Pulsed amperometric detection of alkanolamines following ion-pair chromatography

Carbohydrate and alditol analysis by high-performance anion-exchange chromatography coupled with electrochemical detection at a cobalt-modified electrode

“…Figure 4 shows the relevant results obtained in FIA at an applied potential of 0.5 V and using 0.1 mol L -1 NaOH plus different amounts of acetonitrile. In contrast with other common electrode materials, where attenuation of the sensitivity of the amperometric response was observed in mobile phases containing acetonitrile at millimolar levels [29,30], the anodic signals at the GC-Co electrode increased markedly with increasing acetonitrile concentration. In particular, a greatly enhanced amperometric response is observed for sucrose in comparison to that observed for fructose.…”

Pulsed amperometric detection at glassy carbon electrodes: A new waveform for sensitive and reproducible determination of electroactive compounds

“…Since the first papers by Johnson and La Course in the 80's [1,2], pulsed amperometric detection (PAD) at metal electrodes has been exploited for the sensitive and reproducible determination of several compounds (e.g., carbohydrates, aminoacids, and organosulfur species) [1e6]. The proper choice of the electrode material, potential waveform and electrolyte solution is a fundamental aspect to enhance the electrode performance and sensitivity [5].…”

Ion-exchange electrospray ionization liquid chromatography mass spectrometry and tandem mass spectrometry of alkanolamines in wetland vegetation exposed to sour-gas contaminated groundwater

“…1 Most of the available methods are not suited to trace analysis but were developed for target compound analyses of alkanolamines in commercial formulations such as corrosion inhibitors, emulsifying agents, pharmaceuticals and acid-gas scrubbing solutions where concentrations range from 0.1 to 40% (w/w). [10][11][12] These methods employ various techniques, including gas chromatography (GC), [11][12][13][14] ion chromatography (IC), 10,[15][16][17] ion-pair chromatography (IPC), 18,19 reversed-phase liquid chromatography (RP-HPLC), 20,21 GC/mass spectrometry (GC/MS) 12 and liquid chromatography/mass spectrometry (LC/MS). 22 The RP-HPLC and IC methods are most applicable to direct analysis since they are compatible with aqueous samples and polar water-soluble analytes.…”

“…These methods use UV, 15,[20][21][22] . 18 Efficient separations have been achieved using organic resin-based IC phases in reversed-phase or mixed reversed-phase IC modes in which the ionization of the alkanolamines are suppressed using high pH conditions, and are resolved by a reversed-phase retention mechanism. 10 A typical example is the mixed-mode IC method, 23 which uses a Dionex OmniPac PAX-500 analytical IC column (ethylvinylbenzene-divinylbenzene crosslinked polymer with alkanol quaternary amine anion exchange sites) and a pulsed amperometric detector (PAD).…”