Quantification of tyramine in different types of food using novel green synthesis of ficus carica quantum dots as fluorescent probe

Abstract

Tyramine (TYM) is catecholamine releasing compound and TYM rich food causes hypertensive crisis due to a combination with monoamine oxidase inhibitor (MAOIs). Therefore, analysis of TYM in TYM rich food as (old cheese, cured meat, sausage, pickled olive and canned fish) and the environment is essential for hypertensive patients and to improvement of food industries. In this work, TYM was analyzed in different types of food using novel green synthesis carbon dots from Ficus carica (fig fruits). The gradual addition of TYM to polyamine carbon quantum dots (PA@CQDs) led to enhancement of the quantum dots fluorescence due to formation of hydrogen bonding between quantum dots and TYM. The calibration graph was plotted in the range 5–400 ng mL−1. The method was applied for the determination of TYM in different types of food as old cheese, cured meat, sausage, pickled olive and canned fish. The lower limit of quantitation (LOQ) was found to be 1.68 ng mL−1. The method was successfully applied for the quantification of TYM in varying types of food with high sensitivity and high economic effect due to the reusability of the quantum dots. The optical and morphological characters of quantum dots were studied carefully.

Rapid One-Pot Microwave Assisted Green Synthesis Nitrogen Doped Carbon Quantum Dots as Fluorescent Precursor for Estimation of Modafinil as Post-Covid Neurological Drug in Human Plasma with Greenness Assessments

“…S1 ( Supplementary Materials ). Besides, the powder X-ray diffraction (PXRD) image was utilized to study the formation of N@CQDs, the peak presented at 24.60 o is a diagnostic peak of carbon dots [ 13 , 15 ] as seen in Fig. S2 .…”

“…Moreover, the effect of temperature in the range of (25 – 60 o C) on relative fluorescence intensity (RFI) of N@CQDs was studied. Increasing temperature beyond 25 o C declined the fluorescence intensity [ 13 , 15 ].…”

Ultra-sensitive and selective fluorescence approach for estimation of elagolix in real human plasma and content uniformity using boron-doped carbon quantum dots

“…The quantum yield of B@CQDs was determined using the single point method [ 12 , 17 ]: where, Q st is quantum yield for standard solution (quinine sulphate), (I) is the integrated fluorescence intensity, is the refractive index of the water and A is absorption. B@CQDs have quantum yield 38.44%.Spectrophotometric and spectrofluorimetric equipment were used to analyses the quantum dots' spectrum properties.…”

“…The presented study provides varying advantages other than reported methods as the method is environmentally friendly, time saving, very simple and sensitive with a quantitative range from 4 to 100 ng mL −1 . Quantum dots is smart materials that have many applications as in industries, science, technology, and pharmaceutical analysis [ 12 – 14 ]. As a result, carbon quantum dots were used to analyze ELX in human plasma (pharmacokinetic assay), content uniformity, and then heteroatoms were introduced into carbon dots synthesis to fine-tune the conduction band position of doped CQDs, which led to the adjustment of the functions used to treat impurities and fluorescence of doped carbon dots.…”

“…The presented study provides varying advantages other than reported methods as the method is environmentally friendly, time saving, very simple and sensitive with a quantitative range from 4 to 100 ng mL −1 . Quantum dots is smart materials that have many applications as in industries, science, technology, and pharmaceutical analysis [12][13][14]. As a…”