers, are reviewed.

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Quantitative Detection of Trace Level Cloxacillin in Food Samples Using Magnetic Molecularly Imprinted Polymer Extraction and Surface-Enhanced Raman Spectroscopy Nanopillars

Cited by 76 publications

References 31 publications

Preparation of stoichiometric molecularly imprinted polymer coatings on magnetic particles for the selective extraction of auramine O from water

Preparation of stoichiometric molecularly imprinted polymer coatings on magnetic particles for the selective extraction of auramine O from water

Preparation of a high‐performance magnetic molecularly imprinted sensor for SERS detection of cyfluthrin in river

Optical Biosensors for Label-Free Detection of Small Molecules

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