Pulmonary Artery Angiosarcoma on 18F-FDG PET/CT Masquerading as Pulmonary Embolism

Kessler, Alexander T.; Son, Hong-Ju

doi:10.1097/rlu.0000000000000614

Cited by 11 publications

(8 citation statements)

References 11 publications

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“…When FDG-PET is done, it can be helpful for the differential diagnosis. It shows increased uptake in the tumoral area and metastases sites [ 12 , 16 , 17 ].…”

Section: Discussionmentioning

confidence: 99%

Acute Cardiac Tamponade Secondary to Cardiac Vascular-Type Pleomorphic Leiomyosarcoma: Case Report

et al. 2021

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Soft tissue sarcomas represent <1% of all neoplasms. Leiomyosarcomas comprise only 5–7% of cases, and only 2% of these are vascular. Vascular leiomyosarcomas are extremely rare and represent only 0.001% of all neoplasms, the venous type being up to 5 times more frequent. Arterial leiomyosarcomas most frequently affect the great vessels, being fatal in most cases. In the reported cases of arterial leiomyosarcomas, the most frequently affected site is the pulmonary artery. We present the clinical case of 2 patients (a 42-year-old woman and a 36-year-old man) with a diagnosis of arterial pleomorphic leiomyosarcoma that conditioned cardiac tamponade as the initial manifestation. As it is an exceptionally rare neoplasm and with few cases reported in the literature, it is important to identify and describe this pathology which, due to the impossibility of offering surgical treatment, represents a therapeutic challenge.

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“…When FDG-PET is done, it can be helpful for the differential diagnosis. It shows increased uptake in the tumoral area and metastases sites [ 12 , 16 , 17 ].…”

Section: Discussionmentioning

confidence: 99%

Acute Cardiac Tamponade Secondary to Cardiac Vascular-Type Pleomorphic Leiomyosarcoma: Case Report

et al. 2021

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“…The flowchart of the patient selection is shown in Figure 4; 19 studies with 21 cases fulfilled these criteria. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] Table 1 summaries the key information in these articles. The mean age of the previously reported patients with pulmonary angiosarcoma was 56.2 years, and in our cases, it was 64 years (range 54-74 years).…”

Section: Discussionmentioning

confidence: 99%

Primary pulmonary angiosarcoma: case reports and review of the literature

Virarkar

Tayyab

Thampy

et al. 2019

Asian Cardiovasc Thorac Ann

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Pulmonary artery angiosarcoma is a rare malignant vascular tumor with an aggressive clinical course and a poor prognosis. Hemoptysis and shortness of breath have been reported as common clinical presentations. The exact clinicopathology is unknown. A tissue specimen obtained by percutaneous fine-needle aspiration cytology or open/thoracoscopic biopsy can confirm the diagnosis based on histopathological and immunohistochemical features. The differential diagnosis includes pulmonary thromboembolism, vascular malformations, and lung carcinoma. There is a paucity of literature describing this tumor, with only a few case reports available. There is also a lack of standardized guidelines for management, which further worsens the survival outcome. We report 3 cases of pulmonary artery angiosarcoma and review the recent literature.

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“…Increased uptake on FDG-PET in the area of the tumor can be helpful in differentiating a neoplasm from a pulmonary embolism, which does not show increased uptake. [ 7 ] The diagnosis can be confirmed by pathological and immunohistochemical examination. When actin, smooth muscle actin, and desmin immunohistochemical results are positive, it is presumed that the tumor originates from smooth muscle.…”

Section: Discussionmentioning

confidence: 99%