Blue Pseudochromhidrosis Secondary to Topiramate Treatment

Castela, E.; Thomas, P; Bronsard, V.; Lacour, Jean‐Philippe; Ortonne, Jean‐Paul; Passeron, Thierry

doi:10.2340/00015555-0696

Cited by 16 publications

(20 citation statements)

References 7 publications

(5 reference statements)

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“…The drug causes nonscarring alopecia that may be localized or generalized and is apparently associated with telogen effluvium and, thus, reversible. Exanthema, pruritus, fixed drug eruption, acneiform eruptions, and hyperhidrosis can also be related [9,10]. Mild adverse effects might not even be reported by the patients; however, pruritus has warranted case reports [11,12].…”

Section: Discussionmentioning

confidence: 99%

Acneiform Rash Caused by an Unlikely Drug: Topiramate

Bello‐Hernández¹,

Espinoza-Hernández

Moreno‐Coutiño³

2017

Skin Appendage Disord

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Topiramate is an antiepileptic drug that can also be used for migraine prophylaxis, weight control, and even for methamphetamine dependence; the dosage margin is wide, and the list of side effects is shorter than with other anticonvulsants. We present the case of a 35-year-old man with a disseminated rash of the trunk and extremities after treatment with 25 mg of topiramate daily as a prophylactic migraine treatment. This case report is useful, as this patient was not polymedicated and had a score of 7 on the Naranjo Adverse Drug Reaction Probability Scale. The patient was diagnosed as atypical DRESS syndrome and resolved satisfactorily with symptomatic treatment and topiramate withdrawal; slowly, the lesions regressed. He required no further drugs for the dermatologic condition.

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Section: Discussionmentioning

confidence: 99%

Acneiform Rash Caused by an Unlikely Drug: Topiramate

Bello‐Hernández¹,

Espinoza-Hernández

Moreno‐Coutiño³

2017

Skin Appendage Disord

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“…9,11,12 The result of treatment was excellent clearance without any recurrence in the various follow-up periods. 9,11,12 The result of treatment was excellent clearance without any recurrence in the various follow-up periods.…”

Section: Treatmentmentioning

confidence: 88%

“…In terms of chromogenic bacteria cases in the English literature, a majority of the cases were treated with topical erythromycin combined with the oral erythromycin for 1-2 weeks. 9,11,12 The result of treatment was excellent clearance without any recurrence in the various follow-up periods. Even in cases with negative skin scraping cultures, patients were also administered this dual treatment.…”

Section: Differential Diagnosismentioning

confidence: 88%

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Pseudochromhidrosis: report and review of literature

et al. 2017

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Chromhidrosis is a rare condition where colored sweat comes from the apocrine or eccrine glands. Pseudochromhidrosis is an uncommon condition where colored sweat is related to specific dye-producing bacteria, drugs, dyes, or chemical agents. This article provides a literature review of the various etiology, investigation, treatment, and prognosis. We propose an investigative algorithm to assist dermatologists, pediatric dermatologists, and general practitioners to diagnose this uncommon condition. The treatment options rely on the primary etiology such as removing dyes and chemical agents first and then treating the chromogenic bacteria. Topical and oral erythromycin seems to be the most effective treatment both in unidentified and identified chromogenic bacteria cases. Results and prognosis were excellent and without recurrence.

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“…Malassezia furfur and Bacillus spp. have been considered as causes of blue pseudochromhidrosis 5 . In this case report, we describe a 17--year--old girl referred to our hospital because of recurring blue skin discoloration, which disappeared after treatment with an antiseptic scrub.…”

Section: Introductionmentioning

confidence: 99%

Transient Blue Skin: Pseudochromhidrosis

Burggraaff

Linthorst

Hoogerwerf

2014

European Journal of Case Reports in Internal Medicine

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Abstract:Objectives: Pseudochromhidrosis is a rare condition where colours due to chromogenic microbial products or extrinsic chemicals are excreted with sweat. Chromhidrosis is the production of coloured sweat from apocrine or eccrine sweat glands. The aim of this case report is to illustrate all the steps involved in the diagnosis of pseudochromhidrosis. Materials and methods: A 17--year--old patient with pseudochromhidrosis is presented.Results: Clinical features of the patient were consistent with pseudochromhidrosis. Conclusions:The distinction between chromhidrosis and pseudochromhidrosis can be made based on a detailed history, skin biopsy and empiric treatment.

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Blue Pseudochromhidrosis Secondary to Topiramate Treatment

Cited by 16 publications

References 7 publications

Acneiform Rash Caused by an Unlikely Drug: Topiramate

Acneiform Rash Caused by an Unlikely Drug: Topiramate

Pseudochromhidrosis: report and review of literature

Transient Blue Skin: Pseudochromhidrosis

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