Primary pulmonary angiosarcoma: case reports and review of the literature

Abstract

Pulmonary artery angiosarcoma is a rare malignant vascular tumor with an aggressive clinical course and a poor prognosis. Hemoptysis and shortness of breath have been reported as common clinical presentations. The exact clinicopathology is unknown. A tissue specimen obtained by percutaneous fine-needle aspiration cytology or open/thoracoscopic biopsy can confirm the diagnosis based on histopathological and immunohistochemical features. The differential diagnosis includes pulmonary thromboembolism, vascular malformations, and lung carcinoma. There is a paucity of literature describing this tumor, with only a few case reports available. There is also a lack of standardized guidelines for management, which further worsens the survival outcome. We report 3 cases of pulmonary artery angiosarcoma and review the recent literature.

Case Report: Primary Pulmonary Angiosarcoma With Brain Metastasis

“…However, some patients may be asymptomatic during the course of the disease. In this case, the patient was younger than most reported patients (Drosos et al, 2019;Virarkar et al, 2019), and showed only minor coughs with occasional hemosputum, while headache due to metastasis was prominent. These factors contributed the misdiagnosis as tuberculosis.…”