Quantitation of house dust mites and house dust mite allergens in the microenvironment of dogs

Randall, Amy; Hillier, Andrew; Cole, Lynette K.; Kwochka, Kenneth W.; Needham, Glen R.; Wassom, Donald L.

doi:10.2460/ajvr.2003.64.1580

Cited by 25 publications

(52 citation statements)

References 46 publications

(93 reference statements)

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“…Several studies have investigated the biology, ecology and allergenic potential of HDMAs in humans and dogs. [8][9][10][11][12][13][14][15] These have informed strategies for allergen avoidance, environmental control and specific immunotherapy used in the management of canine and human AD. The most common HDM species associated with human and canine AD are Dermatophagoides farinae and D. pteronyssinus.…”

Section: Introductionmentioning

confidence: 99%

Group 1 and 2Dermatophagoideshouse dust mite allergens in the microenvironment of cats

Loft

Rosser

2010

Veterinary Dermatology

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House dust mite allergens (HDMAs) are some of the most common allergens associated with allergic diseases in humans and dogs. The purpose of this study was to determine whether HDMAs could be detected in cat-associated household microenvironments. From 50 cat-only households with 95 cats, dust samples were collected by vacuuming for 2 min m(-2) from three areas where cats slept or rested regularly from September to October 2006. Relative humidity and temperature were measured in each household using a data logger. Each owner completed a questionnaire on potential factors that might influence the prevalence of house dust mites (HDMs). Dust samples were analysed utilizing an ELISA for Der p 1, Der f 1 and HDM group 2 allergens. In 38 of 50 households there was greater than 2 microg g(-1) of dust for at least one HDMA. Using stepwise logistic regression, factors associated with increased HDMA levels included: free-standing houses, number of humans in household, longhaired cats and age of the cat. Factors associated with decreased HDMA concentrations included: forced air heating and central air conditioning, less than 50% carpeting of the home, use of flea control, cats suffering from dermatological disease and the average temperature of the household. Many sleeping/resting areas utilized by cats contain sufficiently high levels of HDMAs to be potential sources of sensitization. This finding should lead to further determination of the role of HDMs in cats suffering from putative allergic conditions such as atopic dermatitis or asthma.

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Section: Introductionmentioning

confidence: 99%

Group 1 and 2Dermatophagoideshouse dust mite allergens in the microenvironment of cats

Loft

Rosser

2010

Veterinary Dermatology

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“…As previous records of the house dust mite species Euroglyphus maynei (Acariformes: Pyroglyphidae) in Ireland are not known, this may be the first confirmed record of this species in Irish homes. Dermatophagoides pteronyssinus, the most abundant species found, was present in all homes and at higher frequencies than those reported from similar biotopes in other countries (Randall et al, 2003;Jackson et al, 2005;Farmaki et al, 2010). Climate has previously been shown to affect mite numbers, with generally higher densities found in humid, temperate climates in contrast with dry, arid ones (Crisafulli et al, 2007).…”

Section: Discussionmentioning

confidence: 55%

The influence of household pets on the composition and quantity of allergenic mite fauna within Irish homes: a preliminary investigation

Clarke

Dix

Liddy

et al. 2015

Medical Vet Entomology

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Allergenic mites are responsible for inducing hypersensitive reactions in genetically predisposed people worldwide. Mites in dust from 30 Irish homes with pets (dogs, n = 23; cats, n = 7) were compared with those in 30 homes without pets. House dust mites constituted 78% of all mites recorded, with Dermatophagoides pteronyssinus (Acariformes: Pyroglyphidae) representing 57-72% of mites in furniture and mattresses in both home types compared with only 22% of mites in pet beds. Although storage mites accounted for just 13% of all mites recorded, they represented 46% of mites recorded in pet beds. Median levels of the dust mite allergen Der p 1 (µg/g) in dust samples from mattresses in homes without pets were significantly greater than in mattresses from homes with pets, reflecting the greater densities of D. pteronyssinus found in the former home category. Mite species richness was greater in homes with pets (17 species) than in homes without pets (13 species). This suggests that although the presence of pets can result in a wider variety of epidemiologically important mite species within households, increased competition among mite species may result in a more balanced mite fauna in the home, inhibiting the dominance of any one species and hence lowering allergen-associated risks.

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“…The presence of the aforementioned mite species and their allergens, including Der f 1, Der p 1, and Group 2 allergens, has been previously confirmed in the bedding, skin, hair coat, and dry food of clinically healthy dogs (Eaton et al 1985, Randall et al 2003, Brazis et al 2008). Meanwhile, only few studies have attempted to determine the concentration of mite allergens in the fur and household microenvironment of dogs with AD.…”

Section: Introductionmentioning

confidence: 75%

Evaluation of the concentration of allergens from mites in fur and households dust of dogs with atopic dermatitis

et al. 2017

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2 was vacuumed for 2 min. The samples were collected in separate filters, transferred into plastic containers, sealed and kept frozen until ELISA analysis. In the fur of atopic dogs the average concentration of Der p 1 was 0.25µg/g compared to 0.03µg/g in healthy dogs. In households with atopic dogs the highest concentrations of Der p 1 were found in carpets (2.18µg/g), followed by couches (1.53µg/g), beds (1.14µg/g), dogs' bed linen (0.64µg/g) and floors (0.14µg/g). The concentrations of Der p 1 on carpets, couches and beds were significantly higher than in atopic dogs' fur (p<0.05). There was no statistical difference when comparing the concentrations of Der f 1 and Blo t 5 in different environments of atopic dogs (p>0.05). The concentrations of Der p 1, Der f 1 and Blo t 5 were equivalent in atopic and non-atopic dog's households. Among the allergens studied, Der p 1 was the most commonly found, predominantly in carpets and couches.

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Quantitation of house dust mites and house dust mite allergens in the microenvironment of dogs

Abstract: Results indicated the presence of HDMs and HDM allergens in the specific microenvironment of dogs in homes. Factors associated with high levels of exposure were identified, which may be associated with increased risk for sensitization and development of atopic diseases.

Cited by 25 publications

References 46 publications

Group 1 and 2Dermatophagoideshouse dust mite allergens in the microenvironment of cats

Group 1 and 2Dermatophagoideshouse dust mite allergens in the microenvironment of cats

The influence of household pets on the composition and quantity of allergenic mite fauna within Irish homes: a preliminary investigation

Evaluation of the concentration of allergens from mites in fur and households dust of dogs with atopic dermatitis

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