Quality of life and pain multidimensional aspects in individuals with HTLV-1

Abstract

HTLV-1 creates a chronic health condition that involves moderate to severe pain with a negative impact on quality of life (QoL). There is no consensus on which attitudes to pain are more related to the worsening of QoL in HTLV-1 infected patients. The aim of this study was to investigate the correlation between QoL and multidimensional aspects of pain in patients with HTLV-1. A cross-sectional study was conducted in Salvador, Bahia, Brazil. The study included individuals diagnosed with HTLV-1. The Short Form 36 Questionnaire was used to analyze QoL, and the Brief Pain Inventory was used to assess multidimensional aspects of pain. The mean pain intensity was 4.88±3.06 on the visual pain scale, and the average impact on QoL corresponded to a loss of approximately 40%. Moderate to high correlations between pain intensity and all domains of QoL were observed and compared reaction attitudes for general activity, mood, ability to walk, ability to work, relationships, sleep, and ability to enjoy life (r>0.40; p<0.05). Moderate correlations were found between all domains of QoL, pain intensity, and reactive attitudes to pain. The greatest pain intensity impacts involved difficulty to walk and to work, and interpersonal relationships in the emotional aspect of QoL.

Stability of the HTLV-1 glycoprotein 46 (gp46) gene in an endemic region of the Brazilian Amazon and the presence of a significant mutation (N93D) in symptomatic patients

“…Approximately two-thirds of the patients analyzed in the present study were symptomatic, a rate similar to that recorded in the endemic region of Salvador, Brazil, where 84.3% of patients reported some type of symptom, in particular pain, during their treatment [ 29 ]. This relatively high rate may be related to the nature of the subset of patients treated in the outpatients clinic of the TMN/UFPA, which includes family cases, screened blood donors, and other individuals under investigation.…”

Limitations in daily activities, risk awareness, social participation, and pain in patients with HTLV-1 using the SALSA and Participation scales

“…Sociodemographic factors, as well as the means of transportation used, and environmental issues can contribute to the onset of pain in people without symptoms. 30 , 31 Those factors may also explain the presence of pain in asymptomatic patients in this study, in particular regarding occupations – domestic services – that require physical exertion and fitness.…”

Research scenario in physiotherapy for people with human t-cell lymphotropic virus (HTLV): scientometric study / Cenário das pesquisas em Fisioterapia para pessoas com Human T-Cell Lymphotropic Virus (HTLV): estudo cientométrico

“…Based on the observational studies, it is confirmed that the main problems that affect these patients involve disorders of gait 21,22,8,23 , balance 24,25,26 , pelvic floor 27,28 spasticity 29,30 and pain 10,31,32,33 . These dysfunctions affect daily life activities 5,34 and quality of life 35 .…”