Quality of Life in Patients With Chronic Pancreatitis

Natalskiy, A A; Tarasenko, S. V.; Zaytsev, O V; Bogomolov, A Yu; Peskov, O D; Kadykova, O A

doi:10.31146/1682-8658-ecg-157-9-115-120

Cited by 2 publications

(2 citation statements)

References 2 publications

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“…Одним из основных направлений Государственной программы Российской Федерации «Развитие здравоохранения» в последние годы является создание условий по обеспечению населения медицинской помощью, в рамках которой применяются инновационные, в том числе разработанные и ранее не применявшиеся методы профилактики, диагностики, лечения и реабилитации. Это особенно актуально для больных хроническим панкреатитом (ХП), что обусловлено неуклонным ростом заболеваемости, склонностью к хроническому течению, ранней инвалидизации, значительному ухудшению качества жизни (КЖ) данной категории больных [1][2][3][4]. Данную ситуацию усугубляет пандемия новой коронавирусной инфекции, существенно утяжеляющая течение хронических заболеваний, и в большей степени это касается болезней желудка, печени и поджелудочной железы (ПЖ) [5,6].…”

Section: Introductionunclassified

“…Современные высокоточные методы диагностики дают возможность диагностировать ХП на ранних стадиях, что вносит изменения в клинические протоколы с использованием более агрессивных методов хирургического и эндоскопического лечения [1,3]. Ранняя диагностика ХП и его своевременное лечение дают основание для возможно более раннего использования лечебных физических факторов (ЛФФ) в программах восстановительного лечения больных с целью повышения общей эффективности терапевтических мероприятий.…”

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Therapeutic physical factors in treatment programs for patients with chronic pancreatitis

Кайсинова¹,

Efimenko

Uzdenov

et al. 2023

jour

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The purpose of the study is to study the eff ectiveness and safety of using therapeutic physical factors in rehabilitation treatment of patients with chronic pancreatitis in hospitals.Material and methods. There has been carried out an open randomized controlled trial which included 95 patients with chronic biliary pancreatitis of stage II-III, moderate severity, in the stage of exacerbation, not requiring surgical treatment. Two groups were formed by simple randomization. The patients of the control group (n = 46) had stationary treatment in accordance with Russian clinical guidelines; in the main group (n = 49) the patients were prescribed low-mineralized mineral water in the form of ingestion and electrophoretics according to the mitigated methods in addition to the treatment complex.Results. The inclusion of low-mineralized sulphate-hydrocarbonate calcium-sodium mineral waters in the treatment complex of patients with chronic pancreatitis in hospitals, their ability to enhance pharmacological potential of the used drugs at the stationary stage provided a signifi cant reduction of clinical and ultrasound indicators with 76.56% of the patients at reduction of pain syndrome in 3.56 (p < 0.01) times, diarrhea -1.94 (p < 0.01), decrease in enzymatic activity -3.16 (p < 0.01), acutephase blood values -in 3.14 (p < 0.01), improvement of metabolic status -in 2.29 (p < 0.01) times. This helped to reduce the length of stay in a 24-hour hospital by 2.7 days, reliably signifi cant in comparison with the data in the control group based on the treatment in accordance with Russian clinical recommendations. In addition, a comparable number of adverse drug reactions were detected in both groups (8.13% verses 10.63%), which indicates equal safety of the used medical technologies. Conclusion.Inclusion of therapeutic physical factors in the complex of treatment of patients with chronic pancreatitis in hospitals provides reliably signifi cant increase of therapeutic measures eff ectiveness.

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Section: Introductionunclassified

Therapeutic physical factors in treatment programs for patients with chronic pancreatitis

Кайсинова¹,

Efimenko

Uzdenov

et al. 2023

jour

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Pancreatic lesion in children with nephrotic syndrome

Бекмурзаева

Османов

2021

Medicinskij sovet

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Nephrotic syndrome occupies one of the leading places among kidney diseases in children. Scientific studies indicate that edema syndrome, arterial hypertension, disorders on the microcirculatory level occurring in case of nephrotic syndrome contribute to the slowing and reduction of blood flow in the pancreas, which leads to the development of hypoxia and metabolic disorders. Under conditions of metabolic and microcirculatory disorders, as well as against the background of the therapy used in children with nephrotic syndrome the risk of secondary pancreas lesion increases significantly. Pathogenetic treatment of nephrotic syndrome involves the administration of glucocorticosteroid and cytostatic therapy. The study of autopsy materials of the pancreas in children who died of glomerulonephritis revealed histomorphological changes in 35.7% of children in the form of acute interstitial pancreatitis and pancreonecrosis. At the same time there are still few works in the scientific literature, devoted to the study of functional state of the pancreas in children with kidney diseases. The data on pancreatitis prevalence in children are extremely inconsistent. Significant variation in the frequency of pancreatic lesion in children (from 5 to 25%) is most often associated with diagnostic difficulties. Ultrasound examination after a meal (postprandial test) allows to diagnose pancreatic pathology (indirect signs of chronic pancreatitis, reactive pancreatic changes) with higher accuracy (by 23%) than traditional examination. Late diagnosis of pancreatic lesion and lack of correction can significantly affect patients’ health and quality of life. There is a need to study functional state of pancreas in children with nephrotic syndrome to improve understanding of pathogenesis of possible involvement in pathological process and optimization of preventive and therapeutic tactics.

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Quality of Life in Patients With Chronic Pancreatitis

Cited by 2 publications

References 2 publications

Therapeutic physical factors in treatment programs for patients with chronic pancreatitis

Therapeutic physical factors in treatment programs for patients with chronic pancreatitis

Pancreatic lesion in children with nephrotic syndrome

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