Retinal thickness and perimetric sensitivity in central serous chorioretinopathy

Sekine, Arata; Imasawa, Mitsuhiro; Iijima, Hiroyuki

doi:10.1007/s10384-010-0869-y

Cited by 13 publications

(9 citation statements)

References 14 publications

(17 reference statements)

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“…The decreased VA measured under mesopic conditions in our study is probably due to impairments of both cone and rod function. This is consistent with the results of the Humphrey perimetric retinal sensitivity decrease in the detached area in eyes with central serous chorioretinopathy …”

Section: Discussionsupporting

confidence: 92%

“…Recent advances in OCT have provided some correlations of the foveal microstructure with visual function in several retinal diseases . Sekine, Imasawa and Iijima reported that the thickness of the serous retinal detachment and not neurosensory retinal thickness, was significantly correlated with visual sensitivity measured by automated static perimetry in eyes with central serous chorioretinopathy. It was also reported that the initial VA was significantly worse in eyes with a higher serous retinal detachment in Vogt‐Koyanagi‐Harada disease but it was not significantly correlated with foveal thickness .…”

Section: Discussionmentioning

confidence: 99%

“…It is well known that VA is affected by the degree of ambient luminance and Shaler reported that the VA of normal eyes decreased under low luminance conditions. Because patients with good VA can have depressed visual function, for example, decreased contrast sensitivity, poorer colour discrimination, reduced focal macular electroretinogram (ERG), reduced focal retinal sensitivity and visual field defects, it might be expected that patients with central serous chorioretinopathy would also have decreased VA under low luminance. There have been no studies focusing on low luminance VA in patients with central serous chorioretinopathy.…”

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confidence: 99%

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Low luminance visual acuity in patients with central serous chorioretinopathy

Fujita

Shinoda

Matsumoto

et al. 2013

Clinical and Experimental Optometry

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Background The aim was to determine the low luminance visual acuity in eyes with central serous chorioretinopathy. Methods Seven eyes of seven patients with central serous chorioretinopathy and six eyes of six age‐matched normal volunteers were examined. Low luminance visual acuity charts were created by an Apple Power Mac G5 computer and displayed on a cathode ray tube monitor (SONY GDM‐F500). The background luminance was set at six different levels from 78.20 cd/m2 to 0.37 cd/m2. The visual acuities of the eyes with central serous chorioretinopathy at each of the six luminance levels were compared to those from their fellow eyes and to normal eyes. Results The mean visual acuities varied from 0.13, 0.23, 0.29, 0.42, 0.62 to 0.70 logMAR units as luminance varied from high to low. At the lowest luminance (0.37 cd/m2), five of the seven eyes could not read any character. The mean visual acuities of the fellow eyes at the same luminance levels were 0.03, 0.06, 0.11, 0.20, 0.27 and 0.45 logMAR units and those of the normal volunteers were 0, 0.03, 0.08, 0.14, 0.23 and 0.38 logMAR units, respectively. The visual acuities of the eyes with central serous chorioretinopathy were significantly poorer than those of the normal eyes at all luminance levels except 0.37 cd/m2 (p < 0.05 for all). Conclusions Although the eyes from all three groups had 0 logMAR units visual acuity under standard testing condition, the visual acuity of the eyes with central serous chorioretinopathy were significantly worse at low luminance levels. The low luminance visual acuity may provide information on the visual disturbances reported by central serous chorioretinopathy patients with 0 logMAR units visual acuity.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Low luminance visual acuity in patients with central serous chorioretinopathy

Fujita

Shinoda

Matsumoto

et al. 2013

Clinical and Experimental Optometry

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“…For eyes with RVOME including both BRVO and CRVO, for which there was no statistical difference in either logMAR (0.395 ± 0.337 for BRVO and 0.486 ± 0.449 for CRVO, P = 0.138) or foveal sensitivity (26.8 ± 6.7 for BRVO and 25.6 ± 7.4, for CRVO, P = 0.231), elevated intravenous pressure because of venous occlusion can cause extravasation of plasma components from the retinal circulation into the extracellular space in the neural retina, which may primarily damage conduction in the neural retina leading to visual dysfunction [13,14]. On the other hand, leakage from the choroidal vessels into the subretinal space as a result of the reduced barrier function of the retinal pigment epithelium (RPE) is the chief mechanism for eyes with CSC, in which swelling of the neural retina is minimal [15]. Separation of the photoreceptors from the RPE by subretinal fluid containing plasma components may cause visual dysfunction by inhibiting renewal of the outer segment of the photoreceptors.…”

Section: Discussionmentioning

confidence: 99%

Foveal sensitivity and visual acuity in macular thickening disorders

et al. 2012

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“…Sekine et al25 investigated the relationship between retinal sensitivity measured by Humphrey visual field analyzer and morphological changes in eyes with CSC. They found a significant correlation between retinal sensitivity and height of the serous retinal detachment.…”

Section: Discussionmentioning

confidence: 99%

Microperimetric evaluation of chronic central serous chorioretinopathy after half-dose photodynamic therapy

Fujita¹,

Shinoda²,

Matsumoto³

et al. 2012

OPTH

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BackgroundThe purpose of this study was to determine baseline clinical factors to correlate the outcome of half-dose verteporfin photodynamic therapy (PDT) in eyes with chronic central serous chorioretinopathy (CSC).MethodsIn this prospective, non-comparative, interventional case series, 14 eyes of 14 patients with chronic CSC who received half-dose verteporfin PDT were examined. The best-corrected visual acuity (BCVA), macular sensitivity in the central 4, 8, and 12 degrees, and fixation stability were evaluated at baseline and at months 1, 3, 6, and 12 after half-dose verteporfin PDT. Macular sensitivity and fixation stability were determined by MP-1 microperimetry.ResultsMean retinal sensitivity in the central 4 and 8 degrees was significantly better at 1, 3, 6, and 12 months after half-dose verteporfin PDT than at baseline. BCVA was significantly better after half-dose verteporfin PDT but only after 3 months. Fixation was relatively unstable in three eyes at baseline, but became stable at 12 months. BCVA at 12 months was significantly correlated with pre-PDT fixation stability (r = 0.7120, P = 0.0038).ConclusionHalf-dose verteporfin PDT results in a significant increase in mean central retinal sensitivity for at least 12 months. Our findings indicate that microperimetry is a useful method for evaluating the functional benefits of half-dose verteporfin PDT in eyes with chronic CSC.

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Retinal thickness and perimetric sensitivity in central serous chorioretinopathy

Abstract: Visual sensitivity measured with automated static perimetry is further attenuated by increasing distance between the photoreceptor and retinal pigment epithelium (RPE) in areas of serous retinal detachment in eyes with CSC.

Cited by 13 publications

References 14 publications

Low luminance visual acuity in patients with central serous chorioretinopathy

Low luminance visual acuity in patients with central serous chorioretinopathy

Foveal sensitivity and visual acuity in macular thickening disorders

Microperimetric evaluation of chronic central serous chorioretinopathy after half-dose photodynamic therapy

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