Quantification of phytochemicals and in vitro antioxidant potential of various solvent extracts of certain species of Acanthaceae

Krishnaswamy, Thenmozhi; Paulsamy, S.; Manian, S.; Krishnamoorthy, Karthika

doi:10.4103/0973-8258.126826

Cited by 3 publications

(1 citation statement)

References 22 publications

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“…52 Therefore, it is reported that the phytochemicals such as flavonoids and phenolics present in this plant might play an important role in scavenging of nitric oxide radicals generated. 53 The present study revealed that the extract showed greater scavenging activity with reference to standard ascorbic acid with IC 50 values of extract and standard were 6.352 μg/ml and 1.477 μg/ml respectively (Figure 8). …”

Section: Resultsmentioning

confidence: 84%

Chemical Profile and Antioxidant Properties of Mundulea sericea

Khyade¹,

Waman²

2017

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Objectives: To evaluate the phytochemical composition and the antioxidant activity of aqueous-methanolic (20:80) leaves extract of Mundulea sericea Willd. Methods: The extract of leaves was tested for antioxidant activity using various in vitro models viz., 2,2-diphenyl-1-picrylhydrazyl (DPPH), nitric oxide, ABTS, ferric reducing antioxidant power (FRAP), total antioxidant activity and reducing power. The phytochemical composition (GC-MS and HPLC) along with total phenolic and flavonoid content of the extract at different concentrations were also determined. Results: Total phenolic and flavonoid contents were found to be equivalents to 107.86 ± 0.53 µg of gallic acid and 44.53 ± 0.156 µg of rutin /mg of dried hydro-methanolic methanolic extract, respectively. Among various antioxidant assays performed, maximum inhibition was observed for ABTS (IC 50 13.26 ± 0.396 μg) followed by DPPH (IC 50 79.83 ± 0.306 μg) and NO (IC 50 6.35 ± 0.23 μg/mL) assay. The GC-MS analysis revealed over 38 compounds; the prevailing compounds were Sec-Butyl ethyl sulfoxide and Di-methyl sulfoxonium formyl methylide. The RP-HPLC analysis further confirmed the presence of rutin, cinnamic acid and salicylic acid. Conclusion:The results of the present study demonstrated that Mundulea sericea leaves possess high phenolic with flavonoid contents and also revealed potential antioxidant activity so these leaves could be used as a viable source of natural antioxidants for industrial and pharmaceutical preparations.

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Section: Resultsmentioning

confidence: 84%

Chemical Profile and Antioxidant Properties of Mundulea sericea

Khyade¹,

Waman²

2017

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Peristrophe bicalyculata extract and quercetin ameliorate high fat diet- streptozotocin-induced type ii diabetes in Wistar rats

Iwara

Mboso

Eteng

et al. 2022

Pharmacological Research - Modern Chinese Medicine

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Synthesis, Structure and Antioxidant Activity of Mixed Ruthenium(III) Benzoyl Pyridine Complex

Eswaran¹,

Anusuya²,

Anusuya³

et al. 2020

Asian J. Chem.

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A new ruthenium arsine complex was prepared by reacting equimolar ratio of [RuBr3(AsPh3)3] and 2-benzoyl pyridine. It was characterized by microanalysis, FT-IR and single crystal X-ray diffraction studies. X-ray diffraction data showed the distorted octahedral geometry of the complex. The pyridine nitrogen and carbonyl oxygen of the ligand coordinated with the metal center. Antioxidant activity of the complex was analyzed using different assays, which manifested significant activity. It has been found that a newly synthesized complex possessed better antioxidant activity than the ligand and precursor complex.

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Quantification of phytochemicals and in vitro antioxidant potential of various solvent extracts of certain species of Acanthaceae

Cited by 3 publications

References 22 publications

Chemical Profile and Antioxidant Properties of Mundulea sericea

Chemical Profile and Antioxidant Properties of Mundulea sericea

Peristrophe bicalyculata extract and quercetin ameliorate high fat diet- streptozotocin-induced type ii diabetes in Wistar rats

Synthesis, Structure and Antioxidant Activity of Mixed Ruthenium(III) Benzoyl Pyridine Complex

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