Q-switched 532 nm Nd:YAG laser therapy for physiological lip hyperpigmentation: novel classification, efficacy, and safety

Altalhab, Saad; Al‐Jamal, Mohammed; Mubki, Thamer; AlNomair, Naief; Algoblan, Shoug; Alalola, Ammar; AlJasser, Mohammed I.; Al-Issa, Ahmed

doi:10.1080/09546634.2020.1805400

Cited by 10 publications

(14 citation statements)

References 17 publications

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“…1 Other complications include mottled hypopigmentation and reactivation of herpes labialis (HL). 2,15 In our study, all patients did not have a history of HL. Given that pico toning is generally considered as a nonablative laser procedure, the prophylactic antiviral treatment was not prescribed to the patients included in this study.…”

Section: Discussionmentioning

confidence: 87%

“…This is in contrast to the other pigmented laser procedures performed on the lip, wherein they had to use topical anesthetic to decrease the pain and discomfort of the patient. 6,15 There were several limitations that may affect the discrepancy of the clinical and objective assessment of the present study. First, the measurement of the melanin index was performed in a designated area of 5 3 5 mm 2 in each patient's lip on every follow-up visit, whereas the physician and patient assessed the improvement of the lip pigmentation as a whole.…”

Section: Discussionmentioning

confidence: 93%

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The Efficacy and Safety of a 755-nm Picosecond Laser in the Treatment of Physiologic Lip Hyperpigmentation in Thai Patients

Manuskiatti

Apinuntham

et al. 2022

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BACKGROUND Physiologic lip hyperpigmentation is a common aesthetic concern, especially in Southeast Asia. There is limited data on the application of the picosecond laser for this condition. OBJECTIVE To evaluate the efficacy and safety of using a 755-nm picosecond laser in the treatment of physiologic lip hyperpigmentation. METHODS Twenty healthy patients with physiologic lip hyperpigmentation received 5 bi-weekly treatments with a 755nm picosecond laser using a 6-mm spot size, fluence of 0.71 J/cm 2 at 5 Hz. Subjective and objective evaluation on the improvement of lip hyperpigmentation were obtained at baseline, 2 weeks after each treatment and at 1, 3, and 6 months after the final treatment. Patient self-assessment, pain score, and adverse reactions were also recorded. RESULTS All patients completed the study and attended all follow-ups. Most (52.6%) patients presented with moderate clinical improvement at 6-month follow-up. The average melanin index decreased significantly after the fourth treatment (p 5 .048) and at 1-month follow-up (p 5 .026). More than half the patients (70%) reported moderate-to-marked improvement at 6-month follow-up. Only 1 patient presented with a transient adverse reaction of lip edema. CONCLUSION The 755-nm picosecond laser is safe and effective for the treatment of physiologic lip hyperpigmentation in Thai patients.

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Section: Discussionmentioning

confidence: 87%

Section: Discussionmentioning

confidence: 93%

The Efficacy and Safety of a 755-nm Picosecond Laser in the Treatment of Physiologic Lip Hyperpigmentation in Thai Patients

Manuskiatti

Apinuntham

et al. 2022

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“…Laser therapy that targets melanin or water (ablative fractional carbon dioxide laser or non-ablative fractional Erbium laser) is generally safe and effective for patients with Fitzpatrick I–III skin types. 16 , 17 However, the Asian population presents a higher risk of side effects, such as post-inflammatory hyperpigmentation (PIH) after aesthetic therapy due to higher melanin density. 18 , 19 Furthermore, the etiology of IDC is complicated by ethical factors.…”

Section: Discussionmentioning

confidence: 99%

A Prospective Trial of the Microneedle Fractional Radiofrequency System Application in the Treatment of Infraorbital Dark Circles

Wu¹,

Liu²,

Zhu³

et al. 2022

CCID

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Background Infraorbital dark circles (IDC) are commonly consulted in aesthetic practice. There is not yet a multifactorial approach to facilitating their treatment. Objective To investigate the safety and efficacy of the microneedle fractional radiofrequency (MRF) system for the treatment of IDC. Methods A prospective, split-face, evaluator-blind clinical trial was conducted to study the change in the overall appearance, color, and wrinkles in 21 female patients with mixed type IDC before and after MFR treatment. Results Both patients and independent evaluators found significant improvement on the global aesthetic scales after the MFR treatment, especially on periorbital wrinkles (p=0.031). Trends in decreased melanin density in the IDC area were found, but no statistical differences were established. No side effects were observed. Conclusion MFR is a safe and effective modality for improving mixed type IDC by correcting the structural factors.

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“…Additionally, only few studies examined the safety and efficacy of laser treatment in skin of color [ 13 , 14 ]. The efficacy and safety data of nonablative fractional laser in Saudi patients is limited [ 15 , 16 ] with no data that focus on new technologies such as 1550 nm/1927 nm dual wavelength laser. The objective of the current study was to examine efficacy and safety of nonablative 1927 nm wavelength laser followed by a depigmenting cream in the treatment of Saudi patients with PIH.…”

Section: Introductionmentioning

confidence: 99%

“…Additionally, only few studies examined the safety and efficacy of laser treatment in skin of color [13,14]. e efficacy and safety data of nonablative fractional laser in Saudi patients is limited [15,16] with no data that focus on new technologies such as 1550 nm/1927 nm dual wavelength laser.…”

Section: Introductionmentioning

confidence: 99%

1927 nm Thulium Laser Successfully Treats PostInflammatory Hyperpigmentation in Skin of Color

Alharbi

2021

Dermatology Research and Practice

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Background. Treatment of postinflammatory hyperpigmentation (PIH) in patients with dark skin is challenging as the treatment itself might provoke paradoxical PIH. Only few studies examined the safety and efficacy of nonablative laser treatment in these patients. The objective was to examine efficacy and safety of nonablative 1927 nm wavelength laser followed by bleaching creams in the treatment of PIH. Methods. It was a prospective interventional pilot study that was conducted during 2019. All patients were of Fitzpatrick skin type IV who had unsatisfactory response to topical bleaching creams used for at least three months. Patients received one to four sessions of laser treatment (6 weeks apart) followed by topical hydroquinone 4% cream twice daily for 6 weeks. Improvement was assessed by two blinded independent dermatologist evaluators. Results. A total of nine patients were enrolled and the outcome could not be assessed in one patient who was lost for follow-up. The affected sites were the abdomen, face, and other body parts. Three of the eight evaluated patients had excellent response (37.5%), four had satisfactory response (50.0%), and one had nonsatisfactory response (12.5%). The downtime was manifested as edema and erythema that disappeared after 5 to 7 days. Improvement was more evident in first session and it declined in subsequent sessions. None of the patients had paradoxical pigmentation after treatment. Conclusions. Low energy low density nonablative fractional 1927 nm wavelength laser treatment followed by topical hydroquinone 4% cream for 6 weeks is a safe and effective modality for improving PIH in patients with darker skin types.

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Q-switched 532 nm Nd:YAG laser therapy for physiological lip hyperpigmentation: novel classification, efficacy, and safety

Cited by 10 publications

References 17 publications

The Efficacy and Safety of a 755-nm Picosecond Laser in the Treatment of Physiologic Lip Hyperpigmentation in Thai Patients

The Efficacy and Safety of a 755-nm Picosecond Laser in the Treatment of Physiologic Lip Hyperpigmentation in Thai Patients

A Prospective Trial of the Microneedle Fractional Radiofrequency System Application in the Treatment of Infraorbital Dark Circles

1927 nm Thulium Laser Successfully Treats PostInflammatory Hyperpigmentation in Skin of Color

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