Pustular Necrotizing Angiitis

Díaz, Luis A.

doi:10.1001/archderm.1973.01620220076022

Cited by 16 publications

(3 citation statements)

References 33 publications

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“…Generalized sterile pustulation can be seen in many diseases, i. e. psoriasis (4), impetigo herpetiformis (5), subcorneal pustular dermatosis Table 1 Table 2. Mycoplasma serology in our case (6), bacterial infection (3, 7), mycoplasma infection (2), drug eruption (8), erythema multiforme (9) and necrotizing angiitis (10 home. Macmillan has reported generalized pustular rash due to medication occurring in four patients (8).…”

Section: Discussionmentioning

confidence: 71%

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Generalized Pustular Rash Associated With Primary Atypical Pneumonia

Matsubara

Kishimoto

Yasuno

et al. 1982

The Journal of Dermatology

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After the acute onset of primary atypical pneumonia, a 4-year-old girl suddenly developed a widespread, sterile, pustular eruption with predilection toward the distal parts of the extremities. There was no involvement of the muco-ocular area. Histological and electron microscopical examinations revealed intraepidermaI pustule formation containing neutrophils and eosinophils, and perivascular infiltration of lymphocytes, histiocytes, neutrophils and eosinophils. These clinical findings are similar to those of Tan's "acute generalized pustular bacterid" and Teisch's "vesiculopustular eruption with mycoplasma infection". Serological examinations, including complement fixation test, cold agglutination test, and passive hemagglutination test, confirmed a Mycoplasma pneumoniae infection. It is concluded that Mycoplasma pneumoniae infection should be considered in patients with bacterid-like rashes who do not have streptococcal infections.

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Section: Discussionmentioning

confidence: 71%

“…Mycoplasma serology in our case (6), bacterial infection (3,7), mycoplasma infection (2), drug eruption (8), erythema multiforme (9) and necrotizing angiitis (10 home. Macmillan has reported generalized pustular rash due to medication occurring in four patients (8).…”

Section: Discussionmentioning

confidence: 71%

Generalized Pustular Rash Associated With Primary Atypical Pneumonia

Matsubara

Kishimoto

Yasuno

et al. 1982

The Journal of Dermatology

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“…Pustular vasculitis is characterized histologically by leukocytoclastic vasculitis and accompanied sterile spongiform pustules, which often appears as an acute generalized form called pustular necrotizing angiitis [4] or acute generalized pustular bacterid [12] or acute generalized pustulosis [1], Drug and/or infection allergy is suggested to be a possible etioiogic factor and furthermore, immune complexes may play pathogenetic roles of this disorder [9], The patient we describe here had a long-standing history of rheuma toid arthritis (RA), an immune complex disease, and recently noticed pustular vasculitis spreading only on the lower legs. We have investigated a relationship between RA and pustular vasculitis, speculating about circulating immune complexes of this rheumatoid patient as an etioiogic factor.…”

Section: Introductionmentioning

confidence: 99%

Localized Pustular Vasculitis in Rheumatoid Arthritis

Ikehata

Imamura

1982

Dermatology

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This report describes a case of sterile pustulosis accompanied by underlying leukocytoclastic vasculitis which occurred in the absence of apparent infection or drug allergy on the lower legs of a 46-year-old housewife with 10 years’ duration of rheumatoid arthritis. Histamine-induced vascular changes studied by immunofluorescence microscopy demonstrated a perivascular C3 deposition suggesting the presence of immune complexes. We speculate that some unknown triggers have induced trapping circulating immune complexes of this rheumatoid patient, probably an immunopathogenetic factor of rheumatoid arthritis, with subsequent vascular inflammation producing a localized form of pustular vasculitis.

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Acute Generalized Exanthematous Pustulosis

Roujeau¹

1991

Arch Dermatol

446

201

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We retrospectively analyzed 63 observations collected in nine French departments of dermatology of an acute pustular dermatosis, recently named in the French literature acute generalized exanthematous pustulosis (AGEP). Even though 11 of these cases occurred in patients with a history of psoriasis, AGEP appeared distinct from pustular psoriasis based on several slight pathologic differences, drug induction in most cases, and a more acute course of fever and pustulosis, with rapid spontaneous healing. We, therefore, suggest that AGEP is a reaction pattern, perhaps favored by a "psoriatic background." The most frequent causes of AGEP seem to be drug reactions, acute infections with enteroviruses, and hypersensitivity to mercury. With 55 (87%) of 63 cases attributed to drugs in this series, AGEP should be added to the list of cutaneous adverse drug reactions. Among drug-induced skin eruptions, AGEP is remarkable by its short time to onset after the administration of the suspected drug (less than 24 hours in half of our cases) and the great predominance (80%) of antibiotics as causative agents. It is suggested that some cases previously reported as "drug-induced pustular psoriasis" were in fact AGEP.

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Pustular Necrotizing Angiitis

Cited by 16 publications

References 33 publications

Generalized Pustular Rash Associated With Primary Atypical Pneumonia

Generalized Pustular Rash Associated With Primary Atypical Pneumonia

Localized Pustular Vasculitis in Rheumatoid Arthritis

Acute Generalized Exanthematous Pustulosis

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