Qualitative and quantitative alterations of bovine serum lipoproteins with ageing

Quincey, D.; Goff, D. Le; Fresnel, J.; Nouvelot, A.

doi:10.1016/0305-0491(87)90266-5

Cited by 4 publications

(4 citation statements)

References 10 publications

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“…The major lipoprotein alterations induced by the anabolic treatment occurred in the HDL fractions, particularly in the lighter density HDL, were: a reduction in the density limits, a decrease in total protein content and a rise in lipid concentration accompanied by an increase in particle sizes. These HDL alterations induced by exogenous steroids are comparable to the HDL changes associated with sexual maturation produced by endogenous steroids (Forte, Bell-Quint and Cheng 1981;Quincey et al 1987). In the treated calves, the HDL composition ressembled that of the adult and in both, the density range containing the density peak of HDL came closer to the density range of the LDL; in contrast, the LDL fractions from control to treated calves showed no change in total weight of lipoprotein and no difference in lipid concentrations or particle sizes.…”

Section: Discussionsupporting

confidence: 49%

Distribution, Composition and Image Analysis of Plasma Lipoproteins in Steroid-Treated Calves

Quincey

Fresnel²,

Goff³

1989

Horm Metab Res

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Six 8-day-old female calves were treated with a subcutaneous implant of 200 mg testosterone + 20 mg estradiol-17 beta. Thirty-five days following implantation, plasma lipoproteins were compared to those in control calves of the same age. The LDL exhibited a slight change in protein and lipid concentrations and no change in particle size. The effects of steroid therapy on HDL and particularly on the lighter density HDL were characterized by a reduction of densities associated with a decrease in protein content, and by a rise in lipids and an increase in particle size. The changes in HDL composition but not in LDL alterations were consistent with those associated with sexual maturation described previously. Although testosterone is the predominant component of our combined preparation, the effects of our treatment on young female calves is not consistent with the data reported for human lipoproteinemia. The high levels of urinary estradiol in treated calves suggest that these effects result more likely from the aromatization of the injected testosterone.

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Section: Discussionsupporting

confidence: 49%

Distribution, Composition and Image Analysis of Plasma Lipoproteins in Steroid-Treated Calves

Quincey

Fresnel²,

Goff³

1989

Horm Metab Res

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“…However, there are few data on the develop mental changes in bovine lipoproteins [5][6][7], To our knowledge, only the study of Forte et al [5] has been carried out on fetal bovines. They reported the morphological and physi cochemical characteristics of ultracentrifugally isolated lipoproteins.…”

Section: Introductionmentioning

confidence: 99%

Developmental Changes in Plasma Apolipoproteins B and A-I in Fetal Bovines

Marcos¹,

Mazur²,

Cardot³

et al. 1991

Neonatology

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Plasma lipid, apolipoprotein (apo) B and apo A-I concentrations were measured in fetal calves in the age range of 4–9 months. The results were compared with those obtained from preruminant calves and cows. The studied lipids and apolipoproteins underwent quantitative changes during development. Fetal calves, as compared to preruminant calves and cows, had a particularly low apo A-I concentration and a high apo B/apo A-I ratio. Unlike adult animals which have two forms of apo B, fetal calves had only high molecular weight apo B (apo Bh). During fetal development triglyceride, cholesterol and apo B concentrations decreased, but apo A-I concentrations remained constant.

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“…To investigate bovine lipoproteins and lipid metabolism, ultracentrifugation, electrophoresis, and gel permeation chromatography techniques have been commonly used [6,15,16]. Among these techniques, gel permeation chromatography is useful for both the analysis and preparation of bovine lipoproteins.…”

Section: Discussionmentioning

confidence: 99%

Utilization of Intestinal Triglyceride-rich Lipoproteins in Mammary Gland of Cows

Uchide

Onda

Bonkobara

et al. 1999

The Journal of Veterinary Medical Science

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ABSTRACT. Elution profiles of total lipoproteins, apolipoprotein B (apoB) concentrations in lipoproteins, and plasma triglyceride (TG) levels were examined in early-, late-, and non-lactating cows. Additionally, arteriovenous (A-V) differences were also measured to elucidate the uptake of TG and apoB-containing lipoproteins in mammary gland. Non-lactating cows showed three major peaks corresponding to triglyceride-rich lipoprotein (TRL), low density lipoprotein (LDL), and high density lipoprotein (HDL) fraction, whereas both early-and late-lactating cows revealed two peaks corresponding to TRL and HDL. The peak area of TRL in early-and late-lactating cows were significantly (p<0.05) smaller than that in non-lactating cows. The plasma TG levels and apoB-48 concentrations of TRL in early-and late-lactating cows were also significantly (p<0.01) lower. Furthermore, early lactating cows showed significantly (p<0.05) larger A-V differences in both plasma TG and apoB-48 concentration of TRL than those in late-and non-lactating cows. These results suggested that TG in exogenous (intestinal) TRL was utilized for milk fat synthesis in lactating mammary gland of cows by the receptormediated uptake.-KEY WORDS: apolipoprotein B, cattle, lipoprotein profile, mammary gland, triglyceride-rich lipoprotein.

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Qualitative and quantitative alterations of bovine serum lipoproteins with ageing

Cited by 4 publications

References 10 publications

Distribution, Composition and Image Analysis of Plasma Lipoproteins in Steroid-Treated Calves

Distribution, Composition and Image Analysis of Plasma Lipoproteins in Steroid-Treated Calves

Developmental Changes in Plasma Apolipoproteins B and A-I in Fetal Bovines

Utilization of Intestinal Triglyceride-rich Lipoproteins in Mammary Gland of Cows

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