Quantitative anomaloscopy and optical coherence tomography scanning in central serous chorioretinopathy

Abstract

ABSTRACT.Background: Dyschromatopsia is a prominent sign in a variety of central retinal diseases, such as central serous chorioretinopathy (CSC). The changes in colour vision may be due to either optical or neuronal factors in the diseased retina. The relative contribution from the two causes is unknown, but may be elucidated by obtaining knowledge of the anatomical derangement in the diseased retina in CSC. Methods: Twenty-six normal persons had their colour vision tested using the Tomey anomaloscope. The calculation of setting range (SR) and central mean point (CMP) for Rayleigh match and Moreland match was optimized, and normal ranges for these values were defined. Subsequently 24 patients with CSC were examined by anomaloscopy and optical coherence tomography scanning, and the measures of colour vision were related to the anatomical changes observed on the scans. Results: The algorithm for calculating SR and CMP which is integrated into the Tomey anomaloscope could be considerably improved to increase sensitivity and reproducibility of these measures. Fifteen patients had abnormal colour vision. Nine patients had pseudo-protanomaly, seven patients had pseudo-tritanomaly, and three patients had abnormalities in both matches. There was no relation between these colour vision abnormalities and the anatomical derangement as seen by OCT in the diseased central retina. Conclusion:The findings argue against the notion that the density of retinal cell nuclei, the orientation of photoreceptors, or the size of the central serous detachment are related to the colour vision abnormalities in CSC. The question of whether these abnormalities are due to optical or neuronal factors remains open.

Effect of a yellow intraocular lens on scotopic vision, glare disability, and blue color perception

“…However, this was minimized with the development of the Moreland 2 equation incorporated in the HMC anomaloscope. 24,45,46 Ishida et al 47 found that the color sensitivity in the 400 to 440 nm range of eyes with conventional IOLs often declined rapidly with age. In our study, we found significant deterioration in blue vision with age in both IOL groups, with no significant difference between groups in the 3 age ranges.…”

Retinal thickness and perimetric sensitivity in central serous chorioretinopathy

“…4 Our next clinical interest in CSC is the relationship between morphologic abnormalities, including retinal thickness, the height of serous retinal detachment, and perimetric sensitivity loss, in eyes with CSC. While previous researchers failed to demonstrate a relationship between dyschromatopsia and anatomical changes in eyes with CSC using anomaloscopy and optical coherence tomography (OCT), 5 a recent study using OCT and a new fundus perimeter, the MP1, has shown good correlation between maximal retinal thickness and mean threshold values in the corresponding visual fi elds in eyes with CSC. 6,7 In the present study, we initially investigated the relationship between retinal thickness and perimetric sensitivity loss using the Humphrey perimetry central 10-2 program in nine sector areas in the macula.…”

The predictive value of subjective symptoms and clinical signs for the presence of treatment‐requiring exudative age‐related macular degeneration

“…In spite of this, the study showed a significant difference between patients with treatment-requiring exudative AMD and patients not requiring treatment with respect to all the studied parameters, except for micropsia. Micropsia is the subjective sensation of a minification of the central few degrees of the visual field, typically seen in central serous chorioretinopathy (Bek & Kandi 2000;Dinc et al 2010). The lack of correlation between treatment-requiring exudative AMD and the occurrence of micropsia is probably because of the fact that the development of this symptom requires a fovea-centred elevation, often secondary to drusen or oedema, but preserved central retinal function.…”