Psychopathy and Functional Magnetic Resonance Imaging Blood Oxygenation Level-Dependent Responses to Emotional Faces in Violent Patients with Schizophrenia

Dolan, Mairead; Fullam, Rachael

doi:10.1016/j.biopsych.2009.03.019

Cited by 109 publications

(90 citation statements)

References 55 publications

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“…First, studies showing reduced amygdala reactivity to fearful faces in antisocial populations have been restricted to children 6,7 and violent patients with schizophrenia and psychopathic features. 8 Second, functional magnetic resonance imaging (fMRI) studies with violent adult populations without severe mental illness have not included a diverse array of positive and negative facial emotions, which is essential to testing the specificity of any neural abnormalities found in this population. Moreover, adult studies have historically relied on relatively small samples of offenders with poorly characterized histories of violence.…”

Section: Current Studymentioning

confidence: 99%

“…5 There is also evidence that children with elevated conduct problems and psychopathic features show an attenuated right amygdala response to fearful faces, 6,7 and psychopathic features have been associated with reduced amygdala reactivity to fearful faces and reduced orbitofrontal cortical reactivity to sad faces in violent adults with schizophrenia. 8 However, not all studies have found a link between psychopathy and amygdala reactivity to fearful faces, 9 suggesting that further research in this area is needed.…”

Section: Introductionmentioning

confidence: 99%

“…12 In contrast, a more recent study found that among violent offenders with schizophrenia, higher levels of psychopathic features were associated with lower amygdala, ventrolateral prefrontal cortex and anterior cingulate reactivity to angry faces. 8 There is accumulating evidence suggesting that chronic vio lence may actually be associated with a more general emotion processing impairment than some theoretical models imply. Psychopathic features often found in chronically violent men have been associated with a diminished physiologic arousal to pleasant pictures and sounds, 13,14 as well as reduced fusiform gyral activation to both positive pictures 15 and happy faces.…”

Section: Introductionmentioning

confidence: 99%

“…16 There is also evidence that adults with psychopathic features exhibit a reduced reactivity in the dorsal and ventral anterior cingulate when processing a diverse array of negative words, 17 and violent patients with schizophrenia and elevated psychopathic traits have a reduced amygdala response to facial expressions of disgust. 8 …”

Section: Introductionmentioning

confidence: 99%

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Neural responses to emotional and neutral facial expressions in chronically violent men

Pardini

Phillips

2010

J Psychiatry Neurosci

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Background: Abnormal neural responses to others' emotions, particularly cues of threat and distress, have been implicated in the development of chronic violence. We examined neural responses to several emotional cues within a prospectively identified group of chronically violent men. We also explored the association between neural responses to social emotions and psychopathic features. Methods:We compared neural responses to happy, sad, angry, fearful and neutral faces between chronically violent (n = 22) and nonviolent (n = 20) men using functional magnetic resonance imaging (fMRI). Participants were prospectively identified from a longitudinal study based on information collected from age 7 to 27 years. We assessed psychopathic features using a self-report measure administered in adulthood. Results: The chronically violent men exhibited significantly reduced neural responses in the dorsomedial prefrontal cortex to all faces, regardless of the emotional content, compared with nonviolent men. We also observed a hyperactive amygdala response to neutral faces in chronically violent men, but only within the context of viewing happy faces. Moreover, they exhibited a greater dorsomedial prefrontal cortex response to mildly fearful faces than nonviolent men. These abnormalities were not associated with psychopathic features in chronically violent men. Limitations: It remains unclear whether the observed neural abnormalities preceded or are a consequence of persistent violence, and these results may not generalize to chronically violent women. Conclusion: Chronically violent men exhibit a reduced neural response to facial cues regardless of emotional content. It appears that chronically violent men may view emotionally ambiguous facial cues as potentially threatening and implicitly reinterpret subtle cues of fear in others so they no longer elicit a negative response.

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Section: Current Studymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Neural responses to emotional and neutral facial expressions in chronically violent men

Pardini

Phillips

2010

J Psychiatry Neurosci

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“…Um menor nível de ativação da amígdala tem sido verificado em psicopatas quando comparados a grupo controle diante da exposição de imagens de impacto emocional envolvendo a violação de normas morais (C.L. Harenski, Harenski, Shane, & Kiehl, 2010), bem como para o processamento de emoções negativas (Dollan & Fullam, 2009) e durante processo de condicionamento aversivo (Rilling et al, 2007). Altera-ções volumétricas, sugerindo um desenvolvimento atrofiado da amígdala também têm sido verificadas em psicopatas na literatura recente (Anderson & Kiehl, 2012).…”

Section: Aspectos Etiológicos E Neurocognitivos Da Psicopatiaunclassified

A cognição social dos psicopatas: achados científicos recentes

Vasconcellos¹,

Salvador-Silva²,

Vargas³

et al. 2017

Estud. psicol. (Campinas)

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ResumoO psicopata apresenta traços na personalidade relacionados à ausência de remorso e uma maior dominância social, expressos muitas vezes como manipulação de outros indivíduos. Em estudos atuais sugere-se que psicopatas podem apresentar deficiências no processamento de estímulos emocionais em uma situação de interação social. Este estudo tem por objetivo realizar uma revisão teórica, não sistemática, discutindo pesquisas recentes sobre o tema. A partir da leitura, conclui-se que novas considerações revelam-se pertinentes, pois nem sempre o tipo de disfunção da cognição social dos psicopatas é explícito na literatura. Sugere-se que outros métodos para avaliar a capacidade dos psicopatas em identificar as emoções possam ser investigadas, além de identificar a medida das estratégias interpessoais. Em termos gerais, apresenta-se uma proposta de reflexão para um transtorno cuja compreensão etiológica deve ser biopsicossocial, contribuindo para assinalar novas direções nas pesquisas voltadas para a cognição social dos psicopatas. Palavras-chave:

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