Quantitative assessment for stimulated saliva flow rate and buffering capacity in relation to different ages

Moritsuka, Michiyo; Kitasako, Yuichi; Burrow, Michael F.; Ikeda, Masaomi; Tagami, Junji; Nomura, Shintaro

doi:10.1016/j.jdent.2006.01.004

Cited by 65 publications

(48 citation statements)

References 24 publications

(30 reference statements)

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“…In our study, we found no correlation of salivary flow rate and buffering capacity at baseline. Also in our study, higher salivary flow rate before placement of appliances was significantly related to the higher buffer capacity at week 12 after the placement of appliances; this is in agreement with the conclusion of Moritsuka et al 27 CONCLUSION N The 6th to 12th week of orthodontic therapy is a period of the most intensive intraoral growth of S mutans and Lactobacillus spp and a time of very intensive salivary functions physiologic response.…”

Section: Discussionsupporting

confidence: 92%

“…Our findings are in agreement with the studies of Ulukapi et al, 18 who found a significant increase in salivary flow rate and no significant change in buffer capacity, which suggests that salivary flow rate is more sensitive to the placement of orthodontic appliances than buffer capacity. 17 Moritsuka et al 27 showed that higher salivary flow rate correlates with higher buffering capacity and that the quantitative saliva assessment is useful as a screening method to identify patients with a low buffering capacity. In our study, we found no correlation of salivary flow rate and buffering capacity at baseline.…”

Section: Discussionmentioning

confidence: 99%

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Salivary microbial and nonmicrobial parameters in children with fixed orthodontic appliances

Peroš

Meštrović

Anić-Milošević

et al. 2011

The Angle Orthodontist

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Objective: To determine the physiologic changes of salivary flow rate, pH, and buffer capacity and the levels of Streptococcus mutans and Lactobacillus spp in patients undergoing fixed orthodontic treatment. Materials and Methods: The study included 23 patients scheduled for fixed orthodontic therapy. All subjects received equal braces, bands, and brackets, bonded with the same material. Stimulated saliva samples were taken before placement of the appliance, and at weeks 6, 12, and 18 during the therapy. Salivary flow rate and salivary pH were measured, and the salivary buffer capacity was determined. Saliva samples were cultivated on selective microbial agar for microorganism detection. Results: A significant (P , .05) increase in stimulated salivary flow rate and salivary pH was found. The salivary levels of S mutans and Lactobacillus spp also inscreased significantly (P , .05), and the major peak was at week 12 of fixed orthodontic therapy. Conclusion: The 6th to 12th week of orthodontic therapy is the period of the most intensive intraoral growth of S mutans and Lactobacillus spp and a time of very intensive salivary functions and physiologic response. (Angle Orthod. 2011;81:901-906.)

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Salivary microbial and nonmicrobial parameters in children with fixed orthodontic appliances

Peroš

Meštrović

Anić-Milošević

et al. 2011

The Angle Orthodontist

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“…Olive oil has many properties helpful in ameliorating oral conditions commonly found in dry mouth patients including antimicrobial properties, lubrication, antiinflammatory, and anti-caries activities [26][27][28][29]. Xylitol is a sugar alcohol that functions as a salivary stimulant [30,31]. Although it is difficult to ascertain the exact mechanism that reduced the xermostomic symptoms, the most likely agents were the betaine, which decreases the loss of water from the mucous component of saliva, and the olive oil, which creates a sensation of a frictionless mucosa.…”

Section: Discussionmentioning

confidence: 99%

The Effect of a Combination Saliva Substitute for the Management of Xerostomia and Hyposalivation

Lapiedra

Gómez

Sánchez

et al. 2015

J. Maxillofac. Oral Surg.

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Objective The objective of this study was to evaluate the difference between the combination agent of xylitol, beatine and olive oil in a chewable capsule versus the control agent of a sorbitol tablet in subjects with hyposalivation and xerostomia. Materials and Methods The subjects had xerostomia over 3 months and a measured hyposalivation. The study was 3 weeks in duration, with 2 treatment phases of 1 week and a 7 day wash out period in between. At the end of each treatment phase, subjects returned for a follow up evaluation. At this visit they were given the subjective sensation questionnaire, as well as their unstimulated whole salivary flow and stimulated whole salivary flow were measured. Results There was a greater increase in the unstimulated and stimulated whole salivary flow rate, although the results were not statistically significant. The subjective evaluation as measured by the questionnaire showed that both agents reduced the mean score as compared to the baseline, although only the findings in the active agent was statistically significant (p = 0.0015). Conclusion The significant conclusions found in this study were that the active agent provided a significant subjective improvement in speech, swallowing, and decreased subjective xerostomia as compared to the control tablet. Clinical Relevance This combination agent has a significant effect on patients with subjective xerostomia but does not have a significant effect on objective hyposalivation.

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“…Observa-se na literatura que pesquisas clínicas mostraram a redução no fluxo salivar com a idade (NAVAZESH; BRIGHTMAN;POGODA, 1996;YEH;JONHSON;DODDS, 1998), no entanto outros trabalhos não registraram esta associação (BOURDIOL; MIOCHE; MONIER, 2003;MORITSUKA et al, 2006). Assim, sugere-se que mais pesquisas, utilizando grupos amostrais maiores e eqüitativos, devam ser realizadas, visando identificar os fatores que possam estar relacionados com a presença de xerostomia e a redução no fluxo salivar.…”

Section: Discussionunclassified

Estudo sobre o Fluxo Salivar e Xerostomia em Mulheres na Pré e Pós-Menopausa

SILVA¹

2007

Pesq Bras Odontoped Clin Integr

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RESUMO DESCRIPTORS DESCRITORESMenopausa; Salivação; Xerostomia.Menopause; Salivation; Xerostomia. Salivary Flow and Xerostomia in Premenopausal and Postmenopausal WomenObjetivo: Analisar quantitativamente e comparativamente o fluxo salivar e a ocorrência de xerostomia em mulheres com e sem menopausa através de estudo caso-controle. Método: A amostra foi composta por 40 mulheres, divididas em um grupo de 20 mulheres na pré-menopausa, com faixa etária entre 35 e 44 anos, e um grupo de 20 mulheres na pós-menopausa, com idade variando de 51 a 80 anos. Todas as pacientes foram submetidas à anamnese, através de um questionário com perguntas relativas à xerostomia, e realizada a sialometria total estimulada. A sialometria foi realizada no turno matutino, e os pacientes foram orientados a não escovar os dentes, comer, beber, fumar e evitar exercícios exagerados pelo menos 1 hora antes da coleta. A taxa do fluxo salivar foi expressa em mililitros por minuto (ml/min). Os valores foram analisados da seguinte forma: fluxo normal, de 1,0 a 3,0 ml/min; baixo fluxo, de 0,7 a 1,0 ml/min; hipossalivação, menos de 0,7 ml/min. Como critério de inclusão foi considerado a não utilização de terapia de reposição hormonal, e como critério de exclusão, o prévio ou atual tratamento radioterápico. Foi aplicado o teste do qui-quadrado para verificar associação entre as variáveis (p<0,05). Resultados: Não houve associação significativa entre a menopausa e a xerostomia (p=0,1967), mas observou-se associação entre a menopausa e fluxo salivar nas mulheres examinadas (p= 0,0127), sendo essa evidente entre o fluxo normal e a hipossalivação (p=0,0058). Conclusão: Parece não haver relação entre a menopausa das mulheres com a xerostomia, no entanto, a hipossalivação estava significativamente associada à menopausa nas mulheres examinadas. Purpose:To analyze quantitatively and comparatively the salivary flow and the occurrence of xerostomia in premenopausal and postmenopausal women by a case-control study. Method:The sample was composed by 40 women allocated in a group of 20 premenopausal women aged 35 to 44 years, and a group of 20 postmenopausal women aged 51 to 80 years. All patients underwent a clinical interview by means of a questionnaire arguing on xerostomia and were submitted to total stimulated sialometry. Sialometry was performed in the morning and the patients were instructed not to brush their teeth, eat, drink or smoke and to avoid exaggerated exercises at least 1 hour before sample collection. Salivary flow rate was expressed in milliliters per minute (mL/min). The values were ranked as follows: normal flow = 1.0 to 3.0 mL/ min; low flow = 0.7 to 1.0 mL/min; hyposalivation = less than 0.7 mL/ min. The non-use of hormone reposition therapy was considered as an inclusion criterion, while previous or current radiotherapy was considered as an exclusion criterion. Chi-square test was applied to verify the association between the variables (p<0.05).Results: There was no statistically significant association (p=0.1967) between menopa...

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Quantitative assessment for stimulated saliva flow rate and buffering capacity in relation to different ages

Cited by 65 publications

References 24 publications

Salivary microbial and nonmicrobial parameters in children with fixed orthodontic appliances

Salivary microbial and nonmicrobial parameters in children with fixed orthodontic appliances

The Effect of a Combination Saliva Substitute for the Management of Xerostomia and Hyposalivation

Estudo sobre o Fluxo Salivar e Xerostomia em Mulheres na Pré e Pós-Menopausa

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