2006
DOI: 10.1002/cbf.1246
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Protective effect of black tea extract on the levels of lipid peroxidation and antioxidant enzymes in liver of mice with pesticide-induced liver injury

Abstract: Sub-acute hepatotoxicity was induced in mice by exposure to pesticides. The effect of pretreatment with aqueous black tea extract on lipid peroxidation and antioxidants in the liver was investigated. Administering a combination dose of chlorpyriphos and cypermethrin (20 mg kg(-1) each) on alternate days over a 15-day period to male mice resulted in induction of sub-acute toxicity as reflected by elevated levels of liver damage marker enzymes alkaline phosphatase(ALP), aspartate transaminase(AST) and alanine tr… Show more

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Cited by 58 publications
(22 citation statements)
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“…Lipid peroxidation along with the changes p50.05 versus BLM group. DOI: 10.3109/13880209.2014.889176 in radical scavengers is evidence of oxidative stress occurrence (Khan, 2006).…”
Section: Discussionmentioning
confidence: 99%
“…Lipid peroxidation along with the changes p50.05 versus BLM group. DOI: 10.3109/13880209.2014.889176 in radical scavengers is evidence of oxidative stress occurrence (Khan, 2006).…”
Section: Discussionmentioning
confidence: 99%
“…In these studies, oxidative stress markers and other biochemical parameters [7,13,22,27,31], and changes in these parameters upon the administration of detoxifying substances have been investigated [8,14,15,24,45]. However, no previous studies related to effectiveness of propolis against acute cypermethrin exposure exist.…”
Section: Discussionmentioning
confidence: 99%
“…The altered architecture of hepatocytes of alloxan-treated rats is the result of increased ROS attack on lipid membranes. Increased production of ROS in diabetes would be capable of initiating tissue damage in liver, along with pancreas [44,45]. Studies suggest that cellular oxidative stress plays a crucial role in the genesis of hyperglycemia related tissue changes [2].…”
Section: Effect Of Melmentioning
confidence: 99%