Protective Effects of Dietary Nasunin on Paraquat-induced Oxidative Stress in Rats

Extract of the Bark of Bathysa cuspidataAttenuates the Development of Chemically-Induced Preneoplastic Colorectal Lesions in Rats

“…The antioxidant activity of some aqueous and ethanolic extracts of Chinese medicinal plants have been positively correlated to the content of polyphenols and flavonoids (Cai et al 2004;Zhang et al 2011). Other similar studies have demonstrated the antioxidant activity of polyphenols from Solanum melongena (Kimura et al 1999) and Croton cajucara (Tieppo et al 2006), which presented a high concentration of phenolic compounds that were able to suppress the oxidative stress in liver tissue. In the present study, the preliminary phytochemical analysis indicated the presence of flavonoids and polyphenolic compounds -important antioxidant compounds It has already been established that the toxicity of DMH manifests as systemic effects such as lethargy, anorexia, and progressive weight loss in the animals.…”

Boysenberry and blackcurrant drinks increased the plasma antioxidant capacity in an elderly population but had little effect on other markers of oxidative stress

“…42 When oxidative stress was induced in rats by treatment with Paraquat, anthocyanins isolated from eggplant and red cabbage were able to provide some protection and reduced the oxidative damage as measured by several indices. 43,44 In human studies, anthocyanincontaining berry fruit incorporated into juice mixtures increased both antioxidant status (plasma TEAC) and reduced oxidative damage (plasma MDA). 45,46 In contrast, a study in which human subjects consumed 750, 1000 or 1500 mL of a blackcurrant/apple juice combination found no change in plasma antioxidant status, a decrease in plasma MDA, and increase in plasma protein oxidation.…”

Protective Effects of Boysenberry Anthocyanins on Oxidative Stress in Diabetic Rats

“…It has been demonstrated that anthocyanins have the following physiological functions: atherogenic index-lowering effects of ruburobrassicin (cyanidin 3-sophoroside-5-monoglucoside) (Igarashi et al, 1990), serum cholesterol-lowering effect of nasunin from peel of eggplant (Kayamori & Igarashi, 1994), triacylglycerol-lowering effect of malvin (Igarashi & Inagaki, 1991), protective effects of dietary cyanidin 3-O-glucoside on liver ischemia-reperfusion injury (Tsuda et al, 1999b), promoting effect of anthocyanogen for regeneration of rhodopsin (Tronche et al, 1967), protective effect of cyanidin on oxidation of low density lipoprotein (Satue-Gracia et al, 1997), and preventive effects of nasunin and acylated anthocyanins from red cabbage on paraquat-induced oxidative stress in rats (Kimura et al, 1999;Igarashi et al, 2000). Anthocyanins are expected to have even more physiological functions which differ from those above.…”