Pseudochromhidrosis: Blue discolouration of the head and neck

Abstract

A 57-year-old man is presented with blue pseudochromhidrosis affecting the face and neck following combination treatment with lansoprazole, a proton pump inhibitor, and ranitidine, a type two histamine receptor antagonist. The diagnosis was made on the basis of clinico-histological features and growth of Malassezia furfur, and Bacillus species, not Bacillus cereus, in the absence of lipofuscin. The pseudochromhidrosis resolved on stopping both medications and did not recur on restarting only the proton pump inhibitor.

Diseases of cutaneous appendages

“…[1440][1441][1442] Slight coloration of apocrine sweat is not uncommon. 1445 In one case of blue sweat the etiology was never determined. 1443,1444 Blue pseudochromhidrosis has followed the use of combination therapy consisting of a proton pump inhibitor and a type 2 histamine antagonist.…”

A Case of Late-Onset Genital Apocrine Chromhidrosis

“…Malassezia furfur, Bacillus spp., Corynebacterium, Piedra, Pseudomonas gibi çok sayıda kromojenik, porfirin üreten bakteri ve fungusların psödoekrin kromhidroza sebep olduğu bildirilmiştir. 18 Bir diğer psödoekrin kromhidroz nedeni ise dermatitis artefaktanın bir türü olan dermatitis simulatadır. Dermatitis simulata, bir hastalığı taklit etmek için cilde bazı maddelerin sürülmesi ile karakterizedir.…”

Blue Pseudochromhidrosis Secondary to Topiramate Treatment

“…a type two histamine receptor antagonist, triggered the proliferation of M /»/•/»/•and Bacillus spp. and led to a blue pseudochromhidrosis (7).…”